Results 191 to 200 of about 255,087 (307)

Placental Steroid Hormones in Preeclampsia: Multilayered Regulation of Endocrine Pathogenesis.

Endocr Rev
Yang Y, Zhang S, Fang X, Shao T, Shao X, Wang YL.   +5 more
europepmc   +1 more source

Steroid hormone receptors through Cry2 are key players in the circadian clock response to serum. [PDF]

Nat Commun
Manella G, Ezagouri S, Bolshette N, Kramer A, Golik M, Adamovich Y, Asher G.   +6 more
europepmc   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Multiplexed Tandem Mass Spectrometry Imaging Enables Large‐Scale Isomer Mapping and Annotation in Tissues

Angewandte Chemie, EarlyView.
Parallel mass spectrometry imaging acquires high mass resolution and tandem mass spectrometry images from 108 isolation windows in a single run. Spatial similarity networking clusters product ions by spatial distribution, enabling annotation of isomers and isobars as demonstrated for phospholipids and oxidized cholesterol in mouse and human brain ...
Varun V. Sharma, Gabor Toth, Robert Martinis, Cathrin E. Hansen, Gijs Kooij, Ingela Lanekoff   +5 more
wiley   +2 more sources

The Impact of Endocrine-Disrupting Chemicals on Embryonic Recurrent Implantation Failure: A Narrative Review. [PDF]

J Xenobiot
Potiris A, Antsaklis P, Christopoulos P, Kathopoulis N, Moustakli E, Anagnostaki I, Drakaki E, Arkouli N, Vogiatzoglou AL, Zikopoulos A, Stavros S, Theofanakis C.   +11 more
europepmc   +1 more source

Sex as a biological variable in nonclinical studies: Bridging scientific rigor, animal welfare, and regulatory expectations

Animal Models and Experimental Medicine, EarlyView.
Sex as a biological variable (SABV) is a critical determinant of pharmacokinetics, pharmacodynamics, and toxicity in nonclinical studies. This review highlights how inappropriate neglect of sex differences compromises animal welfare, scientific reproducibility, and regulatory compliance.
Kenta Onuma, Masaki Watanabe, Nobuya Sasaki   +2 more
wiley   +1 more source

Sexual dimorphisms in phrenic long-term facilitation following severe acute intermittent hypoxia. [PDF]

J Neurophysiol
Dougherty BJ, Grittner JML.
europepmc   +1 more source

Research progress in animal models of dry eye disease: Types, mechanisms, and application prospects

Animal Models and Experimental Medicine, EarlyView.
Pivotal multifactorial animal models for translational dry eye disease research. Abstract Dry eye disease (DED) is a prevalent and complex multifactorial ocular surface disorder, leading to significant visual discomfort and diminished quality of life.
Jinshen Liu, Jiaqi Chen, Zhonghui Li, Jiamin Zhou, Hui Zhang, Yujia Yu, Feng Cheng, Jie Bao, Chunhan Feng, Xiangqu Yu, Zhao Xia, Rao Ding, Xiang Li   +12 more
wiley   +1 more source

DHEA inhibits regeneration in <i>Lumbriculus variegatus</i>. [PDF]

MicroPubl Biol
Frank E, Pardue I, Rahman I, Banthin E, Gillen K.   +4 more
europepmc   +1 more source

Enhanced GABAergic actions resulting from the coapplication of the steroid 3α-hydroxy-5α-pregnane-11,20-dione (alfaxalone) with propofol or diazepam [PDF]

, 2018
Akk, Gustav, Cao, Lily Q, Chakrabarti, Shampuma, Evers, Alex S, Germann, Allison L, Mennerick, Steven, Montana, Michael C, Shin, Daniel J, Wozniak, David F, Yuede, Carla M   +9 more
core   +1 more source