Results 251 to 260 of about 2,380,315 (334)

Oral ferric maltol improves iron deficiency anaemia in patients with chronic heart failure

European Journal of Heart Failure, EarlyView.
Tibor Kempf, Welf Geller, Jan Fuge, Mircea‐Andrei Sandu, Marius M. Hoeper, Roman Pfister, Sascha Macherey‐Meyer, Stefan Störk, Daniel Scheiber, Jürgen Bogoviku, Jörn Tongers, Tarek Bekfani, Christoph Schindler, Dominik Berliner, Udo Bavendiek, Johann Bauersachs   +15 more
wiley   +1 more source

In Vitro Assessment of Drug‐Induced Liver Injury Using Three‐Dimensional Cultured HepaSH Cells Derived From Chimeric Mouse Model With Humanized Liver

Journal of Applied Toxicology, EarlyView.
ABSTRACT Drug‐induced liver injury (DILI) is a serious adverse event and a common cause of postmarketing drug withdrawal. Despite nonclinical assessments of DILI risk, which are predominantly conducted in experimental animals, DILI remains a frequent adverse event, highlighting the need to improve nonclinical assessments.
Xingming Liu, Yuichiro Higuchi, Yuta Sakamoto, Shota Yanagida, Shotaro Uehara, Hiroshi Suemizu, Yasunari Kanda, Hiroyuki Kawagishi   +7 more
wiley   +1 more source

Iron Deficiency Is Associated With Impaired Myocardial Reperfusion in ST-Segment-Elevation Myocardial Infarction: Influence of the Definition Used. [PDF]

J Am Heart Assoc
Barrabés JA, Inserte J, Castellote L, Buera I, Milà L, Sambola A, Uribarri A, Vidal M, Aluja D, Delgado-Tomás S, Tobías-Castillo PE, Calvo-Barceló M, Guala A, Rodríguez-Palomares JF, Del Blanco BG, Beneítez D, Ferreira-González I.   +16 more
europepmc   +1 more source

Management of paediatric ulcerative colitis, part 1: Ambulatory care—An updated evidence‐based consensus guideline from the European Society of Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organisation

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Despite advances in the management of ambulatory paediatric ulcerative colitis (UC), challenges remain as many patients are refractory to therapy and some require colectomy. The aim of these guidelines is to provide an update on optimal care for UC through detailed recommendations and practice points. Methods These guidelines are an
Eytan Wine, Marina Aloi, Stephanie Van Biervliet, Jiri Bronsky, Javier Martín di Carpi, Marco Gasparetto, Laura Gianolio, Hannah Gordon, Iva Hojsak, Alexandra S. Hudson, Séamus Hussey, Johan van Limbergen, Erasmo Miele, Lorenzo Norsa, Ola Olén, Gianluca Pellino, Patrick van Rheenen, Lissy de Ridder, Richard K. Russell, Dror S. Shouval, Eunice Trindade, Dan Turner, David C. Wilson, Anat Yerushalmy Feler, Amit Assa   +24 more
wiley   +1 more source

Paediatric acute liver failure: A prospective, nationwide, population‐based surveillance study in Germany

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Paediatric acute liver failure (PALF) is a rare but life‐threatening condition, yet comprehensive epidemiological data in Germany are lacking. Our study aimed to systematically analyse incidence, aetiology, and outcome of PALF in Germany.
Dominic Lenz, Muhammad Abdulaziz, Bianca Peters, Matias Wagner, Lea D. Schlieben, Victor M. Corman, Ulrich Baumann, Philip Bufler, Tal Dattner, Rainer Ganschow, Kristin Genzel, Nicole Hammann, Steffen Hartleif, Bianca Hegen, Stephan Henning, André Hoerning, Martin Jankofsky, Norman Junge, Simone Kathemann, Birgit Knoppke, Martina Kohl‐Sobania, Martin Laass, Elke Lainka, Eberhard Lurz, Michael Melter, Hanna Müller, Denisa Pilic, Markus Ries, Lisa Schiefele, Tobias Schwerd, Ekkehard Sturm, Mechtild Wegner, Michael S. Urschitz, Sven F. Garbade, Daniel Wenning, Christian Drosten, Alexander Fichtner, Stefan Kölker, Georg F. Hoffmann, Holger Prokisch, Christian Staufner   +40 more
wiley   +1 more source

Polyphenols in the Central Nervous System: Cellular Effects and Liposomal Delivery Approaches. [PDF]

Int J Mol Sci
Kaluza M, Ksiazek-Winiarek D, Szpakowski P, Czpakowska J, Fijalkowska J, Glabinski A.   +5 more
europepmc   +1 more source

Monotropein Induced Ferroptosis to Alleviate the Progression of Hepatocellular Carcinoma via Regulating Nrf2/HO‐1/GPX4 Axis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Hepatocellular carcinoma (HCC) exhibits a high global morbidity rate and ranks as the fourth leading cause of cancer‐related mortality worldwide. In response to the urgent need for effective HCC treatments, naturally occurring, botanical‐driven compounds have gained increasing attention.
Bing Shi, Yan‐Ping Li, Zhuo Gan, Pan Chen   +3 more
wiley   +1 more source

The blood-brain barrier: a help and a hindrance. [PDF]

Brain
Rust R, Yin H, Achón Buil B, Sagare AP, Kisler K.   +4 more
europepmc   +1 more source

Toll Like Receptors in the Larynx: Implications for Laryngeal Immunology

The Laryngoscope, EarlyView.
TLR were identified in the murine and human vocal fold epithelium with slight differences in localization from true to false vocal folds in humans. In immortalized human vocal, fold epithelial cell cultures, no significant differences in relative gene expression at 24 h were observed – for TLRs 1‐9 and IL8 – with and without LPS stimulation.
Madhu Gowda, Anumitha Venkatraman, Alexandra Mechler‐Hickson, Vlasta Lungova, Susan L. Thibeault   +4 more
wiley   +1 more source

Sex Hormones and Iron-Related Biomarkers Associate with EMT Features and Tumor Stage in Colorectal Cancer: A Serum- and Tissue-Based Analysis. [PDF]

Int J Mol Sci
Squitti R, De Luca A, Severino A, Rizzo G, Marzi F, Amodio LE, Vicano G, Focaccio A, Tondolo V, Rongioletti M.   +9 more
europepmc   +1 more source