Results 181 to 190 of about 2,570,395 (251)
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Serotonin, serotonin receptors, serotonin receptor subtype agonists and pain
Pain, 1990J. Pascual
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Tryptamine and Serotonin Receptors
Nature, 1962A RECENT communication by Vane et al. entitled “Tryptamine Receptors in the Central Nervous System”1 concluded, on the basis of indirect evidence, that the receptors for tryptamine and for serotonin (5-hydroxytryptamine) were the same. Because the authors neglected to mention some earlier evidence of a more direct kind which showed clearly that certain
E Shaw, D. W. Woolley
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Serotonin and serotonin receptors in the central auditory system [PDF]
Otolaryngology–Head and Neck Surgery, 1994 Immunohistochemical and ligand‐binding techniques were used to visualize the neurotransmitter serotonin and one of its receptors, the 5‐HT1A subtype, in auditory nuclei of the brainstem. Serotonergic fibers and terminal endings were found in all auditory nuclei extending from the cochlear nucleus to the inferior colliculus, including the superior ...
Ann M. Thompson +3 more
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Palmitoylation of serotonin receptors
Biochemical Society Transactions, 2013The covalent attachment of palmitic acid to one or more cysteine residues (S-palmitoylation) is a widespread modification of signalling proteins. With the finding that palmitoylation is a dynamic process, it is now widely accepted that repeated cycles of palmitoylation/depalmitoylation could be involved in the regulation of multiple signalling ...
Evgeni Ponimaskin, Nataliya Gorinski
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Subtypes of Receptors for Serotonin
Annual Review of Pharmacology and Toxicology, 1990Interest in the physiological functions of 5-hydroxytryptamine (5-HT; seroto nin) has increased steadily since its discovery in the intestine (1) and in serum (2). Its identification in brain in the early 1950s (3), followed a decade later by the initial studies of its distribution in brain by histofluorescence (4), stimulated investigations of the ...
Alan Frazer +2 more
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Serotonin and Serotonin Receptors in Hallucinogen Action
2010Abstract Hallucinogens (psychedelics) are substances that induce profound changes in perception and cognition. The closely related 3,4-methylenedioxymethamphetamine (MDMA) produces euphoria and a feeling of empathy, with minimal sensory distortion. Both of these classes of substances produce their effects by interacting with the serotonergic system ...
Adam L. Halberstadt, David E. Nichols
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1993
The fact that nearly all known serotonin receptor subtypes are single subunit proteins, members of the same gene superfamily (the G protein-coupled receptor or 7TM superfamily) and that most are intronless genes has helped accelerate the cloning of this receptor family.
L E Schechter +7 more
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The fact that nearly all known serotonin receptor subtypes are single subunit proteins, members of the same gene superfamily (the G protein-coupled receptor or 7TM superfamily) and that most are intronless genes has helped accelerate the cloning of this receptor family.
L E Schechter +7 more
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Oligomerization of Dopamine and Serotonin Receptors
Neuropsychopharmacology, 2000Until recently, it has largely been assumed that G protein-coupled receptors (GPCRs) function as monomeric entities. However, over the past few years, we and others have documented that GPCRs can form dimers and oligomers, leading to a re-evaluation of the mechanisms thought to mediate GPCR function.
Tuan V. Nguyen +7 more
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1997
In terms of its anatomical distribution, serotonin is strategically placed to affect the cerebral vasculature as it is located on both sides of the neuronal–vascular axis. The serotonin system consists of clusters of neurons containing 5-HT that have extensive projections to virtually all areas of the brain.
Gilles Bonvento, Eric T. MacKenzie
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In terms of its anatomical distribution, serotonin is strategically placed to affect the cerebral vasculature as it is located on both sides of the neuronal–vascular axis. The serotonin system consists of clusters of neurons containing 5-HT that have extensive projections to virtually all areas of the brain.
Gilles Bonvento, Eric T. MacKenzie
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