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Mesoporous silica nanoparticles in glioblastoma: smart nano-platforms for targeted therapy and precision diagnosis. [PDF]
3 BiotechHiremath P +9 more
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Strategies for delivering drugs across the blood-brain barrier for the treatment of neurodegenerative diseases. [PDF]
Front Drug DelivZhang X, Fu M, Wang Y, Wu T.
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Cell surface localisation of GPI-anchored receptors in Trypanosoma brucei
Banerjee S +6 more
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Transferrin and transferrin receptors update
Free Radical Biology and Medicine, 2019In vertebrates, transferrin (Tf) safely delivers iron through circulation to cells. Tf-bound iron is incorporated through Tf receptor (TfR) 1-mediated endocytosis. TfR1 can mediate cellular uptake of both Tf and H-ferritin, an iron storage protein. New World arenaviruses, which cause hemorrhagic fever, and Plasmodium vivax use TfR1 for entry into host ...
Hiroshi Kawabata
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Annual Review of Medicine, 1993
The transferrin receptor plays a critical role in iron metabolism by precisely contrOlling the flow of transferrin iron into body cells. A soluble truncated form of the receptor can be detected in human serum using sensitive immunoassays, and the initial clinical experience with this new measurement indicates that it reflects the total body mass of ...
J D, Cook, B S, Skikne, R D, Baynes
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The transferrin receptor plays a critical role in iron metabolism by precisely contrOlling the flow of transferrin iron into body cells. A soluble truncated form of the receptor can be detected in human serum using sensitive immunoassays, and the initial clinical experience with this new measurement indicates that it reflects the total body mass of ...
J D, Cook, B S, Skikne, R D, Baynes
openaire +3 more sources
Transferrin/transferrin receptor‐mediated drug delivery
Medicinal Research Reviews, 2002AbstractSince transferrin was discovered more than half a century ago, a considerable effort has been made towards understanding tranferrin‐mediated iron uptake. However, it was not until recently with the identification and characterization of several new genes related to iron homeostasis, such as the hemochromatosis protein HFE and the iron ...
Hongyan, Li, Zhong Ming, Qian
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The International Journal of Biochemistry & Cell Biology, 2004
With the discovery that transferrin serves as the iron source for hemoglobin-synthesizing immature red blood cells came the demonstration that a cell surface receptor, now known as transferrin receptor 1, is required for iron delivery from transferrin to cells.
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With the discovery that transferrin serves as the iron source for hemoglobin-synthesizing immature red blood cells came the demonstration that a cell surface receptor, now known as transferrin receptor 1, is required for iron delivery from transferrin to cells.
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Reticulocyte membrane transferrin receptors
Canadian Journal of Biochemistry, 1980A membrane protein with specific transferrin binding activity has been isolated from rabbit reticulocytes. The isolation procedure involved the immunoprecipitation by antibody to transferrin of transferring–receptor complexes from reticulocyte membrane proteins which had been solubilized with nonionic detergent.
B, Ecarot-Charrier +3 more
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