Results 71 to 80 of about 479 (208)

Identification and Discrimination of Sulfated and Unsulfated Gut‐Hormone Biomarkers in Human Serum by Nanopore

Small, EarlyView.
This study discriminates between sulfated and unsulfated cholecystokinin‐8 gut‐hormone forms at single‐molecule‐level resolution. Using an aerolysin nanopore embedded in a hybrid lipid‐polymer membrane, the system produces distinct electrical signatures enabling highly sensitive detection, even in 20% human serum.
Luca Iesu, Laurent Bacri, Juan Pelta, Benjamin Cressiot   +3 more
wiley   +1 more source

Effects of oxytocin receptor agonism on acquisition and expression of pair bonding in male prairie voles

Translational Psychiatry
There is much interest in targeting the activity in the oxytocin system to regulate social bonding. However, studies with exogenous administration of oxytocin face the caveats of its low stability, poor brain permeability and insufficient receptor ...
Michael C. Johnson, Jonathan A. Zweig, Yangmiao Zhang, Louis Nunez, Olga P. Ryabinina, Marcel Hibert, Andrey E. Ryabinin   +6 more
doaj   +1 more source

Impact of a Structured Caesarean Reduction Strategy on Perinatal Outcomes: A Retrospective Ecological Time‐Trend Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To evaluate the long‐term impact of a structured, multidisciplinary CS reduction strategy in a high‐complexity Italian hospital. Design Retrospective ecological time‐trend study. Setting Tertiary obstetric care Italian centre. Sample 28 577 deliveries, ≥ 22 weeks' gestation, from 2014 to 2024 were analysed.
Stefania Fieni, Giovanni Morganelli, Gabriella Maria Celora, Biancamaria Mastrandrea, Tullio Ghi   +4 more
wiley   +1 more source

Neuropeptide therapeutics to repress lateral septum neurons that disable sociability in an autism mouse model

Cell Reports Medicine
Summary: Confronting oxytocin and vasopressin deficits in autism spectrum disorders and rare syndromes brought promises and disappointments for the treatment of social disabilities.
Amélie M. Borie, Yann Dromard, Prabahan Chakraborty, Pierre Fontanaud, Emilie M. Andre, Amaury François, Pascal Colson, Françoise Muscatelli, Gilles Guillon, Michel G. Desarménien, Freddy Jeanneteau   +10 more
doaj   +1 more source

Effect of polychlorinated biphenyls on the secretion of oxytocin from luteal and granulosa cells in cow: possible involvement of glucocorticoid receptors

Veterinární Medicína, 2006
Polychlorinated biphenyls (PCBs) stimulate oxytocin secretion from bovine granulosa and luteal cells. Since oxytocin on the one hand is released from ovarian cells by cortisol and on the other hand PCBs can be bound by glucocorticoid receptors (GCr), we ...
J.J. Mlynarczuk, J. Kotwica
doaj   +1 more source

Vaginal Misoprostol Compared to Vaginal Dinoprostone for Induction of Labour: A Systematic Review and Meta‐Analysis

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Introduction Induction of labour is a common intervention. The prostaglandin dinoprostone is often used, but there is increasing evidence that misoprostol may be more effective without compromising safety. This review compares the efficacy and safety of vaginal misoprostol and vaginal dinoprostone.
Georgina Andersson, Benjamin Greenfield, Alexandra Hunt, Amr Malawany, Ben Luke Choo, William Dixon, David Lissauer, Andrew D. Weeks, Andrew Sharp, Gemma Clayton, Abi Merriel   +10 more
wiley   +1 more source

The evolution of oxytocin receptor signaling

Oxytocin is a neuromodulator and hormone that helps coordinate a variety of physiological and behavioral functions. Oxytocin exerts its diverse effects by binding to oxytocin receptors throughout the brain and the periphery, which initiates various signaling cascades. The location and distribution of oxytocin receptors can differ between species, which
Alina Irene Sartorius, Constantina Theofanopoulou, Daniel S Quintana   +2 more
openaire   +1 more source

Kaempferol Protects Intestinal Health in Chinese Forest Musk Deer Possibly by Regulating Intestinal Microbiota and Inhibiting the NF‐κB/NLRP3 Signaling Pathway

Integrative Zoology, EarlyView.
Kaempferol modulates the tryptophan metabolism pathway by increasing the abundances of Christensenellaceae R7 group, Bacteroides, and Blautia and reducing that of Rikenellaceae RC9 gut group, thereby significantly increasing the levels of ILA and IAA. This process inhibits the activation of NF‐κB/NLRP3 signaling pathway, reduces pro‐inflammatory factor
Xiangyu Liu, Zhanjun Ren, Xiuzhu Sun, Shuhui Wang   +3 more
wiley   +1 more source

Expression and activation of the oxytocin receptor in airway smooth muscle cells: Regulation by TNFα and IL-13

Respiratory Research, 2010
Background During pregnancy asthma may remain stable, improve or worsen. The factors underlying the deleterious effect of pregnancy on asthma remain unknown.
Siddiqui Salman, Zhao Hengjiang, Cooper Philip R, Baidouri Hasna, Sims Michael W, Keslacy Stefan, Jain Deepika, Liu Veronica, Li Katherine, Huang Chris, Syed Farhat, Amrani Yassine, Brightling Christopher E, Griswold Don, Li Lily, Panettieri Reynold A   +15 more
doaj   +1 more source

Comparative effectiveness, safety and acceptability of pharmacological and psychosocial interventions for the treatment of cannabis use disorder: A network meta‐analysis

Addiction, EarlyView.
Abstract Aim Our primary aim was to conduct a network meta‐analysis (NMA) for the effectiveness, safety and acceptability of all psychosocial interventions and all pharmacotherapies for cannabis use disorder (CUD). Methods We conducted a NMA of studies identified from two completed systematic reviews examining the effectiveness, safety and ...
Monika Halicka, Francesca Spiga, Tom P. Freeman, Suzanne Nielsen, Jelena Savović, Julian P. T. Higgins, Deborah M. Caldwell   +6 more
wiley   +1 more source