Computational screening and molecular dynamics reveal curcumin III and taxifolin as potential thyroid receptor modulators for hypothyroidism therapy. [PDF]
Oyinloye BE +11 more
europepmc +1 more source
Abstract Childhood obesity is rising and leading to serious co‐morbidities, among which is metabolic dysfunction‐associated steatotic liver disease (MASLD) predisposing individuals to cirrhosis. We describe a young 11‐year‐old Hispanic male who presented with hepatopulmonary syndrome secondary to cirrhotic portal hypertension from metabolic dysfunction‐
Shruti Sakhuja +6 more
wiley +1 more source
ABSTRACT Type 2 diabetes mellitus (T2DM) is associated with an increased risk of osteoporosis and fractures, and denosumab, a non‐kidney‐excreted antiresorptive medication, represents a viable alternative to bisphosphonates for osteoporosis treatment in patients with T2DM. This study aimed to investigate the association among denosumab adherence, renal
Yu‐Chuan Chang +7 more
wiley +1 more source
Thyroid hormones and breast cancer: untangling the association. [PDF]
Fernandes I +3 more
europepmc +1 more source
ABSTRACT Rheumatoid arthritis (RA) is a common autoimmune disease, and early diagnosis is critical for effective treatment. This study aims to identify potential biomarkers related to pyroptosis through serum proteomics analysis, offering new insights for the early diagnosis of RA.
Lei Wang +10 more
wiley +1 more source
Zebrafish: a key model for unraveling endocrine-disrupting effects on thyroid development and function. [PDF]
Mezzalira N +2 more
europepmc +1 more source
Knee arthroplasty failure is associated with significant systemic multimetal exposure
Abstract Purpose This study investigated whether patients scheduled for revision total knee arthroplasty (TKA) are systemically exposed to arthroplasty metals, and whether systemic metal levels in these patients differ depending on the implants' levels of constraint.
Anna Flindt +8 more
wiley +1 more source
The assumption of a threshold is false in risk assessments for endocrine disrupting chemicals (EDCs) when endogenous hormones being disrupted are already above any possible threshold: a policy failure by the US FDA. [PDF]
Vom Saal FS, Welshons WV.
europepmc +1 more source
Mapping molluscan endocrinology: a systematic and critical appraisal. [PDF]
Panagiotidis K +3 more
europepmc +1 more source
Choice and Death: Analysis of Medical Assistance in Dying for Head and Neck Cancer in Ontario
The uptake of MAiD for head and neck cancer (HNC) has been steadily increasing since 2016, when MAiD first became available in Canada. Our study projects a substantial increase in the future use of MAiD for patients with HNC. As such, our health system needs to re‐evaluate and implement the necessary infrastructure to support the projected increase in ...
Tanika Curry +8 more
wiley +1 more source

