Results 141 to 150 of about 103,177 (262)

Dopamine and serotonin cotransmission filters striatonigral synaptic activity via 5-HT1B receptor activation. [PDF]

Sci Adv
Molinari M, Aaltonen A, Lieberman OJ, Sulzer D, Santini E, Borgkvist A.   +5 more
europepmc   +1 more source

Serotonin (5-HT1A) receptor; serotonin (5-HT3) receptor [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Host–microbiota interaction drives 5‐hydroxyindole‐3‐acetic acid production to promote linear growth in infant mice

iMetaOmics, EarlyView.
This study discovered that Lactiplantibacillus plantarum Hi188 promoted linear growth in postweaning mice. Transcriptomic analysis, untargeted metabolomics, and in vitro experiments showed that the elevated levels of 5‐hydroxyindole‐3‐acetic acid (5‐HIAA) activated the hepatic aryl hydrocarbon receptor (AhR) and subsequently promoted insulin‐like ...
Yongmei Yang, Jing Yang, Weiyao Zhang, Linghao Zhou, Chenxu Zhu, Xuguang Zhang, Yuejian Mao, Meiling Zhang   +7 more
wiley   +1 more source

LPS-Induced Neuroinflammation Increases Serotonin-Evoked Activity of Trigeminal Afferents and Aggravates Mechanical Allodynia and Photophobic Behavior in Rat Migraine Model. [PDF]

Int J Mol Sci
Svitko S, Ermakova E, Gilizhdinova K, Bogatova K, Gaifutdinova N, Nurmieva D, Nevsky E, Ananev A, Yakovleva O, Sufianov A, Sufianova GZ, Baev A, Shaidullova K, Rizvanov A, Yakubova A, Sitdikova G.   +15 more
europepmc   +1 more source

Weizmannia coagulans XY2 Mitigates Copper Neurotoxicity via Gut–Brain Axis Modulation of Tryptophan Metabolism and Oxidative‐Inflammatory Crosstalk

iMetaOmics, EarlyView.
Copper interferes with tryptophan metabolism and 5‐HT levels by modulating intestinal flora. Intestinal barrier breakdown and inflammatory response trigger nerve damage under copper exposure. W. coagulans XY2 alleviates copper‐induced neurotoxicity by targeting a multi‐dimensional “tryptophan metabolism‐antioxidant defense‐gut‐brain axis” network.
Yufang Gao, Xiaodong Zheng, Fujie Yan
wiley   +1 more source

G Protein-Coupled Receptors in Irritable Bowel Syndrome: Mechanisms and Therapeutic Opportunities. [PDF]

Int J Mol Sci
Zhu Z, Liu Z, He Y, He X, Zheng W, Jiang M.   +5 more
europepmc   +1 more source

White Matter Dysfunction and Neurotransmitter Basis Underlying the Freezing of Gait in Parkinson's Disease

iNew Medicine, EarlyView.
In the freezing of gait in Parkinson's disease, white matter shows decreased local activity but increased functional connectivity. These distinct dysfunctions are uniquely associated with specific neurotransmitter systems (GABA, dopamine, etc.), mapping a new neurochemical basis for this debilitating symptom. ABSTRACT Freezing of gait (FOG) is a severe
Pingping Liu, Jinmei Sun, Lili Hu, Xin Chen, Jinying Han, Liuzhenxiong Yu, Siyu Fan, Rong Ye, Kai Wang, Gong‐Jun Ji, Panpan Hu   +10 more
wiley   +1 more source

Molecular Mechanisms of Emerging Antidepressant Strategies: From Ketamine to Neuromodulation. [PDF]

Int J Mol Sci
Kowalczyk M, Aebisher D, Szpara J, Czech S, Bartusik-Aebisher D, Henrykowska G.   +5 more
europepmc   +1 more source

Integrating the Gestalt Model of Self With Psychedelic‐Assisted Psychotherapy

The Journal of Humanistic Counseling, EarlyView.
ABSTRACT This theoretical integration paper employs a conceptual analysis methodology to synthesize the Gestalt model of self‐as‐process with Psychedelic Somatic Interactional Psychotherapy (PSIP). Unlike traditional psychedelic therapy models that defer therapeutic engagement to postsession integration, PSIP emphasizes an active, directive therapeutic
Travis R. Fox
wiley   +1 more source

Serotonin inhibits the influx of iron into cells by decreasing the expression of SLC11A2 in Caco-2 cells. [PDF]

Biomed Rep
Sugino Y, Ameku M, Kawanishi N, Nonen S.
europepmc   +1 more source