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Reproduction under Siege: How Chronic Stress Hijacks the HPG Axis?
NeuroendocrinologyXu D, Zhao X, Chen W, Liu Y, Wang C.
europepmc +1 more source
Nuclear receptors outside the nucleus: extranuclear signalling by steroid receptors [PDF]
Nature Reviews Molecular Cell Biology, 2016 Steroid hormone receptors mediate numerous crucial biological processes and are classically thought to function as transcriptional regulators in the nucleus.
Stephen Hammes, Ellis Levin
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Non-Steroidal Steroid Receptor Modulators
Current Medicinal Chemistry, 2005The last ten years much attention has been focused on the finding of non-steroidal ligands for steroidal nuclear receptors for reasons such as diminishing cross-reactivity to eliminate side effect profiles, changing physicochemical properties which might cause different tissue distribution profiles and altering binding modes which influence the binding
Rogier C, Buijsman +4 more
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Journal of Endocrinological Investigation, 1989
Estradiol and progesterone receptor proteins (ER, PgR) have been demonstrated in neoplastic and non-neoplastic human thyroid. The aim of this study was to determine the sexual steroid receptor content of pathological non-malignant thyroid (solitary adenoma, simple nontoxic goiter), and the adjacent normal tissue of the thyroid.
M, Marugo +5 more
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Estradiol and progesterone receptor proteins (ER, PgR) have been demonstrated in neoplastic and non-neoplastic human thyroid. The aim of this study was to determine the sexual steroid receptor content of pathological non-malignant thyroid (solitary adenoma, simple nontoxic goiter), and the adjacent normal tissue of the thyroid.
M, Marugo +5 more
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The Journal of Steroid Biochemistry and Molecular Biology, 1994
The genomic mode of action is believed to represent the predominant effect of a steroid hormone. Recently, however, rapidly manifesting, non-genomic effects have also been observed. These are mediated mostly by allosteric interaction of a steroid with heterologous target structures such as membrane receptors, a prototype example being the GABAA.
S, Schwarz, P, Pohl
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The genomic mode of action is believed to represent the predominant effect of a steroid hormone. Recently, however, rapidly manifesting, non-genomic effects have also been observed. These are mediated mostly by allosteric interaction of a steroid with heterologous target structures such as membrane receptors, a prototype example being the GABAA.
S, Schwarz, P, Pohl
openaire +2 more sources
Best Practice & Research Clinical Obstetrics & Gynaecology, 2004
The ovarian hormones oestradiol and progesterone exert their actions on target cells predominantly through the binding and activation of the oestrogen receptor (ER) and progesterone receptor (PR), respectively. These receptors are members of the steroid/thyroid hormone superfamily of ligand-dependent transcription factors and bind to the control ...
Jan J, Brosens +3 more
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The ovarian hormones oestradiol and progesterone exert their actions on target cells predominantly through the binding and activation of the oestrogen receptor (ER) and progesterone receptor (PR), respectively. These receptors are members of the steroid/thyroid hormone superfamily of ligand-dependent transcription factors and bind to the control ...
Jan J, Brosens +3 more
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1976
Publisher Summary This chapter discusses different aspects of steroid hormone receptors. Steroid hormones show different kinds of activities when examined at the physiological level. Differences may be also classified in terms of gross biological responses.
E E, Baulieu +9 more
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Publisher Summary This chapter discusses different aspects of steroid hormone receptors. Steroid hormones show different kinds of activities when examined at the physiological level. Differences may be also classified in terms of gross biological responses.
E E, Baulieu +9 more
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Steroid Receptors in Osteoblasts
Clinical Orthopaedics and Related Research, 1980Using the whole-cell incubation system at 37 degrees C, the specific bindings for 3H-dexamethasone, 3H-estradiol-17 beta, 3H-dihydrotestosterone and 3H-R5020 were measured in the purified, putative osteoblasts isolated from fetal rat calvaria by collagenase digestion.
T, Yoshioka +3 more
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