Results 1 to 10 of about 483,837 (349)
Signal transduction by vascular endothelial growth factor receptors. [PDF]
Cold Spring Harbor Perspectives in Medicine, 2012 Vascular endothelial growth factors (VEGFs) are master regulators of vascular development and of blood and lymphatic vessel function during health and disease in the adult. It is therefore important to understand the mechanism of action of this family of five mammalian ligands, which act through three receptor tyrosine kinases (RTKs).
S. Koch, L. Claesson-Welsh
semanticscholar +4 more sources
Signal transduction by vascular endothelial growth factor receptors.
Biochemical Society Transactions, 2001 Vascular endothelial growth factor (VEGF)/vascular permeability factor is the prototype for a growing family of dimeric growth factors, which exert their effects on vascular and lymphatic endothelial cells, as well as on a wide range of other cell types.
L. Claesson-Welsh
semanticscholar +4 more sources
Vasoregulatory Autoantibodies and Clinical Outcome After Ischemic Stroke—PROSCIS‐B
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023 Background Vasoregulatory autoantibodies including autoantibodies targeting G‐protein–coupled receptors might play a functional role in vascular diseases.
Thomas G. Liman +10 more
doaj +1 more source
Neural Regeneration Research, 2021 Melatonin can attenuate cardiac microvascular ischemia/reperfusion injury, but it remains unclear whether melatonin can also ameliorate cerebral microvascular abnormalities.
Pan Wang +5 more
doaj +1 more source
Medicina, 2023 Background and Objectives: Impaired wound healing represents an unsolved medical issue with a high impact on patients’ quality of life and global health care.
Benedikt Fuchs +5 more
doaj +1 more source
Heliyon, 2023 Background: Vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs) play complicated oncogenic roles in multiple tumors by initiating and promoting tumor angiogenesis and lymphangiogenesis.
Jianxin Li, Ting Han
doaj +1 more source
Progress of study on inflammatory factors regulating function of vascular endothelial cells from type 1 diabetes mellitus [PDF]
Jichu yixue yu linchuang, 2021 Inflammatory factors are widely involved not only in the physiopathological process of type 1 diabetes mellitus (T1DM), but also in the regulation of vascular endothelial dysfunction. A variety of inflammatory factors affect the insulin signaling pathway
LI Qian, LIU Chun-hua, WANG Chen-yi, TAN Jiao-jiao, MA Yu-ping, LYU Hai-hong
doaj
Modeling the Cluster Size Distribution of Vascular Endothelial Growth Factor (VEGF) Receptors
Bioinformatics and Biology Insights, 2022 We previously developed a method of defining receptor clusters in the membrane based on mutual distance and applied it to a set of transmission microscopy images of vascular endothelial growth factor receptors. An optimal length parameter was identified,
Emine Güven +3 more
doaj +1 more source
Progress in Research on the Role of FGF in the Formation and Treatment of Corneal Neovascularization
Frontiers in Pharmacology, 2020 Corneal neovascularization (CNV) is a sight-threatening disease usually associated with inflammatory, infectious, degenerative, and traumatic disorders of the ocular surface.
Mengji Chen +4 more
doaj +1 more source
Vascular protection by angiotensin receptor antagonism involves differential VEGF expression in both hemispheres after experimental stroke. [PDF]
PLoS ONE, 2011 We identified that the angiotensin receptor antagonist, candesartan, has profound neurovascular protective properties when administered after ischemic stroke and was associated with a proangiogenic state at least partly explained by vascular endothelial ...
Weihua Guan +9 more
doaj +1 more source