Results 11 to 20 of about 5,069 (138)

Low cholesterol levels are good markers for central hypothyroidism in case with dialysis using roxadustat. [PDF]

Clin Case Rep
Key Clinical Message Recently, hypoxia‐inducible factor prolyl hydroxylase (HIF‐PH) inhibitors have been used for renal anemia, but side effects have also been reported. We report on the association of central hypothyroidism and cholesterol with roxadustat.
Kita S, Okuyama H, Kondo T, Hayashi M, Nakao S, Sawamura T, Fujimoto K, Nakagawa A, Yokoyama H, Furuichi K.   +9 more
europepmc   +2 more sources

Estrone and estradiol concentrations in human ovaries, testes, and adrenals during the first two years of life [PDF]

, 1987
To determine the origin of estrogens in infant blood, we measured estrone (E1) and estradiol (E2) in the gonads of 50 girls and 64 boys who died suddenly between birth and 2 yr of age as well as in the adrenals of 18 of these infant girls and 16 of the ...
Bidlingmaier, F., Dorr, H. G., Eisenmenger, Wolfgang, Knorr, D., Strom, T. M.   +4 more
core   +1 more source

Differences in the Expression of Insulin‐Like Growth Factor Signaling Pathway Members in Patients With Psoriasis Vulgaris and Controls

Mediators of Inflammation, Volume 2026, Issue 1, 2026.
Insulin‐like growth factors (IGFs) and IGF–binding proteins (IGFBPs) regulate cell proliferation, differentiation, metabolic processes, and immune activities. Psoriasis is a systemic inflammatory disease with metabolic disorders as an important comorbidity in the pathogenesis of which members of the IGF family could also play a role.
Holmannova Drahomira, Borska Lenka, Fiala Zdenek, Krejsek Jan, Hamakova Kvetoslava, Cermakova Eva, Rehacek Vit, Fiala Ondrej, Maresova Tereza, Borsky Pavel, Jasbir Arora (RSS)   +10 more
wiley   +1 more source

Transfer of insulin-like growth factors I and II from plasma to lymph in young goats [PDF]

, 1992
The plasma clearance of intravenously injected '25I-labelled insulin-like growth factor I (IGFI, n = 13) and IGF-II (n = 12) and their transfer into lymph draining the foreleg of 3 5- to 8- week-old British Saanen goats was studied.
Baucells Sánchez, María Dolores, Fleet, I.R., Prosser, C.G.   +2 more
core   +2 more sources

Massive reduction of RyR1 in muscle spindles of mice carrying recessive Ryr1 mutations alters proprioception and causes scoliosis

The Journal of Physiology, Volume 603, Issue 22, Page 6949-6977, November 15, 2025.
Abstract figure legend Intrafusal muscles contained within muscle spindles are endowed with ryanodie receptor 1 (RyR1) calcium channels and participate in proprioceptor function. Mutations in RyR1 linked to severe RYR1‐congenital myopathies affect calcium release from both extrafusal as well as intrafusal muscles.
Alexis Ruiz, Sofia Benucci, Hervé Meier, Georg Schultz, Katarzyna Buczak, Christoph Handschin, Rodrigo C. G. Pena, Susan Treves, Francesco Zorzato   +8 more
wiley   +1 more source

Delayed Bone Maturation and Extended Growth Phase as Distinctive Features of 17α‐Hydroxylase/17,20‐Lyase Deficiency: A Retro‐Prospective Study of a Large Patient Cohort

Clinical Endocrinology, Volume 103, Issue 3, Page 303-310, September 2025.
ABSTRACT Introduction Worldwide, combined 17‐hydroxylase/17,20‐lyase deficiency (CYP17D) is a rare form of congenital adrenal hyperplasia, but it is the second most prevalent type in Brazil. An absence of sexual differentiation and hypergonadotropic hypogonadism arise from a reduction in the usual pattern of sex steroid formation in the adrenals and ...
Rafaela Fontenele, Flávia A. Costa‐Barbosa, Marivânia Costa‐Santos, Rafael L. Batista, Lívia M. Mermejo, Berenice B. Mendonça, Margaret de Castro, Gil Guerra‐Júnior, Claudio E. Kater, Brazilian Congenital Adrenal Hyperplasia Multicenter Study Group (BCAHMSG)   +9 more
wiley   +1 more source

A high‐resolution data set of fatty acid‐binding protein structures. III. Unexpectedly high occurrence of wrong ligands

Acta Crystallographica Section D, Volume 81, Issue 8, Page 451-464, August 2025.
Very high‐resolution fatty acid‐binding protein structures identified a substantial number of ligands that differ strongly from their expected structure. If different ligand chemistry is a potentially overlooked problem in other, lower resolution, crystal structures of protein–ligand complexes, it has repercussions for any study using such structures ...
Andreas Ehler, Christian Bartelmus, Joerg Benz, Inken Plitzko, Markus G. Rudolph   +4 more
wiley   +1 more source

2‐Octyl cyanoacrylate adjuvant use in calcaneal tendon repair: A comparative experimental study in rabbits

Journal of Experimental Orthopaedics, Volume 12, Issue 2, April 2025.
Abstract Purpose The treatment of Achilles tendon (AT) rupture can be conservative or surgical; the latter is better indicated in high‐performance athletes. The pursuit of faster recovery and reductions in skin complications and re‐ruptures have improved the tendon repair technique and early assisted rehabilitation programs.
Rogério de Andrade Gomes, Marco Antônio Percope de Andrade, Luiz Eduardo Moreira Teixeira, Bruno Jannotti Pádua, Sidney Max E. Silva, Matheus Maciel Vilela, Paulo Feliciano Sarquis Dias, Eduardo Paulino Júnior, Ivana Duval de Araújo   +8 more
wiley   +1 more source

Probiotics and Spirulina platensis Improved Growth Performance of Nile Tilapia (Oreochromis niloticus) by Upgrading Intestinal Morphology and Activating GH/IGF Axis

Aquaculture Research, Volume 2025, Issue 1, 2025.
Probiotics and spirulina are used to improve health, growth, and immunity of fish. The purpose of this study was to evaluate the effects of water additive probiotics and dietary Spirulina platensis on growth (weight gain (WG) and specific growth rate (SGR)), hematobiochemical parameters (hemoglobin (Hb) and blood glucose (Glu)), intestinal histology ...
Muallimul Islam, Haphsa Khanom, Naimul Islam, Fouzia Fariha, Bilal Ahamad Paray, Md Mahiuddin Zahangir, Md Shahjahan   +6 more
wiley   +1 more source

Insulin‐Like Growth Factors, Binding Proteins and Their Role in Pregnancy in Patients With Diabetes

Journal of Diabetes Research, Volume 2025, Issue 1, 2025.
The insulin‐like growth factor (IGF) axis, an evolutionarily conserved system, is critical in regulating cell growth, proliferation, and survival, affecting nearly all organ systems. This axis comprises two growth factors, IGF‐I and IGF‐II, and six insulin‐like growth factor–binding proteins (IGFBPs), modulating IGF activity.
Aleksandra Gladych-Macioszek, Katarzyna Ozegowska, Sandra Radzicka-Mularczyk, Rafał Sibiak, Gernot Desoye, Ewa Wender-Ozegowska, Pawel Stanirowski   +6 more
wiley   +1 more source