Results 191 to 200 of about 2,548,577 (237)

Receptors for progesterone

Gynecologic Oncology, 1974
Abstract Coordinated estrogen- and progesterone-induced changes regulate biological functions of the endometrium. The uterine deciduoma reaction is used as a model in defining the mechanism of the progesterone-induced endometrial transformations. Uterine progesterone concentrations were determined by radioimmunoassay during three critical periods ...
B R, Rao, W G, Wiest
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Progesterone receptor coactivators

Steroids, 2000
Progesterone action is mediated by intracellular progesterone receptors that regulate target gene transcription. Recently, numerous proteins termed coactivators have been identified that are recruited by the liganded progesterone receptor and enhance receptor-dependent transactivation.
B G, Rowan, B W, O'Malley
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Progesterone and progesterone receptors in reptiles

General and Comparative Endocrinology, 2002
The role of progesterone (P) has been most extensively studied in the female reproductive tissues (ovary, reproductive tract, mammary gland) and in the brain, in which it is an important regulator and modulator in conjunction with estradiol (E). In nonmammalian vertebrate species, less work has been done on P metabolites involved in ovulation.
Noemí, Custodia-Lora, Ian P, Callard
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Progesterone-Progestin Receptors

1974
A correlation between binding to the progestin-specific uterine cytosol receptor and with well-defined facets of progesterone action was established. Structurally similar derivatives of norprogesterone and nortestosterone were compared. Binding was measured in vitro by determining their competitive effect on the progestin-tagged uterine cytosol ...
J P, Raynaud, D, Philibert, G, Azadian-Boulanger   +2 more
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Progesterone antagonists and progesterone receptor modulators

Expert Opinion on Investigational Drugs, 2003
Since the discovery of the antiprogestin RU 486 (mifepristone), other compounds have been synthesised that function as pure progesterone antagonists or progesterone receptor modulators. The latter are mixed agonists-antagonists. Mifepristone is usually used to terminate pregnancy but these compounds have numerous other applications in female healthcare.
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Progesterone Receptor Signaling Mechanisms

Journal of Molecular Biology, 2016
Progesterone receptor (PR) is a master regulator in female reproductive tissues that controls developmental processes and proliferation and differentiation during the reproductive cycle and pregnancy. PR also plays a role in progression of endocrine-dependent breast cancer.
Sandra L, Grimm, Sean M, Hartig, Dean P, Edwards   +2 more
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Selective progesterone receptor modulators

Current Opinion in Obstetrics & Gynecology, 2014
Review of recent data from clinical trials and descriptions of endometrial morphology with administration of selective progesterone receptor modulators (SPRMs).Recent reports concerning administration of SPRMs, specifically the efficacy of ulipristal acetate in reducing fibroid size and rapid control of menstrual blood loss, have renewed clinical ...
Lucy H R, Whitaker, Alistair R W, Williams, Hilary O D, Critchley   +2 more
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Novel Mechanisms of Progesterone Antagonists and Progesterone Receptor

Journal of the Society for Gynecologic Investigation, 2000
The progesterone receptor (PR), as a member of the nuclear receptor superfamily of ligand-dependent transcription factors, activates gene transcription through binding to specific palindromic progesterone response elements (PRE) in the promoter region of progestin-responsive genes.
D P, Edwards, S A, Leonhardt, E, Gass-Handel   +2 more
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