Results 201 to 210 of about 210,619 (269)

Growth Factor Signaling in Solid Organ Transplantation: A Conceptual Framework for Chronic Remodeling and Survival. [PDF]

Int J Mol Sci
Łacek U, Gaczyński C, Goszka M, Polikowska A, Serwin N, Dołęgowska B, Cecerska-Heryć E.   +6 more
europepmc   +1 more source

A Pathology‐Instructed Theranostic Platform with Mechanoadaptive and ROS‐Powered Nanobreathing Functions for Precision Myocardial Repair

Advanced Science, EarlyView.
We developed a pH responsive theranostic serum albumin hydrogel named BST, functionalized with MRI and CT probes and loaded with mitochondria targeted CAT‐SOD nanogels, that rapidly self repairs and mechanically stabilizes the infarcted myocardium, releases therapeutic nanogels and albumin under hypoxia induced acidosis to clear mitochondrial ROS ...
Zheng Luo, Cui Yang, Liuzhou Mao, Panqin Ma, Chiyu Jia, Karen Yuanting Tang, Xian Jun Loh, Yun‐Long Wu   +7 more
wiley   +1 more source

Postmenopausal osteoporosis and vascular calcification: The estrogen regulation network and calcification paradox. [PDF]

J Transl Int Med
Lin Y, Jiang P, Lv Y, Tian W.
europepmc   +1 more source

THBS1+ Macrophages Exacerbate Modic Changes via SDC4‐Dependent Activation of NLRP3 Inflammasome

Advanced Science, EarlyView.
The illustration of THBS1+ macrophages exacerbate MCs via SDC4‐dependent activation of the NLRP3 inflammasome. THBS1+ macrophage subpopulation was identified in MCs through single‐cell RNA sequencing. C. acnes and its metabolites activate THBS1 expression in macrophages via the TLR signaling pathway.
Xiangxi Kong, Qize Xue, Xiaoan Wei, Jie Li, Bao Huang, Weishao Chen, Zimin Cai, Tao Yang, Chengjun Yao, Jiayan Jin, Bohan Cai, Xuyang Zhang, Junhui Liu, Haihao Wu, Jian Chen, Zhi Shan, Fengdong Zhao   +16 more
wiley   +1 more source

Role of Caveolae and Caveolin in Vascular Physiology and Pathology. [PDF]

J Am Heart Assoc
Zhang C, Hu W, Zhang J, Wang Z, Lu H.
europepmc   +1 more source

Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS) in Glioblastoma

Advanced Science, EarlyView.
ABSTRACT Glioblastoma (GBM) remains one of the most challenging brain malignancies due to the restrictive nature of the blood–brain barrier (BBB), which severely limits effective drug and gene delivery. To overcome this, we introduce Biodegradable Acoustic Targeting for Ultrasound‐Supported Gene Therapy (BATUS), a modular platform that enables safe ...
Gulsah Erel‐Akbaba, Jinyoung Park, Achal Duhoon, Cao Thuy Giang Nguyen, Nitu Bhaskar, Sumanta Kumar Karan, Hasan Akbaba, Parbeen Singh, Thi Bao Tram Tran, Yuhui Zhu, Zhiming Li, I'jaaz Muhammad, Xiaojun Zhang, Hoang Quan Truong, A. Daniel Davidar, Elizabeth Schmitzer, Vikas N. Vattipally, Angelica F. Lopez, Patrick Kramer, Victor M. Quiroz, Ben Bykov, Claire Hao, Amir Manbachi, Nicholas Theodore, Joshua C. Doloff, Thanh D. Nguyen   +25 more
wiley   +1 more source

Bleomycin ElectroScleroTherapy (BEST): mechanistic parallels to electrochemotherapy, experimental models, and unresolved questions. [PDF]

Radiol Oncol
Lisec B, Cemazar M, Muir T, Omerzel M, Jesenko T, Markelc B, Groselj A, Dezman R, Stabuc M, Kuhelj D, Sersa G.   +10 more
europepmc   +1 more source

From bench to bed: The evolution of anti-vascular endothelial growth factor therapies. [PDF]

Indian J Ophthalmol
Sen A, Kohli G, Agarwal A, Chauhan R.
europepmc   +1 more source

Targeting IL-1β: a potential strategy for alleviating the immunopathology of aortic aneurysms. [PDF]

Front Immunol
Zhang F, Liao Y, Zhao D, Guo J.
europepmc   +1 more source