Results 161 to 170 of about 117,188 (306)

AI-derived therapeutic development of a serotonin receptor-targeting drug for the treatment of opioid use disorder. [PDF]

Proc Natl Acad Sci U S A
Lallai V, Kho S, Martin AC, Fowler JP, Roach ML, Wang K, Laumann KN, Morrison TG, Palaniappan M, Bautista M, Mogul AS, Cheepluesak JE, Shrestha B, Lade DM, Lagomarsino JE, Narayan V, Uffens J, Lernhardt W, Mirzaei S, Jenkins I, Zavala AR, Lakey JRT, Tinder R, Fowler CD.   +23 more
europepmc   +1 more source

Understanding Substance Use and Suicide Risk Among LGBTQ+ College Students Post‐COVID‐19

Journal of Addictions &Offender Counseling, EarlyView.
ABSTRACT This study examines the reported frequency of substance use, levels of suicide risk, and their relationships among LGBTQ+ college students (N = 192) following the COVID‐19 pandemic. Participants most commonly reported alcohol and marijuana use, and least commonly reported unprescribed prescription opioid or heroin use.
Afroze N. Shaikh, Jordan B. Westcott, Brittney N. R. Irion, Jackie Yang, Illiana R. Navarra‐Bueno, Hannah Martinson, Noah Diaz   +6 more
wiley   +1 more source

A kappa opioid receptor agonist, difelikefalin, improves acute kidney injury in experimental sepsis models. [PDF]

PLoS One
Sawanobori Y, Nakano D, Kitamura H, Kitada K, Asaga T, Suzuki N, Yamamoto M, Ogino Y, Shirakami G, Nishiyama A.   +9 more
europepmc   +1 more source

Exploring the Role of Dysregulated Arousal in the Relationship Between Trauma and Addictive Behaviors Among College Students

Journal of Counseling &Development, EarlyView.
ABSTRACT The relationship between trauma and addictive behaviors is well‐established, yet factors mediating this relationship remain understudied. Given the prevalence of addictive behaviors among collegiate populations, we used path analysis to explore the mediating role of arousal dysregulation in the relationship between childhood trauma and a ...
Amanda L. Giordano, Kate M. Dorrough, Deborah L. Smith, Peitao Zhu   +3 more
wiley   +1 more source

A Review of Alpha-2 Adrenergic Agents Implicated in Opioid Use Disorder. [PDF]

ACS Chem Neurosci
Hannum A, Spano I, Ofori E.
europepmc   +1 more source

On‐site pilot‐scale advanced oxidation pretreatment of hospital wastewater: assessment of pharmaceuticals, pathogens, antibiotic resistance genes and acute ecotoxicity

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Hospital premises generate wastewater containing a wide spectrum of contaminants, such as pharmaceutically active compounds (PhACs), antibiotic resistance genes (ARGs) and pathogenic microorganisms, whilst plenty of them are classified under the antibiotic resistant bacteria (ΑRΒ) category.
Andreas Kaliakatsos, Iosifina Gounaki, Spyros Dokianakis, Georgios Gkotsis, Maria‐Christina Nika, Eleni Aleiferi, Athanasios S Stasinakis, Nikos Katsarakis, Nikolaos S Thomaidis, Thrassyvoulos Manios, Michalis S Fountoulakis, Danae Venieri   +11 more
wiley   +1 more source

Opioids regulate the functional state of immune cells and reduce inflammatory cardiac injury: Role of opioid receptors, MRGPRX2, and TLR4. [PDF]

J Biomed Res
Gusakova SV, Sirotina M, Maslov LN, Slidnevskaya AS, Kilin M, Kurbatov BK, Kan A, Derkachev IA, Fu F.   +8 more
europepmc   +1 more source

Things We Do for No Reason™: Withholding opioids among patients with acute pain and opioid use disorder

Journal of Hospital Medicine, EarlyView.
Abstract Hospitalists care for patients with acute pain who have an opioid use disorder and require pain management. Hospitalists may withhold opioids for acute pain due to a variety of reasons. However, adequate pain management in patients with opioid use disorder, including with opioids, is the standard of care. This piece explains how to best manage
Anna‐Maria South, Susan L. Calcaterra, Marlene Martin   +2 more
wiley   +1 more source

Opioid peptides in autism spectrum disorder and gluten-free casein-free diet as a therapeutic approach. [PDF]

Metab Brain Dis
Öztürk E, Aslan Çi̇n NN, Cansu A, Akyol A.   +3 more
europepmc   +1 more source

Patient and hospitalization differences in incarcerated versus nonincarcerated men: Insights from a 10‐year cohort study

Journal of Hospital Medicine, EarlyView.
Abstract Background The incarcerated population in the United States is underserved and aging rapidly; there is a dearth of information regarding their health, including hospital care. Epidemiological information is crucial to guide policymakers’ planning.
Farah Acher Kaiksow, Amir Forati, Kristin Merss, Karen Reece, Marguerite Burns, Eduard Eric Vasilevskis   +5 more
wiley   +1 more source