Results 11 to 20 of about 2,382,295 (256)

Quantum Dots Encapsulated with Canine Parvovirus-Like Particles Improving the Cellular Targeted Labeling. [PDF]

PLoS ONE, 2015
Quantum dots (QDs) have a promising prospect in live-cell imaging and sensing because of unique fluorescence features. QDs aroused significant interest in the bio-imaging field through integrating the fluorescence properties of QDs and the delivery ...
Dan Yan, Bin Wang, Shiqi Sun, Xia Feng, Ye Jin, Xueping Yao, Suizhong Cao, Huichen Guo   +7 more
doaj   +1 more source

Transferrin receptor-mediated internalization and intracellular fate of conjugates of a DNA aptamer

Molecular Therapy: Nucleic Acids, 2022
Aptamers have excellent specificity and affinity in targeting cell surface receptors, showing great potential in targeted delivery of drugs, siRNA, mRNA, and various nanomaterials with therapeutic function.
Nan Zhang, Junyan Wang, Tao Bing, Xiangjun Liu, Dihua Shangguan   +4 more
doaj   +1 more source

RELATIONSHIP OF CHANGES IN HEMATOLOGICAL AND BIOCHEMICAL INDICATORS OF PERIPHERAL BLOOD WITH THE TRANSFERRIN CONCENTRATION AND CD71+ LYMPHOCYTE COUNT

Siberian Journal of Life Sciences and Agriculture, 2022
Transferrin is an essential component of cell growth and metabolic processes that require iron. An increase in the expression of transferrin receptors on lymphocytes ensures their differentiation, maturation and activation of proliferation.
Veronika V. Patrakeeva, Liliya K. Dobrodeeva, Natal’ya P. Geshavec   +2 more
doaj   +1 more source

A method to selectively internalise submicrometer boron carbide particles into cancer cells using surface transferrin conjugation for developing a new boron neutron capture therapy agent

Journal of Experimental Nanoscience, 2020
With the goal of developing a new type of boron neutron capture therapy (BNCT) agent, selective internalisation of submicrometer boron carbide spherical particles into cancer cells via surface transferrin conjugation is demonstrated and confirmed in ...
Takuma Tsuji, Hiroshi Yoshitomi, Yoshie Ishikawa, Naoto Koshizaki, Motoshi Suzuki, Jiro Usukura   +5 more
doaj   +1 more source

Endosomal LC3C-pathway selectively targets plasma membrane cargo for autophagic degradation

Nature Communications, 2022
Autophagy can selectively target cargo for degradation. Here the authors map the proximal interactome of ATG8-paralogs LC3B and LC3C uncovering an LC3C-Endocytic-Associated-Pathway that selectively recruits internalized plasma membrane cargo, Met and ...
Paula P. Coelho, Geoffrey G. Hesketh, Annika Pedersen, Elena Kuzmin, Anne-Marie N. Fortier, Emily S. Bell, Colin D. H. Ratcliffe, Anne-Claude Gingras, Morag Park   +8 more
doaj   +1 more source

Magnetic and Fluorescent Dual-Labeled Genetically Encoded Targeted Nanoparticles for Malignant Glioma Cell Tracking and Drug Delivery

Pharmaceutics, 2023
Human glioblastoma multiforme (GBM) is a primary malignant brain tumor, a radically incurable disease characterized by rapid growth resistance to classical therapies, with a median patient survival of about 15 months.
Anna N. Gabashvili, Nelly S. Chmelyuk, Vera V. Oda, Maria K. Leonova, Viktoria A. Sarkisova, Polina A. Lazareva, Alevtina S. Semkina, Nikolai A. Belyakov, Timur R. Nizamov, Petr I. Nikitin   +9 more
doaj   +1 more source

Crossing the Iron Gate: Why and How Transferrin Receptors Mediate Viral Entry.

Annual review of nutrition, 2018
Because both the host and pathogen require iron, the innate immune response carefully orchestrates control over iron metabolism to limit its availability during times of infection. Nutritional iron deficiency can impair host immunity, while iron overload
M. Wessling-Resnick
semanticscholar   +1 more source

Insights from targeting transferrin receptors to develop vaccines for pathogens of humans and food production animals

Frontiers in Cellular and Infection Microbiology, 2023
While developing vaccines targeting surface transferrin receptor proteins in Gram-negative pathogens of humans and food production animals, the common features derived from their evolutionary origins has provided us with insights on how improvements ...
Nikolas F. Ewasechko, Somshukla Chaudhuri, Anthony B. Schryvers, Anthony B. Schryvers   +3 more
doaj   +1 more source

Targeting transferrin receptors at the blood-brain barrier improves the uptake of immunoliposomes and subsequent cargo transport into the brain parenchyma

Scientific Reports, 2017
Drug delivery to the brain is hampered by the presence of the blood-brain barrier, which excludes most molecules from freely diffusing into the brain, and tightly regulates the active transport mechanisms that ensure sufficient delivery of nutrients to ...
K. B. Johnsen, A. Burkhart, Fredrik Melander, P. Kempen, Jonas Bruun Vejlebo, P. Siupka, M. Nielsen, T. Andresen, T. Moos   +8 more
semanticscholar   +1 more source

Investigation into the Antigenic Properties and Contributions to Growth in Blood of the Meningococcal Haemoglobin Receptors, HpuAB and HmbR. [PDF]

PLoS ONE, 2015
Acquisition of iron from host complexes is mediated by four surface-located receptors of Neisseria meningitidis. The HmbR protein and heterodimeric HpuAB complex bind to haemoglobin whilst TbpBA and LbpBA bind iron-loaded transferrin and lactoferrin ...
Fadil A Bidmos, Hannah Chan, Uta Praekelt, Isfahan Tauseef, Youssif M Ali, Edward B Kaczmarski, Ian Feavers, Christopher D Bayliss   +7 more
doaj   +1 more source