Results 81 to 90 of about 39,424 (213)

Oxytocin alleviates liver fibrosis via hepatic macrophages

JHEP Reports
Background & Aims: Previous studies demonstrated oxytocin treatment effectiveness in reducing mortality and reversing liver fibrosis in mice. However, the underlying mechanism remains obscure, given the absence of oxytocin receptor expression in ...
Xiangyu Zhai, Hao Zhang, Zhijia Xia, Mingkun Liu, Gang Du, Zhengchen Jiang, Huaxin Zhou, Dan Luo, Dandan Dou, Jingxin Li, Wei Wang, Xiaosong Li, Bin Jin   +12 more
doaj   +1 more source

Male-female comparison of vasomotor effects of circulating hormones in human intracranial arteries

The Journal of Headache and Pain
Background The purpose of this study was to examine whether there are sex differences in vasomotor responses and receptor localization of hormones and neuropeptides with relevance to migraine (vasopressin, oxytocin, estrogen, progesterone, testosterone ...
Jacob C. A. Edvinsson, Irena Grubor, Aida Maddahi, Lars Edvinsson   +3 more
doaj   +1 more source

Presystemic influences on thirst, salt appetite, and vasopressin secretion in the hypovolemic rat [PDF]

, 2006
Recent studies have shown that when dehydrated rats are given access to water or various concentrations of saline solution, they consume the same volume of fluid in an initial drinking bout (Hoffmann et al., 2006). Furthermore, there was a close relation
Smith, Carrie Alane
core  

Age-Dependent Effects of Oxytocin and Oxytocin Receptor Antagonists on Bladder Contractions: Implications for the Treatment of Overactive Bladder Syndrome

Biomedicines
Overactive bladder (OAB) is an age-related disorder characterised by unstable bladder contractions resulting in disruptive lower urinary tract symptoms (LUTS), thus creating a profound impact on an individual’s quality of life.
Masroor Badshah, Jibriil Ibrahim, Nguok Su, Penny Whiley, Ralf Middendorff, Michael Whittaker, Betty Exintaris   +6 more
doaj   +1 more source

Exogenous oxytocin administered to induce or augment labour is positively associated with quality of observed mother-infant bonding

Comprehensive Psychoneuroendocrinology
Oxytocin is a key hormone in the transition to motherhood. The maternal endogenous oxytocin system facilitates many physiological and biological adaptations, including breastfeeding, maternal wellbeing, and brain plasticity.
Hannah Edwards, Femke TA. Buisman-Pijlman, Adrian Esterman, Craig Phillips, Sandra Orgeig, Andrea Gordon   +5 more
doaj   +1 more source

Oxytocin Receptors on Calvarial Periosteal Innervation: Therapeutic Target for Post-Traumatic Headache?

Pharmaceutics
Objective: Following a mild traumatic brain injury (mTBI), the most prevalent and profoundly debilitating occurrence is the emergence of an acute and persistent post-traumatic headache (PTH), for which there are presently no approved treatments.
Vimala N. Bharadwaj, Michael Klukinov, Robert Paul Cowan, Nazanin Mahinparvar, David John Clark, David Clifford Yeomans   +5 more
doaj   +1 more source

Muscarinic receptor blockade with oxybutynin reduces spontaneous and induced uterine muscle contractions

Pregnancy
Objective The uterus and the bladder have striking physiologic and anatomic similarities. Anticholinergic medications are commonly used to treat “overactive bladder” by targeting M2 and M3 muscarinic receptors.
Anthony G. Visco, Zachary R. Visco, Chad A. Grotegut, Cristina Linde, Timothy Westfall, Friederike L. Jayes   +5 more
doaj   +1 more source

The Multifaceted Role of Oxytocinergic System and OXTR Gene

Global Medical Genetics
The article explores the multifaceted role of the neuropeptide oxytocin in human behavior and its connection to the oxytocin receptor (OXTR) gene. Oxytocin, produced in specific brain nuclei, is implicated in emotional, social, and maternal behaviors ...
Rakibul Hasan
doaj   +1 more source

Oxytocin Increases Generosity in Humans [PDF]

Human beings routinely help strangers at costs to themselves. Sometimes the help offered is generous offering more than the other expects. The proximate mechanisms supporting generosity are not well-understood, but several lines of research suggest a ...
Ahmadi, Sheila, Stanton, Angela A., Zak, Paul J.   +2 more
core   +1 more source

Limbic oxytocin receptor expression alters molecular signaling and social avoidance behavior in female prairie voles (Microtus ochrogaster)

Frontiers in Neuroscience
IntroductionThe social defeat paradigm is the most representative animal model to study social anxiety disorder (SAD) and its underlying neuronal mechanisms.
Lina K. Nerio-Morales, Arjen J. Boender, Larry J. Young, Marisol R. Lamprea, Adam S. Smith, Adam S. Smith   +5 more
doaj   +1 more source