Training in normobaric hypoxia induces hematological changes that affect iron metabolism and immunity. [PDF]
Nolte S+13 more
europepmc +1 more source
eGFR slope as predictor of mortality in heart failure patients
Abstract Aims Heart failure (HF) leads to an imbalance between heart and kidney function, resulting in poor outcomes. However, the prognostic significance of the estimated glomerular filtration rate (eGFR) trajectory in HF patients remains unclear. We analysed electronic health records (EHRs) of real‐world HF patients, assessing eGFR trajectories and ...
Sofie Verstreken+10 more
wiley +1 more source
Crossing the Blood-Brain Barrier: Innovations in Receptor- and Transporter-Mediated Transcytosis Strategies. [PDF]
Ding L+3 more
europepmc +1 more source
Abstract Aims Iron deficiency (ID) is prevalent in chronic heart failure (HF) but lacks a consensus definition. This study evaluates the prevalence and the prognostic impact of ID using different criteria on all‐cause and cardiovascular mortality, as well as first hospitalization for HF in patients with new‐onset chronic HF.
Abdullahi Ahmed Mohamed+12 more
wiley +1 more source
RNA Sequence Analysis in Macrophages Infected With Trypanosoma cruzi: Focus on TLR2 and TLR7, Iron Metabolism, and Extracellular Matrix Biosynthesis. [PDF]
Callejas-Hernández F+7 more
europepmc +1 more source
Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen+7 more
wiley +1 more source
Intracranial glioma xenograft model rapidly reestablishes blood–brain barrier integrity for longitudinal imaging of tumor progression using fluorescence molecular tomography and contrast agents [PDF]
Achilefu, Samuel+9 more
core +1 more source
Advances in brain-targeted delivery strategies and natural product-mediated enhancement of blood-brain barrier permeability. [PDF]
Liu S+9 more
europepmc +1 more source
Host Ferritin Translocates into the Chlamydial Inclusion: A Clear Alteration in its Subcellular Distribution as a Result of Infection [PDF]
Al-Younes, H., Meyer, T.
core +1 more source
Implementation of guidelines for intravenous iron therapy in heart failure patients
Abstract Aims We aim to evaluate the implementation of the 2021 ESC Guidelines regarding screening and treatment of iron deficiency in patients with heart failure (HF) at Karolinska University Hospital. Methods and results Patients with left ventricular ejection fraction (LVEF) < 50% and New York Heart Association (NYHA) class II–IV who visited ...
Milou Gamage+5 more
wiley +1 more source