Progesterone receptor modulators for endometriosis [PDF]
Endometriosis is defined as the presence of endometrial tissue (glands and stroma) outside the uterine cavity. This condition is oestrogen-dependent and thus is seen primarily during the reproductive years. Owing to their antiproliferative effects in the endometrium, progesterone receptor modulators (PRMs) have been advocated for treatment of ...
Jing, Fu +6 more
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CLINICAL CHARACTERISTICS OF BREAST CANCER WITH STEROID RECEPTORS EXPRESSION AND HER2 AMPLIFICATION
Since the middle of the previous century the heterogeneity of breast cancer became absolutely evident. This assumption was historically based on differences in clinical behavior and sensitivity to therapy.
F. V. Moiseenko +9 more
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Progesterone receptor modulators [PDF]
This letter to the editor discusses the use the primary mechanism of action and the effectiveness of progesterone receptor modulator a ulipristal acetate.
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Transcriptional and posttranscriptional regulation of human androgen receptor expression by androgen. [PDF]
Autoregulation is a control mechanism common to several proteins of the steroid/thyroid hormone receptor superfamily. In this work the effect of androgens and antiandrogens on the expression of the human androgen receptor (hAR) in prostate and breast ...
Blasschke, Dorothea +4 more
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The Role of the Brain in the Pathogenesis and Physiology of Polycystic Ovary Syndrome (PCOS). [PDF]
Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disorder, affecting at least 10% of women of reproductive age. PCOS is typically characterized by the presence of at least two of the three cardinal features of hyperandrogenemia (high ...
Coutinho, Eulalia A +1 more
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Role of lactobacilli and lactoferrin in the mucosal cervicovaginal defense [PDF]
Human lactoferrin is an iron-binding glycoprotein present at high concentrations in breast milk and colostrum. It is produced by many exocrine glands and widely distributed in a variety of body fluids.
Aagaard +156 more
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The paradox of pregnancy : an update on the immunology of early pregnancy [PDF]
Pregnancy is an altered physiological state where an organism essentially foreign to the individual carrying it, grows, develops and at an appropriate time probably initiates a series of signals which lead to its safe expulsion from the woman's body. The
Formosa, Mark
core
Sex steroids regulate skin pigmentation through nonclassical membrane-bound receptors
The association between pregnancy and altered cutaneous pigmentation has been documented for over two millennia, suggesting that sex hormones play a role in regulating epidermal melanocyte (MC) homeostasis.
Christopher A Natale +8 more
doaj +1 more source
Comparison of upper body strength gains between men and women after 10 weeks of resistance training [PDF]
Resistance training (RT) offers benefits to both men and women. However, the studies about the differences between men and women in response to an RT program are not conclusive and few data are available about upper body strength response.
Bottaro, Martim +5 more
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PGR (progesterone receptor) [PDF]
The progesterone receptor gene PGR is located on 11q22.1. The functional gene has 8 exons and 7 introns; the transcript is translated into 933 residues. The protein occurs as three isoforms viz. PR-A; PR-B; PR-C and 11 splice variants. PR-A and PR-B are structurally similar.
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