Results 11 to 20 of about 51,677 (239)
THE ROLE OF SERUM TRANSFERRIN RECEPTORS MEASUREMENT
Zdravniški Vestnik, 2004 Background. The transferrin receptors are transmembrane proteins. They have a critical role in iron metabolism by controlling the flow of transferrin iron into body cells.
Bernarda Vogrin +4 more
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Heterotypic interactions between transferrin receptor and transferrin receptor 2 [PDF]
Blood, 2003 Cellular iron uptake in most tissues occurs via endocytosis of diferric transferrin (Tf) bound to the transferrin receptor (TfR). Recently, a second transferrin receptor, transferrin receptor 2 (TfR2), has been identified and shown to play a critical role in iron metabolism.
Vogt, Todd M +4 more
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Structure of the Human Transferrin Receptor-Transferrin Complex [PDF]
Cell, 2004 Iron, insoluble as free Fe(3+) and toxic as free Fe(2+), is distributed through the body as Fe(3+) bound to transferrin (Tf) for delivery to cells by endocytosis of its complex with transferrin receptor (TfR). Although much is understood of the transferrin endocytotic cycle, little has been uncovered of the molecular details underlying the formation of
Cheng, Yifan +4 more
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Endosomal LC3C-pathway selectively targets plasma membrane cargo for autophagic degradation
Nature Communications, 2022 Autophagy can selectively target cargo for degradation. Here the authors map the proximal interactome of ATG8-paralogs LC3B and LC3C uncovering an LC3C-Endocytic-Associated-Pathway that selectively recruits internalized plasma membrane cargo, Met and ...
Paula P. Coelho +8 more
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Localization of Transferrin and Transferrin Receptors in Rat Testes [PDF]
Biology of Reproduction, 1984 One of the major proteins secreted by rat Sertoli cells in culture is a transferrin-like protein (Skinner and Griswold, 1980). The purpose of this study was to quantitate the amount of testicular transferrin in fluids isolated from the testis by the use of a radioimmunoassay and to determine the location of transferrin and transferrin receptors in the ...
S R, Sylvester, M D, Griswold
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DISTRIBUTION OF TRANSFERRIN AND TRANSFERRIN RECEPTORS IN THE RABBIT PLACENTA [PDF]
Quarterly Journal of Experimental Physiology, 1983 The quantity and distribution of transferrin and transferrin‐binding sites in the placenta were investigated in rabbits on the 28th‐29th days of pregnancy. The animals were injected intravenously with a mixture of 59Fe‐125I‐labelled rabbit diferric transferrin and 131I‐labelled rabbit albumin.
E, Baker +2 more
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Gene transfer to respiratory epithelial cells via the receptor-mediated endocytosis pathway [PDF]
, 1992 Gene-based therapies for a variety of inherited and acquired pulmonary diseases will require the development of vectors capable of safe and efficient transfer of DNA to the respiratory epithelium.
Boucher, R. C. +14 more
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Pharmaceutics, 2023 Human glioblastoma multiforme (GBM) is a primary malignant brain tumor, a radically incurable disease characterized by rapid growth resistance to classical therapies, with a median patient survival of about 15 months.
Anna N. Gabashvili +9 more
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Human amniotic fluid glycoproteins expressing sialyl Lewis carbohydrate antigens stimulate progesterone production in human trophoblasts in vitro [PDF]
, 2004 Background: Progesterone is thought to mediate immune modulator effects by regulating uterine responsiveness. The aim of the study was to clarify the effect of transferrin and glycodelin A (former name PP14) as sialyl Lewis X-expressing glycoproteins on ...
Streu, Annett +13 more
core +1 more source
Frontiers in Cellular and Infection Microbiology, 2023 While developing vaccines targeting surface transferrin receptor proteins in Gram-negative pathogens of humans and food production animals, the common features derived from their evolutionary origins has provided us with insights on how improvements ...
Nikolas F. Ewasechko +3 more
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