Neuropharmacological classification of antidepressant agents based on their mechanisms of action
Archives of Medicine and Health Sciences, 2018 The currently available clinical antidepressants can be classified into 13 different classes based on their mechanisms of action. These basic pharmacological concepts thoroughly elucidate and unravel the therapeutic actions and side effects of the wide ...
Olumuyiwa John Fasipe
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Function and distribution of 5-HT2 receptors in the honeybee (Apis mellifera). [PDF]
PLoS ONE, 2013 BACKGROUND: Serotonin plays a pivotal role in regulating and modulating physiological and behavioral processes in both vertebrates and invertebrates. In the honeybee (Apis mellifera), serotonin has been implicated in division of labor, visual processing,
Markus Thamm +6 more
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Alcohol addiction: a molecular biology perspective. [PDF]
, 2015 Alcohol misuse represents worldwide an important risk factor for death and disability. Excessive alcohol consumption is widely diffused in different ethnicities and alcohol use is part of the lifestyle of both young and old people.
Ferraguti, Giampiero +2 more
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Molecular Biology of Serotonin Receptors [PDF]
Obesity Research, 1995 AbstractOver the last several years the use of molecular cloning technology has revealed a vast diversity among serotonin (5‐HT)receptors, where by what was previously thought to be a family of three pharmacologically defined classes of 5‐HT receptors is actually composed of seven distinct subfamilies designated 5‐HT1–7.
D L Nelson +4 more
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Receptors and Other Signaling Proteins Required for Serotonin Control of Locomotion in Caenorhabditis elegans [PDF]
Genetics, 2012 A better understanding of the molecular mechanisms of signaling by the neurotransmitter serotonin is required to assess the hypothesis that defects in serotonin signaling underlie depression in humans.
Güliz Gürel +4 more
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Preclinical discovery of duloxetine for the treatment of depression [PDF]
, 2012 Introduction: Affective disorders, including major depressive disorder (MDD), are among the most severely disabling mental disorders, and in many cases areIntroduction: Affective disorders, including major depressive disorder (MDD), are among the most ...
Berrocoso Domínguez, Esther María +4 more
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Therapeutic Potential of 5-HT2C Receptor Ligands
The Scientific World Journal, 2010 Serotonin 2C receptors are G protein-coupled receptors expressed by GABAergic, glutamatergic, and dopaminergic neurons. Anatomically, they are present in various brain regions, including cortical areas, hippocampus, ventral midbrain, striatum, nucleus ...
Nanna H. Jensen +2 more
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Interactions between the neuromodulatory systems and the amygdala: exploratory survey using the Allen Mouse Brain Atlas. [PDF]
, 2013 Neuromodulatory systems originate in nuclei localized in the subcortical region of the brain and control fundamental behaviors by interacting with many areas of the central nervous system.
Krichmar, Jeffrey L, Zaldivar, Andrew
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Role of 5-HT7 receptors in the immune system in health and disease
Molecular Medicine, 2019 In mammalians, serotonin (5-HT) has critical roles in the central nervous system (CNS), including mood stability, pain tolerance, or sleep patterns.
Alejandro Quintero-Villegas +1 more
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Hallucinogens: mechanisms and medical complications [PDF]
, 2013 Thesis (M.A.)--Boston UniversityHallucinogens are drugs that alter consciousness by distorting primarily auditory and visual perception but they can affect any sensory system. Hallucinogens also affect judgment, orientation, memory, or emotion.
Chan, Ryan Harry Alexander
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