Results 21 to 30 of about 2,382,295 (256)

Influence of the genetic makeup of common carp on the expression of iron-related genes during Trypanoplasma borreli infection

open access: yesJournal of Veterinary Research, 2018
Genes related to iron metabolism play an important role in inflammatory response. The objective of this study was to investigate the role of ferritin, transferrin receptors 1a and 1b, and transferrin genes in the response to blood parasite infection in ...
Kamińska-Gibas Teresa   +3 more
doaj   +1 more source

Factors associated with iron deficiency in heart failure

open access: yesКардиоваскулярная терапия и профилактика, 2023
Aim. To establish the factors associated with iron deficiency (ID) in pa- tients with heart failure (HF).Material and methods. We examined 294 patients with NYHA class II-IV HF as follows: 213 — with ID, 81 — without ID. All patients underwent a clinical
M. P. Smirnova, P. A. Chizhov
doaj   +1 more source

Regulation of cell surface transferrin receptor-2 by iron-dependent cleavage and release of a soluble form

open access: yesHaematologica, 2015
Transferrin receptor-2 is a transmembrane protein whose expression is restricted to hepatocytes and erythroid cells. Transferrin receptor-2 has a regulatory function in iron homeostasis, since its inactivation causes systemic iron overload.
Alessia Pagani   +9 more
doaj   +1 more source

Macrophage colony-stimulating factor differentially regulates low density lipoprotein and transferrin receptors

open access: yesJournal of Lipid Research, 2004
Endocytosis mediated by both LDL receptors (LDLRs) and transferrin receptors (TfRs) occurs in clathrin-coated pits and requires specific tyrosine-based internalization sequences located in the cytoplasmic domain of these receptors.
Liqin Du, Steven R. Post
doaj   +1 more source

Identification of Transferrin Receptor 1 (TfR1) Overexpressed in Lung Cancer Cells, and Internalization of Magnetic Au-CoFe2O4 Core-Shell Nanoparticles Functionalized with Its Ligand in a Cellular Model of Small Cell Lung Cancer (SCLC)

open access: yesPharmaceutics, 2022
Lung cancer is, currently, one of the main malignancies causing deaths worldwide. To date, early prognostic and diagnostic markers for small cell lung cancer (SCLC) have not been systematically and clearly identified, so most patients receive standard ...
Rocío Villalobos-Manzo   +5 more
doaj   +1 more source

Some aspects of the transport system of iron metabolism depending on the degree of iron overload syndrome in children with chronic hepatitis B

open access: yesДетские инфекции (Москва), 2019
Objective: to study the status of markers of the transport system of iron metabolism and the marker profile of HBV infection, depending on the degree of iron overload syndrome in children with chronic hepatitis B.The object of the study were 1 85 ...
F. I. Inoyatova   +6 more
doaj   +1 more source

Local clustering of transferrin receptors promotes clathrin-coated pit initiation

open access: yesJournal of Cell Biology, 2010
The relationship between cargo accumulation and clathrin-coated pit initiation and maturation is examined by direct visualization of receptor-engaged clathrin-coated pits.
Allen P. Liu   +3 more
semanticscholar   +1 more source

Cell-Based, High-Content Screen for Receptor Internalization, Recycling and Intracellular Trafficking

open access: yesBioTechniques, 2000
A variety of physiologically important receptors are internalized and then recycled back to the plasma membrane by the endocytic recycling compartment. These include the transferrin receptor and many G-protein coupled receptors (GPCRs).
R.N. Ghosh   +6 more
doaj   +1 more source

Serum transferrin receptors are decreased in the presence of iron overload.

open access: yesClinical Chemistry, 1998
To test the hypothesis that the quantities of circulating transferrin receptors are reduced in iron overload, we studied serum transferrin receptors and indirect measures of iron status in 150 subjects from rural Zimbabwe.
H. Khumalo   +6 more
semanticscholar   +1 more source

Two Interconvertible Folds Modulate the Activity of a DNA Aptamer Against Transferrin Receptor

open access: yesMolecular Therapy: Nucleic Acids, 2014
Thanks to their ability to recognize biomolecular targets with high affinity and specificity, nucleic acid aptamers are increasingly investigated as diagnostic and therapeutic tools, particularly when their targets are cell-surface receptors.
David Porciani   +5 more
doaj   +1 more source

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