Results 61 to 70 of about 151,487 (293)

Therapeutic effects of progesterone and its metabolites in traumatic brain injury may involve non-classical signaling mechanisms

Frontiers in Neuroscience, 2013
Traumatic brain injury is an important and costly medical problem for which no clinically proven treatment currently exists. Studies in rodents and humans have shown beneficial effects of progesterone (P4) on both mortality and functional outcomes ...
Paul S. Cooke
doaj   +1 more source

Special aspects of steroid hormone receptors’ expression in cases of cervical intraepithelial neoplasia depending on the papillomavirus infection progression in women with infertility

Regulatory Mechanisms in Biosystems, 2020
The relevance of the study is contingent on insufficient study of the correlation between the reception of uterine cervix steroid hormones in cases of cervical intraepithelial neoplasia (CIN) and the level of human papilloma virus load in women with ...
E. O. Kindrativ, N. Y. Chuiko, O. Y. Zhurakivska   +2 more
doaj   +1 more source

End‐to‐End Sensing Systems for Breast Cancer: From Wearables for Early Detection to Lab‐Based Diagnosis Chips

Advanced Materials Technologies, EarlyView.
This review explores advances in wearable and lab‐on‐chip technologies for breast cancer detection. Covering tactile, thermal, ultrasound, microwave, electrical impedance tomography, electrochemical, microelectromechanical, and optical systems, it highlights innovations in flexible electronics, nanomaterials, and machine learning.
Neshika Wijewardhane, Lyn I. Jones, Richard M. Martin, Helen Winter, Faezeh Arab Hassani   +4 more
wiley   +1 more source

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

Advanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang, He Huang, Hongliang Dong, Qiang Ma, Hongyan Jin   +4 more
wiley   +1 more source

Characterization of membrane-associated non-genomic progesterone receptors in cattle bull spermatozoa

Indian Journal of Animal Sciences
The present study aimed to examine the molecular existence of the non-genomic progesterone receptors (P4) and their location in Hariana bull spermatozoa.
VIKAS SACHAN, SOUMEN CHOUDHURY, DILIP K SWAIN, ANUJ KUMAR, ATUL SAXENA, PRATISHTHA SHARMA, AVANEESH KUMAR SINGH   +6 more
doaj   +1 more source

Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development

Advanced Science, EarlyView.
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu, Yanzhi Feng, Qingqing Zhu, Ting Jiang, Yueyue Gao, Kebing Nie, Xianan Tang, Ying Chen, Dianxing Hu, Xudan Yang, Shixuan Wang, Meng Wu, Jinjin Zhang   +12 more
wiley   +1 more source

A Study of Hormonal Receptors in Esophageal Carcinoma: Northeast Indian Tertiary Cancer Center Study

South Asian Journal of Cancer, 2020
Background Esophageal cancers, both squamous cell and adenocarcinoma, have poor outcomes with high morbidity and mortality. Our hospital-based registry for the year 2017 to 2018 showed that esophageal cancer constituted 22.7% of annual caseload.
Deepjyoti Kalita, Srinivas Bannoth, Joydeep Purkayastha, Abhijit Talukdar, Gaurav Das, Pritesh Singh   +5 more
doaj   +1 more source

Early Radiation Therapy Response Assessment Using Multi‐Scale Photoacoustic Imaging

Advanced Science, EarlyView.
Tomographic and mesoscopic photoacoustics capture intratumoural features of radioresistance and response. ABSTRACT There is a critical unmet clinical need to identify biomarkers that predict and detect radiation therapy (RT) response in cancer. Using the unique capabilities of multi‐scale photoacoustic imaging (PAI) to depict tumor oxygenation and ...
Thierry L. Lefebvre, Mariam‐Eleni Oraiopoulou, Ellie V. Bunce, Thomas R. Else, Lorna C. Wright, Monika A. Golinska, Lina Hacker, Cara Brodie, Steven Kupczak, Yi Cheng, Lisa Young, Paul W. Sweeney, Sarah E. Bohndiek   +12 more
wiley   +1 more source

Role of lactobacilli and lactoferrin in the mucosal cervicovaginal defense [PDF]

, 2018
Human lactoferrin is an iron-binding glycoprotein present at high concentrations in breast milk and colostrum. It is produced by many exocrine glands and widely distributed in a variety of body fluids.
Aagaard, Abramov, Agerberth, Aldunate, Alexander, Allsworth, Anahtar, Ando, Appelmelk, Aroutcheva, Ashida, Baker, Baranger, Beigi, Berlutti, Berlutti, Berlutti, Bradshaw, Bradshaw, Britigan, Brooks, Brotman, Bullen, Byrne, Caccavo, Cauci, Cherpes, Cole, Cole, Conti, Corbin, Corbishley, Cutone, Cutone, De Gregorio, Deese, Delgado-Rizo, Drannik, Elass, Ericksen, Eschenbach, Eslami, Frioni, Fritsch, Gajer, He, He, Hearps, Hedges, Hein, Hemalatha, Hickey, Hiemstra, Hill, Hill, Hudić, Hummelen, Jakobsson, Judd, Kaushic, Kelver, Klebanoff, Kohlhoff, Kościuczuk, Lamont, Larsen, Legrand, Legrand, Leitch, Maggi, Marrazzo, Martin, Martin, Mastromarino, Mastromarino, Mastromarino, Meijerink, Michieli, Moberg, Morrison, Morrison, Nardis, Ness, Niyonsaba, Olmsted, Olmsted, Omata, Ong, O’Hanlon, Paesano, Paesano, Paesano, Paesano, Paesano, Pazgier, Peipert, Peipert, Petrova, Pino, Puddu, Quayle, Rampersauda, Raulston, Ravel, Ravel, Redondo-Lopez, Reghunathan, Rizzo, Rizzo, Roberton, Rosa, Rönnqvist, Santiago, Santiago, Sarkar, Sessa, Shakibaei, Shust, Singh, Singh, Spadaro, Spear, Spurbeck, Srinivasan, Srinivasan, Stallmann, Straub, Stríz, Suzuki, Tachedjian, Teng, Teng, Teng, Tuyama, Valenti, Valenti, Valenti, Valore, Van de Wijgert, Vargas-Villavicencio, Vielfort, Vitali, Walther-António, Ward, Weinberg, Wiesenfeld, Wiesner, Wilson, Wilson, Wilson, Wira, Wira, Wira, Wira, Wu, Yamamoto, Zhou   +156 more
core   +2 more sources

A Biomarker‐Driven Ovary–Endometrium Organ‐on‐a‐Chip Mimicking 3D Multicellular Complexity and Menstrual Cyclicity for Predicting Reproductive Toxicity

Advanced Science, EarlyView.
We present a dual‐organ, biomarker‐integrated ovaryendometrium organ‐on‐a‐chip that recapitulates 3D tissue complexity, menstrual cycle dynamics, and hormonal crosstalk. This platform enables real‐time, cell‐typespecific fluorescent readouts of reproductive toxicity using ANGPTL4 and SERPINB2 as early‐response reporters.
Soo‐Rim Kim, Eun‐kyung Min, Choon‐Mi Lee, Chan Hum Park, Byung‐Chul Oh, YunJae Jung, In‐Sun Hong   +6 more
wiley   +1 more source