Results 61 to 70 of about 666,578 (361)

Expression and Functions of the Vascular Endothelial Growth Factors and Their Receptors in Human Basophils [PDF]

open access: yesThe Journal of Immunology, 2006
Abstract Angiogenesis is a multistep complex phenomenon critical for several inflammatory and neoplastic disorders. Basophils, normally confined to peripheral blood, can infiltrate the sites of chronic inflammation. In an attempt to obtain insights into the mechanism(s) underlying human basophil chemotaxis and its role in inflammation ...
DE PAULIS, AMATO   +12 more
openaire   +8 more sources

Endothelial platelet-derived growth factor-mediated activation of smooth muscle platelet-derived growth factor receptors in pulmonary arterial hypertension

open access: yesPulmonary Circulation, 2020
Platelet-derived growth factor is one of the major growth factors found in human and mammalian serum and tissues. Abnormal activation of platelet-derived growth factor signaling pathway through platelet-derived growth factor receptors may contribute to ...
Kang Wu   +21 more
doaj   +1 more source

Advances in the molecular regulation of endothelial BMP9 signalling complexes and implications for cardiovascular disease [PDF]

open access: yes, 2019
Bone morphogenetic protein 9 (BMP9), a member of the transforming growth factor (TGF) superfamily is a circulating vascular quiescence and endothelial-protective factor, accounting for the majority of BMP activity in plasma.
Guo, Jingxu   +3 more
core   +1 more source

The relationship between microvessel density, proliferative activity and expression of vascular endothelial growth factor-A and its receptors in eutopic endometrium and endometriotic lesions.

open access: yesReproduction, 2006
Studies were performed to elucidate the possible relationship between microvessel density, proliferative activity and angiogenesis in eutopic endometrium from women with and without endometriosis and peritoneal endometriotic lesions. The question whether
V. Bourlev   +5 more
semanticscholar   +1 more source

Unjamming and nematic flocks in endothelial monolayers during angiogenesis : theoretical and experimental analysis [PDF]

open access: yes, 2018
Angiogenesis is the complex process by which new blood vessels develop from an existing vasculature in order to supply nutrients and/or metabolites to tissues, playing a fundamental role in many physiological and pathological conditions such as embryogenesis and tissue repair or tumour growth.
arxiv   +1 more source

Mathematical modeling of glioma invasion and therapy approaches via kinetic theory of active particles [PDF]

open access: yesarXiv, 2022
A multiscale model for glioma spread in brain tissue under the influence of vascularization and vascular endothelial growth factors is proposed. It accounts for the interplay between the different components of the neoplasm and the healthy tissue and it investigates and compares various therapy approaches.
arxiv  

VEGFR-3 fusion proteins [PDF]

open access: yes, 2008
The present invention provides materials and methods for antagonizing the function of vascular endothelial growth factor receptors, platelet derived growth factor receptors and other receptors. Soluble binding constructs able to bind vascular endothelial
Alitalo, Kari Kustaa   +1 more
core  

Expression of vascular endothelial growth factor receptors 1, 2 and 3 in placentas from normal and complicated pregnancies.

open access: yesMolecular human reproduction, 2001
Extensive angiogenesis and invasion of the maternal decidua by trophoblasts are essential for the development and function of the placenta. Vascular endothelial growth factors (VEGF), placenta growth factor (PlGF) and their receptors VEGFR-1/Flt-1, VEGFR-
Satu Helske   +5 more
semanticscholar   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Rational Design of Antiangiogenic Helical Oligopeptides Targeting the Vascular Endothelial Growth Factor Receptors

open access: yesFrontiers in Chemistry, 2019
Tumor angiogenesis, essential for cancer development, is regulated mainly by vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs), which are overexpressed in cancer cells.
Simone Zanella   +16 more
doaj   +1 more source

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