Evaluation of AT121 versus morphine on cortical neurons electrophysiology and dopamine concentrations in hippocampal cells. [PDF]
Elawy BE +4 more
europepmc +1 more source
Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu +4 more
wiley +1 more source
Intranasal dexmedetomidine for perioperative analgesia in a patient on naltrexone maintenance therapy. [PDF]
Rangari A, Singh S, Mittal S, Garg H.
europepmc +1 more source
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang +12 more
wiley +1 more source
Peripheral Analgesic Effect of a Novel Curcuminoid Derivative: Possible Involvement of Peripheral Opioid Receptor and ATP-Sensitive Potassium Ion Channel. [PDF]
Lee MT +6 more
europepmc +1 more source
The Application of Telemedicine in Surgery
This figure provides an overview of the content presented in this article. Telemedicine is integrated throughout the entire surgical workflow, with distinct applications across the preoperative, intraoperative, and postoperative phases. These applications are enabled by a suite of supporting technologies, while the associated implementation challenges ...
Yufan Yang +8 more
wiley +1 more source
Essential oil from Eugenia stipitata McVaugh leaves exhibits antinociceptive effect via opioid receptor activation. [PDF]
Costa WK +11 more
europepmc +1 more source
Double Asymmetric Spin Echo EPI (dASE‐EPI) Enables fMRI of the Entire Rat Brain at 9.4 T
ABSTRACT Purpose Development and evaluation of a double asymmetric spin echo planar imaging (dASE‐EPI) sequence to balance sensitivity to blood oxygenation level‐dependent (BOLD) contrast with mitigation of susceptibility‐induced intravoxel spin dephasing in ultra high‐field rodent brain imaging.
Kyle A. Johnson +2 more
wiley +1 more source
Exploring the Pain-Relieving Potential: Unveiling Antinociceptive Properties in Animal Venoms and Toxins. [PDF]
Angstmam DG +6 more
europepmc +1 more source
Abstract Background Pancreatic enzyme insufficiency (PEI) contributes to symptom burden and malnutrition in advanced pancreatic cancer (aPC). We aimed to evaluate the impact of pancreatic enzyme replacement therapy (PERT) on symptom burden and weight during chemotherapy.
Pamela N. Klassen +6 more
wiley +1 more source

