Results 31 to 40 of about 197,813 (313)
Health Technology Assessment, 2023 Background Antidepressants are commonly prescribed during pregnancy, despite a lack of evidence from randomised trials on the benefits or risks.
Heuvelman Hein +11 more
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Serotonin reuptake inhibitors and cardiovascular disease [PDF]
, 2005 Selective serotonin re-uptake inhibiting drugs (SSRIs) are widely used for endogenous depression. In addition to depleting the nerve terminals of serotonin they also lower blood platelet serotonin levels.
Belcher, P.R. +2 more
core +1 more source
Glycogen Synthase Kinase-3 is an intermediate modulator of serotonin neurotransmission
Frontiers in Molecular Neuroscience, 2011 Serotonin is a neurotransmitter with broad functions in brain development, neuronal activity, and behaviors; and serotonin is the prominent drug target in several major neuropsychiatric diseases.
Xiaohua eLi, Abigail ePolter
doaj +1 more source
Behavioural Neurology, 2021 There are nearly 50 million Alzheimer’s disease (AD) patients worldwide, 90% of whom develop behavioral and psychological symptoms of dementia (BPSD), which increase the mortality rate of patients, and impose an economic and care burden on families and ...
Hui-Hua Li +7 more
doaj +1 more source
Signalling mechanisms of long term facilitation of breathing with intermittent hypoxia. [PDF]
, 2013 Intermittent hypoxia causes long-term facilitation (LTF) of respiratory motor nerve activity and ventilation, which manifests as a persistent increase over the normoxic baseline for an hour or more after the acute hypoxic ventilatory response.
Pamenter, Matthew E, Powell, Frank L
core +1 more source
Levo-Tetrahydroberberrubine Produces Anxiolytic-Like Effects in Mice through the 5-HT1A Receptor. [PDF]
PLoS ONE, 2017 Tetrahydroprotoberberines (THPBs) are isoquinoline alkaloids isolated from the Chinese herb Corydalis yanhusuo. In the present study, we performed competitive binding assays to examine the binding of l-THBr to neurotransmitter receptors known to be ...
Guiyun Mi +8 more
doaj +1 more source
Functional Connectivity of the Raphe Nuclei: Link to Tobacco Withdrawal in Smokers. [PDF]
, 2018 BackgroundAlthough nicotine alters serotonergic neurochemistry, clinical trials of serotonergic medications for smoking cessation have provided mixed results.
Faulkner, Paul +4 more
core +1 more source
BMC Complementary and Alternative Medicine, 2019 Background Salvia officinalis has been used successfully for the treatment of hot flushes and excessive sweating during menopause. However, modes of actions have not been elucidated conclusively.
Carsten Tober, Roland Schoop
doaj +1 more source
Strain-dependent variations in stress coping behavior are mediated by a 5-HT/GABA interaction within the prefrontal corticolimbic system [PDF]
, 2015 Background: Serotonin and γ- Aminobutyric acid (GABA) transmission is crucial in coping strategies. Methods: Here, using mice from 2 inbred strains widely exploited in behavioral neurochemistry, we investigated whether serotonin transmission in medial ...
ANDOLINA, DIEGO +3 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source