Results 21 to 30 of about 86,670 (263)

Progesterone Regulation of the Progesterone Receptor in Rat Gonadotropes* [PDF]

open access: yesEndocrinology, 2000
For rat pituitary cells, progesterone receptor (PR) protein localizes to gonadotropes and PR messenger RNA is induced by E2 and rapidly but transiently down-regulated by progesterone. Here we quantitatively establish the down-regulatory effect of progesterone on PR protein and evaluate possible mechanisms.
J L, Turgeon, D W, Waring
openaire   +2 more sources

A novel therapeutic approach for treatment of catamenial epilepsy

open access: yesNeurobiology of Disease, 2018
Many women with epilepsy experience perimenstrual seizure exacerbation, referred to as catamenial epilepsy. There is no effective treatment for this condition, proposed to result from withdrawal of neurosteroid-mediated effects of progesterone.
Suchitra Joshi   +5 more
doaj   +1 more source

Progesterone receptors, their isoforms and progesterone regulated transcription [PDF]

open access: yesMolecular and Cellular Endocrinology, 2012
This review discusses mechanisms by which progesterone receptors (PR) regulate transcription. We examine available data in different species and tissues regarding: (1) regulation of PR levels; and (2) expression profiling of progestin-regulated genes by total PRs, or their PRA and PRB isoforms.
Britta M, Jacobsen, Kathryn B, Horwitz
openaire   +2 more sources

Morphological Characteristics and Expression of Estrogen and Progesterone Receptors in the Canine Endometrium During the Estrus Cycle, Cystic Endometrial Hyperplasia and Pyometra

open access: yesActa Veterinaria, 2018
The estrus cycle of bitches is divided into four phases: proestrus, estrus, diestrus and anestrus, during which different morphological changes, and also cyclic changes of estrogen and progesterone receptors are present.
Marinković Darko   +4 more
doaj   +1 more source

Progesterone signaling mechanisms in brain and behavior

open access: yesFrontiers in Endocrinology, 2012
Steroid hormone, progesterone, modulates neuroendocrine functions in the central nervous system resulting in alterations in physiology and behavior.
Shaila eMani, Mario G Oyola
doaj   +1 more source

Membrane progesterone receptor beta (mPRβ/Paqr8) promotes progesterone-dependent neurite outgrowth in PC12 neuronal cells via non-G protein-coupled receptor (GPCR) signaling

open access: yesScientific Reports, 2017
Recently, sex steroid membrane receptors garnered world-wide attention because they may be related to sex hormone-mediated unknown rapid non-genomic action that cannot be currently explained by their genomic action via nuclear receptors.
Mayu Kasubuchi   +8 more
doaj   +1 more source

Reproductive functions of the progesterone receptor

open access: yesJournal of the Society for Gynecologic Investigation, 2000
The steroid hormone progesterone plays a central role in the reproductive events associated with pregnancy establishment and maintenance. Physiological effects of progesterone are mediated by interaction of the hormone with specific intracellular progesterone receptors (PRs) that are expressed as two protein isoforms, PR-A and PR-B. Both proteins arise
Conneely, O.M.   +4 more
openaire   +3 more sources

Overexpression of Androgen, Oestrogen and Progesterone Receptors in Skin Lesions of Becker’s Naevus

open access: yesActa Dermato-Venereologica, 2018
Becker’s naevus is androgen-dependent. The aim of this study was to investigate whether oestrogen and progesterone receptors are involved in this disorder.
Ping Sheng   +6 more
doaj   +1 more source

Estrogen and Progesterone Receptors in Human Colorectal Tumour Cells (Study of 70 Cases)

open access: yesThe International Journal of Biological Markers, 1988
Estrogen and progesterone receptors were studied in 70 cases of human colorectal cancer by a cytochemical technique. 28.5% of the cases were estrogen-receptor positive and 42.8% progesterone-receptor positive.
G. Bracali   +5 more
doaj   +1 more source

Rodent Models of Non-classical Progesterone Action Regulating Ovulation

open access: yesFrontiers in Endocrinology, 2017
It is becoming clear that steroid hormones act not only by binding to nuclear receptors that associate with specific response elements in the nucleus but also by binding to receptors on the cell membrane. In this newly discovered manner, steroid hormones
Melinda A. Mittelman-Smith   +3 more
doaj   +1 more source

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