Results 131 to 140 of about 63,960 (263)

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

Journal of Applied Toxicology, EarlyView.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger, Melissa M. Heintz, Laurie C. Haws, Chad M. Thompson   +3 more
wiley   +1 more source

Melatonin and Indole-3-Propionic Acid Reduce Surface FcγRIII/CD16-Related Parameters in Porcine Peripheral Blood Mononuclear Cells In Vitro. [PDF]

Int J Mol Sci
Śliwka PW, Stępniak J, Karbownik-Lewińska M.   +2 more
europepmc   +1 more source

Steroidopathies and hormonal imbalance in children and adolescents with autism spectrum disorder

JCPP Advances, EarlyView.
Abstract Background Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition with a multifactorial etiology, many aspects of which remain unclear. Emerging evidence suggests a potential association between ASD and clinical manifestations resulting from hormonal imbalances, henceforth named “steroidopathies.” The present study aims to ...
Concetta de Giambattista, Patrizia Ventura, Samuele Cortese, Paolo Trerotoli, Alessandra Di Gioia, Lucia Margari   +5 more
wiley   +1 more source

Chronic Opioid Use and Endocrine Disruption in Women: Mechanisms, Life-Course Vulnerabilities, and Reproductive Health Implications. [PDF]

J Xenobiot
Alucozai D, Kwo E.
europepmc   +1 more source

Molecular theranostics: principles, challenges and controversies

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 156-164, March 2025.
Molecular theranostics offers a powerful tool to drive precision medicine in nuclear oncology. While theranostics is not a new principle in nuclear medicine, recent advances in instrumentation and radiopharmacy have driven a reinvigoration and a broader suite of applications.
Geoffrey Currie
wiley   +1 more source

Navigating thyroid hormone signaling in liver fibrosis: mechanisms and clinical implications. [PDF]

J Endocrinol Invest
Ye C, Xu K, Lan X, Quan S, Li Y, Yang W, Liu S.   +6 more
europepmc   +1 more source

Inter‐tissue relationships of gene expression in liver, muscle and adipose tissue of children with end‐stage chronic liver disease

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives End‐stage chronic liver disease in children is associated with sarcopenia and aberrant adipose tissue mass. We investigated correlations between liver pathology‐associated gene pathways (fibrosis, inflammation and steatosis) and metabolic genes in muscle and adipose tissue.
Eirini Kyrana, Cheng Zhang, Han Jin, Siamak Salehi, Jonathan C. K. Wells, Maesha Deheragoda, Ragai R. Mitry, Anil Dhawan   +7 more
wiley   +1 more source

Toxicological Effects and Health Impacts of Per- and Polyfluoroalkyl Substances (PFAS) in Humans. [PDF]

Toxics
Ma J, Gao G, Meng B, Wei X, Zhao L, Ge Z.   +5 more
europepmc   +1 more source

Understanding and Addressing Delays in Endocrine Surgery: Insights From a Mixed‐Methods Study and a Pilot Educational Intervention

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives Delays in endocrine surgical care contribute to adverse events, patient dissatisfaction, and mortality. Communication is an overlooked contributor. This study identified multi‐level drivers of delay and piloted a provider‐focused intervention. Methods We conducted an IRB‐approved mixed‐methods study.
Stella Kim, Maxwell Foote, Sophia Zhang, Audrey Twyford, Abigail Fox, Jennifer E. Rosen   +5 more
wiley   +1 more source

The unseen impact of subclinical hypothyroidism on lipid profile and cardiovascular risk. [PDF]

Biochem Biophys Rep
Mawlood MS.
europepmc   +1 more source