Results 11 to 20 of about 52,419 (262)

Cell surface localisation of GPI-anchored receptors in <i>Trypanosoma brucei</i>. [PDF]

Elife
Trypanosoma brucei, the causal agent of Human and Animal African trypanosomiasis proliferates in the extracellular milieu of mammals. It acquires host macromolecular nutrients by receptor-mediated endocytosis. The best characterised cell surface receptor
Banerjee S, Minshall N, Cook AD, Macleod O, Webb H, Higgins MK, Carrington M.   +6 more
europepmc   +2 more sources

Transferrin receptors

Experimental and Molecular Medicine
The transferrin receptor (TfR) is one of the key proteins involved in cellular iron uptake. TfR-mediated endocytosis of transferrin-bound iron is the major pathway for iron acquisition by most cells in the body.
Qian Guo, Christopher Qian, Xinyu Wang, Zhong-Ming Qian   +3 more
doaj   +3 more sources

Investigation of Trends in the Research on Transferrin Receptor-Mediated Drug Delivery via a Bibliometric and Thematic Analysis

Pharmaceutics, 2022
This study systematically reviews and characterizes the existing literature on transferrin/transferrin receptor-mediated drug delivery. Transferrin is an iron-binding protein. It can be used as a ligand to deliver various proteins, genes, ions, and drugs
Tarnjot Kaur, Jyoti Upadhyay, Sudeep Pukale, Ashish Mathur, Mohd Nazam Ansari   +4 more
doaj   +1 more source

Transferrin Receptors in Erythropoiesis [PDF]

International Journal of Molecular Sciences, 2020
Erythropoiesis is a highly dynamic process giving rise to red blood cells from hematopoietic stem cells present in the bone marrow. Red blood cells transport oxygen to tissues thanks to the hemoglobin comprised of α- and β-globin chains and of iron-containing hemes.
Richard, Cyrielle, Verdier, Frédérique
openaire   +2 more sources

Specific parameters of iron metabolism in tuberculosis

Туберкулез и болезни лёгких, 2021
The review presents data from 55 publications about specific parameters of iron metabolism in the human body including those ill with tuberculosis. It describes processes aimed at isolating iron from pathogens and promoting the acquisition of iron by ...
R. Yu. Аbdullаev, O. G. Komissаrovа, O. R. Terentievа   +2 more
doaj   +1 more source

Subcellular trafficking and transcytosis efficacy of different receptor types for therapeutic antibody delivery at the blood‒brain barrier

Fluids and Barriers of the CNS, 2023
Here, we report an experimental setup to benchmark different receptors for targeted therapeutic antibody delivery at the blood–brain barrier. We used brain capillary endothelial-like cells derived from induced pluripotent stem cells (hiPSC-BECs) as a ...
Mikkel Roland Holst, Nienke Marije de Wit, Burak Ozgür, Andreas Brachner, Kathrine Hyldig, Antje Appelt-Menzel, Hannah Sleven, Zameel Cader, Helga Eveline de Vries, Winfried Neuhaus, Allan Jensen, Birger Brodin, Morten Schallburg Nielsen   +12 more
doaj   +1 more source

Quantum Dots Encapsulated with Canine Parvovirus-Like Particles Improving the Cellular Targeted Labeling. [PDF]

PLoS ONE, 2015
Quantum dots (QDs) have a promising prospect in live-cell imaging and sensing because of unique fluorescence features. QDs aroused significant interest in the bio-imaging field through integrating the fluorescence properties of QDs and the delivery ...
Dan Yan, Bin Wang, Shiqi Sun, Xia Feng, Ye Jin, Xueping Yao, Suizhong Cao, Huichen Guo   +7 more
doaj   +1 more source

Transferrin receptor-mediated internalization and intracellular fate of conjugates of a DNA aptamer

Molecular Therapy: Nucleic Acids, 2022
Aptamers have excellent specificity and affinity in targeting cell surface receptors, showing great potential in targeted delivery of drugs, siRNA, mRNA, and various nanomaterials with therapeutic function.
Nan Zhang, Junyan Wang, Tao Bing, Xiangjun Liu, Dihua Shangguan   +4 more
doaj   +1 more source

A method to selectively internalise submicrometer boron carbide particles into cancer cells using surface transferrin conjugation for developing a new boron neutron capture therapy agent

Journal of Experimental Nanoscience, 2020
With the goal of developing a new type of boron neutron capture therapy (BNCT) agent, selective internalisation of submicrometer boron carbide spherical particles into cancer cells via surface transferrin conjugation is demonstrated and confirmed in ...
Takuma Tsuji, Hiroshi Yoshitomi, Yoshie Ishikawa, Naoto Koshizaki, Motoshi Suzuki, Jiro Usukura   +5 more
doaj   +1 more source

RELATIONSHIP OF CHANGES IN HEMATOLOGICAL AND BIOCHEMICAL INDICATORS OF PERIPHERAL BLOOD WITH THE TRANSFERRIN CONCENTRATION AND CD71+ LYMPHOCYTE COUNT

Siberian Journal of Life Sciences and Agriculture, 2022
Transferrin is an essential component of cell growth and metabolic processes that require iron. An increase in the expression of transferrin receptors on lymphocytes ensures their differentiation, maturation and activation of proliferation.
Veronika V. Patrakeeva, Liliya K. Dobrodeeva, Natal’ya P. Geshavec   +2 more
doaj   +1 more source