Results 131 to 140 of about 150,073 (296)

Neurosteroids in pain management: A new perspective on an old player [PDF]

, 2018
Covey, Douglas F, Jevtovic-Todorovic, Vesna, Joksimovic, Sonja L, Todorovic, Slobodan M   +3 more
core   +2 more sources

Within‐Person Changes in Daily Ovarian Hormone Levels Influence Genetic Effects on Emotional Eating in Women

International Journal of Eating Disorders, EarlyView.
ABSTRACT Introduction Ovarian hormones (i.e., estradiol, progesterone) show robust phenotypic associations with binge eating and related behaviors (e.g., emotional eating) in females. Recent research suggests these associations may be due to ovarian hormone effects on genetic and environmental influences on dysregulated eating. However, no research has
Megan E. Mikhail, Kristen M. Culbert, Pamela K. Keel, S. Alexandra Burt, Cheryl L. Sisk, Alexander Johnson, Steven Boker, Micheal C. Neale, Kelly L. Klump   +8 more
wiley   +1 more source

Estrogen and Progesterone Exhibit Distinct Yet Coordinated Roles in the Regulation of Tendon Extracellular Matrix Remodeling. [PDF]

J Orthop Res
ABSTRACT Remodeling of the extracellular matrix (ECM) is required for the proper healing, strengthening, and maintenance of tendon tissue. There are well‐documented sex differences in tendon injury rates and healing outcomes, often attributed to either innate differences in tissue structure and resident cell signaling or the influence of sex hormones ...
Sander AM, Connizzo BK.
europepmc   +2 more sources

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Identifying Gene Predictors of Chemicals Linked With Breast Cancer: A Machine Learning Analysis of MCF7 Cellular Transcriptomic Screening Data

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT Breast cancer is the most prevalent cancer in women and has been linked to exposure to environmental chemicals. However, many chemicals have not been evaluated for relationships with this outcome. In this study, we analyzed RNA sequencing data from human breast cancer‐derived MCF7 cells exposed to hundreds of individual chemicals.
Lauren E. Koval, Richard Judson, Julia E. Rager   +2 more
wiley   +1 more source

Origin and diversification of steroids: Co-evolution of enzymes and nuclear receptors [PDF]

, 2010
Recent sequencing of amphioxus and sea urchin genomes has provided important data for understanding the origins of enzymes that synthesize adrenal and sex steroids and the receptors that mediate physiological response to these vertebrate steroids ...
Michael E. Baker
core   +1 more source

Toward a working definition of ketogenic diet resistance in GLUT1 deficiency syndrome

Epileptic Disorders, EarlyView.
Abstract Objective The ketogenic diet (KD) is the standard treatment for glucose transporter type 1 deficiency syndrome (GLUT1‐DS), typically yielding seizure reduction and cognitive/motor gains. However, a small subset of patients shows limited or no clinical benefit.
Raffaele Falsaperla, Vincenzo Sortino, Gerhard Josef Kluger, Thomas Herberhold, Andrea Rüegger, Pasquale Striano, Martino Ruggieri, Joerg Klepper, Georgia Ramantani   +8 more
wiley   +1 more source

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Human Endometriosis Tissue Microarray Reveals Site-specific Expression of Estrogen Receptors, Progesterone Receptor, and Ki67. [PDF]

Appl Immunohistochem Mol Morphol, 2019
Colón-Caraballo M, García M, Mendoza A, Flores I.   +3 more
europepmc   +1 more source

Wearable biosensors based on molecularly imprinted polymers

FlexMat, EarlyView.
Wearable biosensors based on molecularly imprinted polymers (MIPs) provide real‐time, non‐invasive monitoring of key biomarkers. This review highlights the research advances on MIPs‐based biosensors with enhanced selectivity, stability, and adaptability in flexible sensing platforms.
Xiangnan Li, Rongqi Ou, Zhen Yuan, Yuanjing Lin   +3 more
wiley   +1 more source