Results 211 to 220 of about 78,914 (316)

A review of natural compounds to regulate platelet aggregation: molecular mechanism and research advance. [PDF]

Front Pharmacol
Hou Y, Li H, Zhu L, Li Y, Zeng Y, Quan T, Xiang Z, Zhang Y, Bian Y, Wei Y.   +9 more
europepmc   +1 more source

Experimental infection of horses with African horse sickness virus results in overt disseminated intravascular coagulation

Equine Veterinary Journal, Volume 58, Issue 2, Page 619-629, March 2026.
Abstract Background African horse sickness (AHS), caused by the vector‐borne African horse sickness virus (AHSV), is endemic to sub‐Saharan Africa and infection results in high mortality in naïve equine populations. Clinical signs include submucosal petechiae and prolonged bleeding post venepuncture indicative of hypocoagulation.
Eva Christina Schliewert, Emma H. Hooijberg, Amelia Goddard   +2 more
wiley   +1 more source

Inhibition of FXa could be a novel therapeutic target associated with hypoxia-associated tumor behavior? [PDF]

Discov Oncol
Bayrak O, Mert N, Basbinar Y, Bayrak S.
europepmc   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Effect of Platelet-Derived Microparticles on the Expression of Adhesion Molecules in Endothelial Cells. [PDF]

Int J Mol Sci
Varela-López E, Pina-Canseco S, Massó-Rojas F, Lerma C, Domínguez AMM, Ávila JOG, Torres-Narváez JC, Vargas-González A, Páez-Arenas A.   +8 more
europepmc   +1 more source

Secretory autophagy and epithelial‐to‐mesenchymal transition in cadaveric AMD samples: Novel pathways in disease progression

Acta Ophthalmologica, Volume 104, Issue 2, Page 239-251, March 2026.
Abstract Purpose To examine the presence of secretory autophagy and epithelial–mesenchymal transition (EMT) in the macular retinal pigment epithelium (RPE) of human cadaver eyes with different forms of age‐related macular degeneration (AMD). Methods Human cadaver macula samples representing dry and wet AMD, as well as age‐matched controls, were ...
Iswariyaraja Sridevi Gurubaran, Ali Koskela, Hanna Heloterä, Kai Kaarniranta   +3 more
wiley   +1 more source

Activation of the coagulation cascade as a mechanism for selective nanoparticle-mediated RNA delivery to the endothelium in vivo. [PDF]

Sci Adv
Guzman EB, Kowalski PS, Langer RS, Anderson DG.   +3 more
europepmc   +1 more source

Trends in Antithrombotic Therapy Initiation Among Patients With Stroke Pre‐ and Post–COVID‐19 in Sweden—An Interrupted Time Series Study

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
ABSTRACT Background Antithrombotic therapy constitutes a critical part of stroke management, and its utilization serves as an important indicator in the assessment of stroke care. However, knowledge on how the pandemic influenced the antithrombotic utilization after stroke remains limited.
Salar Mousa, Katarina Persson, Maria Palmetun‐Ekbäck, Fredrik Nyberg, Huiqi Li, Björn Wettermark, MohammadHossein Hajiebrahimi   +6 more
wiley   +1 more source

Transforming Coagulation Testing: The Role of Biosensors in Prothrombin Time (PT) Measurement. [PDF]

ACS Omega
Weerarathna IN, Kumar P, Kundy S, Gawande MS, Jayakody Arachchige MH, Arora S.   +5 more
europepmc   +1 more source

Semaglutide and tirzepatide effects on cardiovascular outcomes in people with overweight or obesity in the real world (STEER)

Diabetes, Obesity and Metabolism, Volume 28, Issue 3, Page 2403-2415, March 2026.
Abstract Aims To assess the real‐world effectiveness of semaglutide versus tirzepatide in reducing major adverse cardiovascular events (MACE) among patients with overweight/obesity and established atherosclerotic cardiovascular disease (ASCVD) without diabetes in an insured US population.
Lauren Wilson, Zhenxiang Zhao, Victoria Divino, Matthew Bassan, Bríain Ó. Hartaigh, Signe Stensen, Kerem Ozer   +6 more
wiley   +1 more source