Results 211 to 220 of about 146,907 (264)

Reconstitution of the Steroid Receptor Heterocomplex

2019
Steroid receptors are members of a subfamily of the nuclear receptor superfamily. They play a dual role of steroid hormone receptors and transcription factors. Actually, these receptors are steroid-activated transcription factors. Classical soluble receptors exist as oligomeric complexes with the Hsp90-based chaperone machinery.
Mazaira, Gisela Ileana, Galigniana, Mario Daniel   +1 more
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RECEPTORS AND STEROID‐DEPENDENT HYPERTENSION

Clinical and Experimental Pharmacology and Physiology, 1988
SUMMARY1. Repeated observations indicate that ACTH administration causes hypertension.2. Development of hypertension requires 17α‐hydroxyprogesterone and 17α, 20α‐dihydroxy‐4‐pregnene‐3‐one to be present in association with other steroids.3. The hypertensinogenic activity of corticosteroids is distinct from their glucocorticoid and mineralocorticoid ...
J P, Coghlan, A F, Reid, C D, Spence, B A, Scoggins, J A, Whitworth   +4 more
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Steroid Receptors in Pulmonary Lymphangiomyomatosis

Chest, 1984
As an initial step in investigating the role of steroid hormones in lymphangiomyomatosis, the cytosolic receptors for steroid hormones were determined by a dextran charcoal method. Specific saturable receptors were found for estrogens (measured with [3H] estradiol +/- unlabeled diethylstilbestrol), progestins (measured with [3H] R5020 +/- unlabeled ...
M M, Brentani, C R, Carvalho, P H, Saldiva, M M, Pacheco, C T, Oshima   +4 more
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Steroid Receptors in Human Meningioma

Clinical Neuropharmacology, 1984
It is well recognised that there is an increased frequency of meningioma in women compared with men and that rapid progression of the disease may occur during pregnancy. Recent studies have demonstrated steroid receptors in human meningioma. In this study we have looked for the presence of nuclear and cytoplasmic estrogen receptor (ER) and cytoplasmic ...
E, Hayward, H, Whitwell, K S, Paul, D M, Barnes   +3 more
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Steroid Hormone Receptors

1991
In the three decades since the original discovery of receptors for steroid hormones, much has been learned about the biochemical processes by which these regulatory agents exert their effects in target tissues. The intracellular receptor proteins are potential transcription factors, needed for optimal gene expression in hormone-dependent cells.
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Human kidney steroid receptors

Journal of Steroid Biochemistry, 1976
Abstract Saturation analyses, binding kinetics and agar gel electrophoresis performed on normal human kidney tissue revealed the presence of a specific progesterone receptor in all the specimens studied and in one, a specific estradiol receptor was observed, Progesterone binding had a rapid association and a slow dissociation reaction.
G, Concolino, A, Marocchi, F, Concolino, F, Sciarra, F, Di Silverio, C, Conti   +5 more
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Steroid hormones and their receptors in the brain

The Journal of Steroid Biochemistry and Molecular Biology, 1998
Steroid hormones regulate several important functions of the brain by altering the expression of particular genes through their receptors. First in this paper the localization of glucocorticoid receptor immunoreactivity and mRNA in the brain was examined. Second biphasic effects of glucocorticoid on the hippocampus was described and particular emphasis
M, Kawata, K, Yuri, H, Ozawa, M, Nishi, T, Ito, Z, Hu, H, Lu, M, Yoshida   +7 more
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Sex steroids and their receptors in lampreys

Steroids, 2008
The use of steroids and their receptors as ligand-gated transcription factors is thought to be an important step in vertebrate evolution. The lamprey is the earliest-evolving vertebrate to date in which sex steroids and their receptors have been demonstrated to have hormonal roles similar to those found in jawed vertebrates.
Mara B, Bryan, Alexander P, Scott, Weiming, Li   +2 more
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Steroid flexibility and receptor specificity

Journal of Steroid Biochemistry, 1980
Unsaturated Δ4,9 and Δ4,9,11 steroid hormones with a keto group in position 3 and a hydroxy, lactone or oxathiolane function in 17β, with or without methyl substituents in positions 17α, 18 and/or 7α, tend to compete significantly for specific binding to the receptor proteins corresponding to several steroid hormone classes (progestin, androgen ...
J, Delettré, J P, Mornon, G, Lepicard, T, Ojasoo, J P, Raynaud   +4 more
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Steroid Receptors in Breast Cancer

Archives of Internal Medicine, 1982
Since the report by Beatson1in 1896 of human mammary tumor regression occurring after bilateral oophorectomy, much interest has developed in the hormonal dependence of these tumors. Subsequently, it has been shown that a wide variety of both ablative, eg, adrenalectomy and hypophysectomy, and additive, eg, estrogen, progestin, androgen, and ...
K, Cowan, M, Lippman
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