Results 221 to 230 of about 146,907 (264)

Subnuclear trafficking of steroid receptors

Biochemical Society Transactions, 1997
Cellular responses to steroid hormones are mediated by intracellular receptor proteins whose transcriptional regulatory activity is uncovered upon ligand binding and activation. Thus, steroid hormones utilize a streamlined signal transduction system in which a single protein, the steroid receptor, functions to both recognize the hormonal signal and ...
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Cdc25B as a Steroid Receptor Coactivator

2004
The traditional role of the Cdc25 family of dual-specificity phosphatases is to activate cyclin-dependent kinases (CDKs) to enable progression through the cell cycle. This chapter reports that in addition to its cell cycle role, Cdc25B functions as a novel steroid receptor coactivator (SRC).
Ngan, E, Ma, Z, Tsai, SY, Chua, SS
openaire   +4 more sources

Steroid Receptors and Breast Cancer

Hospital Practice, 1980
Endocrine therapy can significantly prolong life in about a third of patients with advanced mammary carcinoma, but until recently it has been impossible to predict which ones. Assays for receptors specific for estrogen and progesterone have made the predictive process more accurate, and antiestrogens are providing the basis for a new approach to ...
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Steroid Receptor Coactivator Peptidomimetics

2003
Publisher Summary This chapter focuses on the methods that are useful for designing and synthesizing a series of coactivator peptidomimetics (axXXbxcx) of the L1XXL2L3 sequence to identify specific inhibitors of particular hormone receptor (NR)–coactivator interactions.
Timothy R, Geistlinger, R Kiplin, Guy
openaire   +2 more sources

Steroid Receptors

JAMA: The Journal of the American Medical Association, 1977
J A, Holt, T A, Caputo, K M, Kelly
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Non-steroidal steroid receptor modulators.

IDrugs : the investigational drugs journal, 2006
The discovery and launch of non-steroidal ligands for estrogen receptors (ERs) and for androgen receptors (ARs) demonstrated the potential of these ligands as therapeutic agents. Based on these successes, substantial attention in the past ten years has been focused on identifying non-steroidal ligands for all of the classic steroid receptors.
Pedro H H, Hermkens, Sarah, Kamp, Scott, Lusher, Gerrit H, Veeneman   +3 more
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Steroid Hormone Receptors: A Survey

1976
Publisher Summary This chapter discusses the function and mechanism of steroid hormone receptors. The interaction and retention of a steroid hormone with its target cells is not a random process but is mediated by an integrated sequence of molecular events. Secreted hormones are transported in the plasma as relatively stable complexes, resulting from
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Steroid receptor signalling

General and Comparative Endocrinology, 2007
Bury, N, Prunet, P
openaire   +4 more sources

Mycolicibacterium cell factory for the production of steroid-based drug intermediates

Biotechnology Advances, 2021
Anqi Zhao, Zhi Wang, Yongkun Lv
exaly  

Steroid hormones in the aquatic environment

Science of the Total Environment, 2021
Mark D Scrimshaw, J P Sumpter
exaly