Results 11 to 20 of about 4,982 (186)

Low cholesterol levels are good markers for central hypothyroidism in case with dialysis using roxadustat. [PDF]

Clin Case Rep
Key Clinical Message Recently, hypoxia‐inducible factor prolyl hydroxylase (HIF‐PH) inhibitors have been used for renal anemia, but side effects have also been reported. We report on the association of central hypothyroidism and cholesterol with roxadustat.
Kita S, Okuyama H, Kondo T, Hayashi M, Nakao S, Sawamura T, Fujimoto K, Nakagawa A, Yokoyama H, Furuichi K.   +9 more
europepmc   +2 more sources

Recurrent reactive hypoglycemia due to clozapine‐induced glucose intolerance: A case report

Psychiatry and Clinical Neurosciences Reports, Volume 2, Issue 4, December 2023., 2023
Early intervention for impaired glucose tolerance may prevent clozapine discontinuation due to diabetes or hyperglycemia. Abstract Background Although diabetes is one of the most common side effects of clozapine, a medication for the treatment of schizophrenia, to the best of our knowledge no study exists on clozapine‐induced glucose intolerance or ...
Fumihiko Kawai, Satsuki Watanabe, Hirotaka Ebihara, Naoki Shimizu, Shiori Oshima, Hiroshi Okai, Yoshiko Murata, Hisatoshi Arai, Koji Matsuo   +8 more
wiley   +1 more source

Astragalus polysaccharide ameliorates insulin resistance in HepG2 cells through activating the STAT5/IGF‐1 pathway

Immunity, Inflammation and Disease, Volume 11, Issue 11, November 2023., 2023
Abstract Background Insulin resistance (IR) is considered as a major factor initiating type 2 diabetes mellitus and can lead to a reduction in glucose uptake that mainly occurs in the liver. Astragalus polysaccharide (APC), extracted from the traditional Chinese medicine, has been recorded to suppress IR.
Xinxin Yue, Wei Hao, Min Wang, Yang Fu
wiley   +1 more source

Acute abdominal pain due to atypical bilateral adrenal infarction in acute myeloid leukemia with alterations related to myelodysplasia: A case report

Clinical Case Reports, Volume 11, Issue 10, October 2023., 2023
Thoracoabdominal computed tomography with contrast enhancement on admission revealed diffusely enlarged bilateral adrenal glands with diffuse internal low‐attenuation areas. We report a case of abdominal pain and adrenal insufficiency due to AML‐induced adrenal infarction.
Risa Hirata, Masaki Tago, Shun Yamashita, Satsuki Yamamoto, Shizuka Yaita, Yuka Hirakawa, Maiko Ono, Shu‐ichi Yamashita   +7 more
wiley   +1 more source

Endocortical Trabecularization in Acromegaly: The Cause for the Paradoxically Increased Vertebral Fracture Risk?

JBMR Plus, Volume 7, Issue 10, October 2023., 2023
Normalization of disease activity was followed by an increase in BMD in lumbar spine (L1–L4) without changes in TBS, but a marked decrease in CBT in Femoral Neck and Calcar Region. These data imply endocortical trabecularization that could be linked to the high incidence of vertebral fractures following treatment of acromegaly. ABSTRACT Growth hormone (
Ansgar Heck, Kristin Godang, Tove Lekva, Kjersti Norman Markussen, Sara De Vincentis, Thor Ueland, Jens Bollerslev   +6 more
wiley   +1 more source

Stimulation of glycosaminoglycan synthesis by somatomedin and insulin in rat chondrocytes via somatomedin receptors.

Endocrinologia Japonica, 1984
Using cultured normal rat chondrocytes we have investigated 1) the effects of somatomedin and insulin on glycosaminoglycan (GAG) synthesis and 2) somatomedin and insulin binding sites. We confirmed that somatomedin and insulin stimulate GAG synthesis in normal rat chondrocytes.
Naomi Hizuka, Kazue Takano, Kazuo Shizume, Megumi Kogawa, Kumiko Asakawa   +4 more
openaire   +4 more sources

Phorbol esters stimulate the phosphorylation of receptors for insulin and somatomedin C. [PDF]

Proceedings of the National Academy of Sciences, 1983
The effect of phorbol esters on the extent of phosphorylation of receptors for insulin and somatomedin C (insulin-like growth factor I) was studied in intact IM-9 cells that were labeled by incubation with H332PO4. The tumor-promoting phorbol esters phorbol tetradecanoate acetate (TPA) and phorbol dibutyrate, but not the inactive 4 alpha-phorbol ...
Alan R. Saltiel, Naji Sahyoun, Pedro Cuatrecasas, Steven Jacobs   +3 more
openaire   +3 more sources

Expression of the insulin-like growth factor-II/mannose-6-phosphate receptor in multiple human tissues during fetal life and early infancy [PDF]

, 1992
The insulin like growth factor-II/mannose-6-phosphate (IGF-II/M6P) receptor has been detected in many cells and tissues. In the rat, there is a dramatic developmental regulation of IGF-II/M6P receptor expression, the receptor being high in fetal and ...
Eisenmenger, Wolfgang, Funk, B., Hansmann, A., Kessler, U., Kiess, W., Kolb, H. J.   +5 more
core   +1 more source

The in vitro and in vivo effects of human growth hormone administration on tumor growth of rats bearing a transplantable rat pituitary tumor (7315b) [PDF]

, 1990
The direct effects of human GH and IGF-I on PRL secretion and cell proliferation were studied on PRL secreting rat pituitary tumor 7315b cells in vitro, as well as the effects in vivo of human GH administration on body weight, IGF-I levels and tumor size
Binnerts, A. (Arjen), Hofland, L.J. (Leo), Koetsveld, P.M. (Peter) van, Lamberts, S.W.J. (Steven), Uitterlinden, P. (Piet)   +4 more
core   +1 more source

Competitive Binding of Somatomedin to the Insulin Receptors of Adipocytes, Chondrocytes, and Liver Membranes [PDF]

Proceedings of the National Academy of Sciences, 1972
The action of growth hormone on skeletal tissue is mediated through somatomedin, a low molecular weight peptide found in serum. This peptide, formerly known as “sulfation factor” or “thymidine factor,” produces marked insulin-like effects in various target tissues. Since at least some of the metabolic effects of insulin on target cells are
Louis E. Underwood, Raymond L. Hintz, David R. Clemmons, Judson J. Van Wyk   +3 more
openaire   +3 more sources