Results 211 to 220 of about 670,193 (365)

Current Advances of Antibacterial Biomaterials for Bone Regeneration

Advanced Materials Interfaces, EarlyView.
Effective treatment of infectious bone defects requires not only robust bone regeneration, but also the elimination of bacterial infection. This review highlights current cutting‐edge concepts and innovations in synthetic bone repair biomaterials and antibacterial bone repair materials, aiming to promote clinical translation and inspire broader ...
Xueping Kong, Xue Zhang, Ying Wang, Ben Zhang   +3 more
wiley   +1 more source

Progress and Application of Multifunctional Hydrogel in Radioactive Skin Injury

Advanced Materials Interfaces, EarlyView.
This review examines healing challenges in radiation‐wound injuries, where ionizing radiation impairs immune and tissue repair processes. Hydrogels, with their biocompatibility, antimicrobial properties, and drug delivery capabilities, present a transformative solution. It compares hydrogel efficacy in radiation‐induced versus common wounds, highlights
Xinyue Cui, Jingyi Wang, Xinyi Xu, Xiqian Cao, Yingtang Zhou, Jiaming Guo   +5 more
wiley   +1 more source

Tuning the Morphological Properties of Granular Hydrogels to Control Lymphatic Capillary Formation

Advanced Materials Interfaces, EarlyView.
Tuning the morphological properties of granular hydrogels is essential to generate robust lymphatic capillary networks that express key lymphatic gene and protein markers. The study demonstrates that 3D in vitro lymphatic tube formation is controlled not by the mechanical properties of the gel, but by the pore size and topology (periodicity) of the gel
Daniel Montes, Sanjoy Saha, Angela Taglione, Donghyun Paul Jeong, Liao Chen, Fei Fan, Hsueh‐Chia Chang, Donny Hanjaya‐Putra   +7 more
wiley   +1 more source

Growth Factor‐Loaded Mesoporous Silica Particles, Incorporated in Electrospun PCL Fibres, Provide Topographical and Chemical Cues for Tendon Tissue Engineering

Advanced Materials Technologies, EarlyView.
Electrospinning enables the hierarchical assembly of nanofiber‐based scaffolds for tissue engineering. However, encapsulated proteins often undergo structural changes. This study used mesoporous silica nanoparticles (MSNs) as protective carriers, mitigating protein denaturation and supporting controlled release.
Vera Citro, Marta Clerici, Matthew T. Shephard, Tina P. Dale, Aldo R. Boccaccini, Nicholas R. Forsyth   +5 more
wiley   +1 more source

Insights on Advances in 3D Bioprinting for Peripheral Nerve Regeneration

Advanced Therapeutics, EarlyView.
Peripheral nerve injury is a common condition due to trauma that significantly impacts the life of the affected individual. This review explores the anatomy, classification, and pathophysiology of peripheral nerve injuries. It also discusses various types of nerve conduits and presents a detailed review of 3D bioprinted nerve conduits used in both in ...
Nasera Rizwana, Samartha M C, Ashwath Acharya, Goutam Thakur, Manasa Nune, Vipul Agarwal   +5 more
wiley   +1 more source

Accelerated Bone Healing via Electrical Stimulation

Advanced Science, EarlyView.
Electrical stimulation significantly impacts bone healing by enhancing osteoblast proliferation, differentiation, and vascularization through calmodulin/calcineurin/NFAT signaling. It also boosts macrophage function and cell migration, presenting a comprehensive approach to accelerating bone repair.
Jianfeng Sun, Wenqing Xie, Yuxiang Wu, Zhou Li, Yusheng Li   +4 more
wiley   +1 more source

Inhalable Hsa‐miR‐30a‐3p Liposomes Attenuate Pulmonary Fibrosis

Advanced Science, EarlyView.
The study explores inhalable hsa‐miR‐30a‐3p‐loaded liposomes as a treatment for bleomycin‐induced pulmonary fibrosis in mice. Hsa‐miR‐30a‐3p is electroporated into liposomes and formulated into a dry powder for inhalation. Delivered via dry powder inhalation, it improves pulmonary function, promotes myofibroblast de‐differentiation by targeting CNPY2 ...
Shuo Liu, Kristen D. Popowski, Christina M. Eckhardt, Weihang Zhang, Junlang Li, Yujia Jing, Dylan Silkstone, Elizabeth Belcher, Megan Cislo, Shiqi Hu, Halle Lutz, Asma Ghodsi, Mengrui Liu, Phuong‐Uyen C. Dinh, Ke Cheng   +14 more
wiley   +1 more source

Advances in Microfluidic Cochlea‐On‐A‐Chip

Advanced Science, EarlyView.
This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen, Shanying Han, Weiwei He, Wen Yang, Xinghua Tang, Xiaolong Zhao, Xinghong Liu, Zhenhua Shao, Lin Cheng, Yu Zhao, Jiangang Fan   +10 more
wiley   +1 more source

Apoptotic Vesicles Derived from Mesenchymal Stem Cells Ameliorate Hypersensitivity Responses via Inducing CD8+ T Cells Apoptosis with Calcium Overload and Mitochondrial Dysfunction

Advanced Science, EarlyView.
The therapeutic potential of ApoVs derived from stem cells from human exfoliated deciduous teeth (SHED‐ApoVs) in the treatment of CD8+ T cell‐mediated hypersensitivity reactions is noteworthy. SHED‐ApoVs are capable of fusing with the plasma membrane of CD8+ T cells, which subsequently triggers a series of events characterized by calcium overload ...
Anqi Liu, Peng Peng, Changze Wei, Fanhui Meng, Xiaoyao Huang, Peisheng Liu, Siyuan Fan, Xinyue Cai, Meiling Wu, Zilin Xuan, Qing Liu, Xinyu Qiu, Zhenlai Zhu, Hao Guo   +13 more
wiley   +1 more source

Expression of Vascular Endothelial Growth Factor (VEGF) and its Receptors (Flt-1 and Flk-1) following Permanent and Transient Occlusion of the Middle Cerebral Artery in the Rat

Journal of Neuropathology and Experimental Neurology, 1998
F. Lennmyr, K. Ata, K. Funa, Y. Olsson, A. Térent   +4 more
semanticscholar   +1 more source