Effects of diabetes on myocardial capillary density and serum angiogenesis biomarkers in male rats [PDF]
Clinics, 2011 INTRODUCTION: Cardiovascular disease is one of the main causes of mortality and morbidity in diabetic patients. This study evaluated the effects of diabetes on myocardial capillary density and several serum angiogenic factors including nitric oxide ...
Majid Khazaei +5 more
doaj +6 more sources
Signal transduction by vascular endothelial growth factor receptors. [PDF]
Cold Spring Harbor Perspectives in Medicine, 2012 Vascular endothelial growth factors (VEGFs) are master regulators of vascular development and of blood and lymphatic vessel function during health and disease in the adult. It is therefore important to understand the mechanism of action of this family of
S. Koch, L. Claesson-Welsh
semanticscholar +4 more sources
Expression of Hypoxia-inducible factor 1-α and Vascular endothelial growth factor-C in locally advanced breast cancer patients [PDF]
Clinics, 2011 BACKGROUND: Locally advanced breast cancers are more prevalent in underdeveloped countries. Targeted therapy has been improved to identify hallmarks that are specific to these subtypes of tumors.
Luiz Gustavo Oliveira Brito +5 more
doaj +7 more sources
Vascular endothelial growth factor can signal through platelet-derived growth factor receptors [PDF]
Journal of Cell Biology, 2007 Vascular endothelial growth factor (VEGF-A) is a crucial stimulator of vascular cell migration and proliferation. Using bone marrow–derived human adult mesenchymal stem cells (MSCs) that did not express VEGF receptors, we provide evidence that VEGF-A can
Ball, Stephen G. +2 more
core +3 more sources
Influence of hypoxia and neoangiogenesis on the growth of pancreatic cancer [PDF]
Molecular Cancer, 2003 As with other solid tumors, the growth and metastasis of pancreatic cancer is critically dependent on tumor angiogenesis. A major stimulus for a tumor's recruitment of additional blood vessels is cellular hypoxia, a condition which is especially ...
Reber Howard A +3 more
doaj +5 more sources
Signal transduction by vascular endothelial growth factor receptors.
Biochemical Society Transactions, 2001 Vascular endothelial growth factor (VEGF)/vascular permeability factor is the prototype for a growing family of dimeric growth factors, which exert their effects on vascular and lymphatic endothelial cells, as well as on a wide range of other cell types.
L. Claesson-Welsh
semanticscholar +4 more sources
Anti-angiogenic and antioxidant effects of axitinib in human retinal endothelial cells: implications in diabetic retinopathy [PDF]
Frontiers in PharmacologyDiabetic retinopathy is a secondary microvascular complication of diabetes mellitus. This disease progresses from two stages, non-proliferative and proliferative diabetic retinopathy, the latter characterized by retinal abnormal angiogenesis ...
Francesca Lazzara +10 more
doaj +3 more sources
Breast Angiosarcoma: Case Series and Expression of Vascular Endothelial Growth Factor [PDF]
Case Reports in Oncology, 2009 Purpose: Angiosarcoma of the breast is a rare, malignant tumor for which little is known regarding prognostic indicators and optimal therapeutic regimens.
Rondeep Brar +5 more
doaj +4 more sources
Vasoregulatory Autoantibodies and Clinical Outcome After Ischemic Stroke—PROSCIS‐B
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023 Background Vasoregulatory autoantibodies including autoantibodies targeting G‐protein–coupled receptors might play a functional role in vascular diseases.
Thomas G. Liman +10 more
doaj +1 more source
Neural Regeneration Research, 2021 Melatonin can attenuate cardiac microvascular ischemia/reperfusion injury, but it remains unclear whether melatonin can also ameliorate cerebral microvascular abnormalities.
Pan Wang +5 more
doaj +1 more source