Results 171 to 180 of about 738,282 (345)

The two different receptors for tumor necrosis factor mediate distinct cellular responses.

Proceedings of the National Academy of Sciences of the United States of America, 1991
L. Tartaglia, Richard F. Weber, Irene S. FIGARIt, Carmen REYNOLDSt, M. Palladino, D. Goeddel   +5 more
semanticscholar   +1 more source

Tumor Necrosis Factor Receptor Binding [PDF]

, 2020
openaire   +1 more source

Enhancing Magnetic Hyperthermia at the Cell Membrane by Anchoring 92R‐Functionalized Magnetic Nanoparticles to Low‐Endocytic CCR9 Surface Receptors

Advanced Healthcare Materials, EarlyView.
We present a strategy to enhance magnetic hyperthermia therapy by modulating nanoparticle–cell interactions. Antibody‐functionalized magnetic nanoparticles targeting the low‐internalizing CCR9 receptor enable spatially controlled membrane anchoring, reducing aggregation and maximizing heat generation under alternating magnetic fields.
David Egea‐Benavente, Isabel Corraliza‐Gorjón, Thomas S. van Zanten, María del Puerto Morales, Leonor Kremer, Domingo F. Barber   +5 more
wiley   +1 more source

Pharmacotherapy for rheumatoid arthritis in the early 21st century: Russian and international experience

Терапевтический архив, 2013
The paper summarizes the data of international and Russian studies concerning current approaches to the pharmacotherapy of rheumatoid arthritis. Particular emphasis is placed on the substantiation of the treat-to-target concept, on the efficacy and ...
E L Nasonov, D E Karateev, G V Lukina
doaj  

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen, Jiali Lin, Jiapeng Li, Yiwei Hu, Jiansen Su, Yu Miao, Lanlan Wang, Qian Tang, Changqing Zhang, Junhui Yin   +9 more
wiley   +1 more source

Associations between functional autoantibodies targeting GPCRs, antinuclear antibodies, and inflammatory cytokines TNF-α: a cross-sectional study of 19,810 individuals. [PDF]

Front Immunol
Chen X, Kieselbach B, Krämer BK, von Baehr V, Reichetzeder C, Hocher B.   +5 more
europepmc   +1 more source

Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor alpha in vitro and in vivo.

Proceedings of the National Academy of Sciences of the United States of America, 1992
K. Zee, T. Kohno, E. Fischer, C. S. Rock, L. Moldawer, S. Lowry   +5 more
semanticscholar   +1 more source

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

Advanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues, Maria Catarina Carreira, Mafalda S. Santos, Daniela Pacheco, Frederico Castelo Ferreira, Paola Sanjuan‐Alberte, João Carlos Silva   +6 more
wiley   +1 more source

The purinergic signaling interfaces in breast cancer angiogenesis. [PDF]

Purinergic Signal
da Silva FC, Stabile J, Fürstenau CR, Araújo TG.   +3 more
europepmc   +1 more source

Tumor Necrosis Factor Receptors: Biology and Therapeutic Potential in Kidney Diseases

American Journal of Nephrology, 2012
M. Speeckaert, R. Speeckaert, M. Laute, R. Vanholder, J. Delanghe   +4 more
semanticscholar   +1 more source