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Cancer research, 1995
Here we describe human colon carcinoma cell clones, isolated from a transforming growth factor beta (TGF-beta)-responsive parental cell line, which display differential sensitivities to TGF-beta 1 and TGF-beta 2 isoforms. In a monolayer proliferation assay, some clones were sensitive to both isoforms (IC50 = 0.1-0.6 ng/ml; S1S2) while others were ...
G H, Zhou +4 more
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Here we describe human colon carcinoma cell clones, isolated from a transforming growth factor beta (TGF-beta)-responsive parental cell line, which display differential sensitivities to TGF-beta 1 and TGF-beta 2 isoforms. In a monolayer proliferation assay, some clones were sensitive to both isoforms (IC50 = 0.1-0.6 ng/ml; S1S2) while others were ...
G H, Zhou +4 more
openaire +1 more source
An emerging complexity of receptors for transforming growth factor-beta.
Princess Takamatsu symposia, 1997Transforming growth factor-beta (TGF-beta) is a multifunctional protein that modulates cell proliferation and interaction with the extracellular matrix. Three common TGF-beta receptors are found on the cell surface. The type III receptor is a transmembrane proteoglycan with a short cytoplasmic domain and is thought not to be involved in TGF-beta ...
R, Derynck +4 more
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Signaling by the transforming growth factor-β receptor
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1995J M, Yingling, X F, Wang, C H, Bassing
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Receptors for transforming growth factor-beta.
Advances in immunology, 1994K, Miyazono +3 more
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The Transforming Growth Factor-beta Family
Annual Review of Cell Biology, 1990Joan Massagué Solé
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