Results 51 to 60 of about 5,557 (173)
Stabilization of Molecular LiF and LiFHF inside Metallamacrocyclic Hosts
Complexes of molecular LiF and LiFHF were synthesized using the metallamacrocyclic receptors [(cymene)Ru(C5H3NO2)]3 (1), [Cp*Rh(C5H3NO2)]3 (2), and [Cp*Ir(C5H3NO2)]3 (3).
Kay Severin (1403713) +2 more
core +1 more source
Leukemia inhibitory factor enhances neurogenin's pro-neural effect during mouse cortical development
Die Entwicklung von unterschiedlichen Zelltypen waehrend der embryonalen ZNS-Entwicklung ist abhaengig von zellintrinsischen und positionsabhaengigen, aeusseren Einfluessen. Dabei bilden sich die verschiedenen Zellen in nacheinander ablaufenden bzw. sich
Hasan, Sascha
core
Schematic summary of the results. Zebrafish RGCs upregulate LIF in response to optic nerve injury.
The resultant LIF then activates Jak/STAT3 signaling via LIF receptors in neighboring RGCs [or on the same (secreting) cell]. Activation of STAT3 leads to the upregulation of regeneration-associated molecules (e.g., GAP-43) directly or indirectly, which ...
Kayo Sugitani (442484) +8 more
core +1 more source
The OSM receptor complexes are expressed in intestinal epithelial cells.
(A) mRNA expression of gp130, LIFR and OSMR-β in various intestinal epithelial cell lines, were analyzed by semiquantitative RT-PCR analysis of mRNA derived from cells as indicated. Sterile water served as negative control.
Florian Beigel (174724) +6 more
core +1 more source
Cytokines are small secreted proteins produced by different cell types in nearly all tissues. They are used as intercellular mediators being involved in the regulation of immunity and inflammation. Dysregulated cytokine production plays an important role
Metz, Silke
core +1 more source
The Effects of Inducible OSM on Metastasis in Breast Cancer
Breast adenocarcinoma is a cancer of glandular cells, and like most carcinomas is mediated by signaling pathways. Oncostatin M (OSM), in particular, is a signaling factor that binds to its receptors to elicit various effects in breast cancer cells ...
Walker, Jeff +3 more
core
Cytokine receptors initiate intracellular signalling that regulate a diverse range of biological and medically important functions including metabolism control, neural stem cell activation, inflammatory responses, bone development, as well as blood cell ...
Farhad Dehkhoda +5 more
core +1 more source
LIF Drives Neural Remodeling in Pancreatic Cancer and Offers a New Candidate Biomarker
International audiencePancreatic ductal adenocarcinoma (PDAC) is characterized by extensive stroma and pathogenic modifications to the peripheral nervous system that elevate metastatic capacity.
Vasseur, Sophie +16 more
core +2 more sources
Activation of Bradykinin B2 Receptors in Astrocytes Stimulates the Release of Leukemia Inhibitory Factor for Autocrine and Paracrine Signaling. [PDF]
Communications between different cell types within a tissue are often critical for the proper functioning of an organ. In the central nervous system, interactions among neurons and glial cells are known to modulate neurotransmission, energy metabolism ...
Lu Y, Gu Y, Chan ASL, Yung Y, Wong YH.
europepmc +2 more sources
We have shown recently that leukemia inhibitory factor (LIF) and oncostatin M (OSM), two members of the gp130-dependent cytokine family, stimulate murine proopiomelanocortin (POMC) transcription and adrenocorticotropin hormone (ACTH) secretion.
Yan, Xinmin +7 more
core +1 more source

