Results 201 to 210 of about 571,577 (250)

Role of Astrocytes in Central Respiratory Control. [PDF]

Cells
Okada Y, Fukushi I, Yokota S, Takeda K, Umeda A, Pokorski M, Onimaru H.   +6 more
europepmc   +1 more source

Lack of Oncomodulin Increases ATP-Dependent Calcium Signaling and Susceptibility to Noise in Adult Mice. [PDF]

eNeuro
Yang Y, Jeng JY, Murtha K, Climer LK, Ceriani F, Sese WD, Hornak AJ, Sleiman KC, Stahl I, Liberman MC, Marcotti W, Simmons DD.   +11 more
europepmc   +1 more source

The long march towards testing the adenosine receptor agonism hypothesis for human cerebroprotection: The story of the A₁R/A₃R receptor agonist AST-004. [PDF]

Purinergic Signal
Liston TE, Korinek WS, Jacobson KA, Lechleiter JD.   +3 more
europepmc   +1 more source

PET Imaging of Purinergic Receptors

, 2020
Over the recent years, interest in the purinergic signaling system has sparked in the field of positron emission tomography (PET). Purinergic receptors play key roles in physiological and pathological processes, although the exact role in these processes is not always fully understood.
Janssen, Bieneke, Vugts, Danielle J., Windhorst, Albert D.   +2 more
openaire   +4 more sources

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Platelet purinergic receptors

Current Opinion in Pharmacology, 2003
Activation of P2Y(1) and P2Y(12) receptors, through secreted ADP that is stimulated by agonists such as thrombin, thromboxane and collagen, is a major mechanism of platelet activation. P2X(1) receptors also participate in platelet shape change and potentiation of calcium mobilization.
Satya P, Kunapuli, Robert T, Dorsam, Soochong, Kim, Todd M, Quinton   +3 more
openaire   +2 more sources

Bladder Purinergic Receptors^a

Annals of the New York Academy of Sciences, 1990
In rabbits the contractile response of the urinary bladder is only partially due to cholinergic innervation since atropine does not completely block neuronally mediated contractions. In the human bladder this atropine resistance is controversial with some reporting atropine resistance in vitro while others have stated that the atropine resistance is ...
M R, Ruggieri, K E, Whitmore, R M, Levin
openaire   +2 more sources

Signaling at Purinergic P2X Receptors

Annual Review of Physiology, 2009
P2X receptors are membrane cation channels gated by extracellular ATP. Seven P2X receptor subunits (P2X1-7) are widely distributed in excitable and nonexcitable cells of vertebrates. They play key roles in inter alia afferent signaling (including pain), regulation of renal blood flow, vascular endothelium, and inflammatory responses.
Surprenant, Annmarie, Alan North, R.
openaire   +3 more sources

Purinergic receptors in airway hydration

Biochemical Pharmacology, 2021
Airway epithelial purinergic receptors control key components of the mucociliary clearance (MCC), the dominant component of pulmonary host defense. In healthy airways, the periciliary liquid (PCL) is optimally hydrated, thus acting as an efficient lubricant layer over which the mucus layer moves by ciliary force.
Eduardo R. Lazarowski, Richard C. Boucher   +1 more
openaire   +2 more sources

Purinergic receptors, prostacyclin and atherosclerosis

Pharmacological Research, 1992
Over the last decade, evidence has been provided that endothelial cells have a metabolic function in order to maintain blood vessel homeostasis. The endothelium releases relaxing and contracting factors in response to endogenous or exogenous substances such as acetylcholine, calcimycine, adenosine 5'triphosphate (ATP), bradykinin, arachidonic acid and ...
RAGAZZI, EUGENIO, CHINELLATO A.
openaire   +2 more sources