Results 11 to 20 of about 107,458 (264)

From behavioral context to receptors: serotonergic modulatory pathways in the IC

open access: yesFrontiers in Neural Circuits, 2012
In addition to ascending, descending, and lateral auditory projections, inputs extrinsic to the auditory system also influence neural processing in the inferior colliculus.
Laura M Hurley, Megan R Sullivan
doaj   +1 more source

Serotonin Receptors: Genetic insights into serotonin function [PDF]

open access: yesCurrent Biology, 1995
Targeted disruption of the genes for the 5-HT1B and 5-HT2C serotonin receptors and monoamine oxidase A have confirmed pharmacological experiments and revealed unexpected behavioral roles for serotonin.
Heath, Mark J.S., Hen, René
openaire   +2 more sources

Serotonin receptors in depression: from A to B [version 1; referees: 3 approved]

open access: yesF1000Research, 2017
The role of serotonin in major depressive disorder (MDD) is the focus of accumulating clinical and preclinical research. The results of these studies reflect the complexity of serotonin signaling through many receptors, in a large number of brain regions,
Katherine M. Nautiyal, René Hen
doaj   +1 more source

Can Serotonin 7 Receptors Be a Treatment Target for Noncentral Diseases?

open access: yesEurasian Journal of Medicine, 2023
The neurotransmitter serotonin (5-HT) is involved in several key processes in the central nervous system. But the great majority of serotonin is produced by intestinal enterochromafn cells of the gastrointestinal (GI) tract and circulating blood ...
Aslı Özbek Bilgin
doaj   +1 more source

Classification of Serotonin Receptors

open access: yesJournal of Cardiovascular Pharmacology, 1987
The subdivision of serotonin (5-HT) receptors into three classes, designated 5-HT1, 5-HT2, and 5-HT3, has been based on radioligand binding studies and experiments in isolated tissues. As a result of radioligand binding studies, two types of 5-HT recognition sites have been postulated. One site specifically labeled by [3H]5-HT was termed 5-HT1, and the
M, Göthert, E, Schlicker
openaire   +3 more sources

Serotonin-prefrontal cortical circuitry in anxiety and depression phenotypes: pivotal role of pre- and post-synaptic 5-HT1A receptor expression

open access: yesFrontiers in Behavioral Neuroscience, 2014
Decreased serotonergic activity has been implicated in anxiety and major depression, and antidepressants directly or indirectly increase the long-term activity of the serotonin system.
Paul R Albert   +4 more
doaj   +1 more source

Role of serotonin via 5-HT2B receptors in the reinforcing effects of MDMA in mice. [PDF]

open access: yesPLoS ONE, 2009
The amphetamine derivative 3,4-methylenedioxymethamphetamine (MDMA, ecstasy) reverses dopamine and serotonin transporters to produce efflux of dopamine and serotonin, respectively, in regions of the brain that have been implicated in reward. However, the
Stéphane Doly   +9 more
doaj   +1 more source

A characterization of the Manduca sexta serotonin receptors in the context of olfactory neuromodulation.

open access: yesPLoS ONE, 2013
Neuromodulation, the alteration of individual neuron response properties, has dramatic consequences for neural network function and is a phenomenon observed across all brain regions and taxa.
Andrew M Dacks   +6 more
doaj   +1 more source

Antidepressants in pregnancy: applying causal epidemiological methods to understand service-use outcomes in women and long-term neurodevelopmental outcomes in exposed children

open access: yesHealth Technology Assessment, 2023
Background Antidepressants are commonly prescribed during pregnancy, despite a lack of evidence from randomised trials on the benefits or risks.
Heuvelman Hein   +11 more
doaj   +1 more source

Glycogen Synthase Kinase-3 is an intermediate modulator of serotonin neurotransmission

open access: yesFrontiers in Molecular Neuroscience, 2011
Serotonin is a neurotransmitter with broad functions in brain development, neuronal activity, and behaviors; and serotonin is the prominent drug target in several major neuropsychiatric diseases.
Xiaohua eLi, Abigail ePolter
doaj   +1 more source

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