Results 201 to 210 of about 256,662 (267)

CD4⁺ T cells in cancer: dual roles, exhaustion, and therapeutic breakthroughs. [PDF]

Cancer Biol Med
Zhang Y, Xu J, Pan S, Wang Y, Zhao Q, Huang Z, Hu C, Cheng X.   +7 more
europepmc   +1 more source

Compact Tabletop Magnetic Resonance Elastography for Mapping Soft Tissue Viscoelasticity

Advanced Science, EarlyView.
This work introduces a compact, low‐cost tabletop magnetic resonance elastography platform for high‐resolution viscoelastic mapping in soft‐tissue specimens. Using this method in human colorectal liver metastases, we demonstrate fully automated biomechanical profiling of treatment response and show that heterogeneity‐based metrics outperform ...
Weijie Zhao, Lisa‐Marie Skrip, Heiko Tzschätzsch, Tom Meyer, Hossein S. Aghamiry, Alexander Arnold, Lene Änne Böhne, Jakob Jordan, Oliver Boehm, Agnes K. Boehm, Steffen Görner, Jakob Schattenfroh, Yanglei Wu, Pedro Augusto Dantas de Moraes, Johann Pratschke, Jürgen Braun, Igor M. Sauer, Jing Guo, Ingolf Sack, Karl H. Hillebrandt   +19 more
wiley   +1 more source

The microbiome-inflammation-immune axis in oral squamous cell carcinoma: from mechanistic insights to therapeutic perspectives. [PDF]

Front Immunol
Wang Z, Bian Q, Chu Y, Zhu W, Qin Y, Zheng J.   +5 more
europepmc   +1 more source

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

Adaptor proteins regulating tumor-associated macrophage polarization during cancer progression. [PDF]

Oncoscience
Wadhonkar K, Ohishi T, Baig MS.
europepmc   +1 more source

Bandgap‐Engineered PtxTey:Ag2Te Composite Quantum Dots Enable Programmable NIR‐II Imaging and Photothermal‐Immune Synergistic Therapy

Advanced Science, EarlyView.
A bandgap‐engineered PtxTey:Ag2Te quantum dot platform enables tunable NIR‐IIb emission for deep‐tissue imaging and mild photothermal therapy. Conjugation with αPD‐L1 confers dual tumor targeting and real‐time monitoring of PD‐L1 dynamics. Mild photothermal modulation induces immune reprogramming, enhancing checkpoint blockade efficacy and achieving ...
Jing Liu, Rui Xu, Quan Wu, Tian‐Xin Xiao, Lai‐Xi Zhao, Lei Sun, Ya‐Wen Zheng, Liang Dong, Zhi‐Quan Tian, Haibo Wang   +9 more
wiley   +1 more source

The Role of TNF-α in Ischemic Stroke. [PDF]

Int J Mol Sci
Kołodziejska R, Pawluk H, Tafelska-Kaczmarek A, Pawluk M, Koper K, Godlewski A, Kuk J, Sergot K, Kurhaluk N, Woźniak A.   +9 more
europepmc   +1 more source

TNFR2 is expressed by a discrete subset of epidermal T cells with an IL-17 gene signature during psoriasis. [PDF]

PLoS One
Ahmed J, Matthews C, Tulloch P, Lawler W, Mendoza A, Rhoiney M, Jameson JM.   +6 more
europepmc   +1 more source

Biomarkers for Early Detection of Diabetic Kidney Disease in Pediatric and Adolescent Populations: A Narrative Review. [PDF]

Health Sci Rep
Malekzadeh I, Falsafi N, Nazemi M, Taherkhani H, Bahroudi M, Abbas A, Moghtaderi M.   +6 more
europepmc   +1 more source