Results 101 to 110 of about 15,888 (236)

The impact of pregestational stress on neurodevelopment: Implications for autism spectrum disorder and attention‐deficit/hyperactivity disorder

The Journal of Physiology, EarlyView.
Abstract figure legend Pregestational stress modifies germ‐cell epigenetic information, resulting in GABAergic dysfunction and E/I imbalance in the developing brain, thereby increasing susceptibility to ASD‐and ADHD‐related neurodevelopmental abnormalities in offspring.
Samaneh Ahmadian‐Moghadam, Ehsan Saboory, Shiva Roshan‐Milani   +2 more
wiley   +1 more source

Modulation by vasoactive intestinal peptide (VIP) of serotonin receptors in membranes from rat hippocampus

, 1983
The vasoactive intestinal peptide (VIP) has been located in various structures of the rat brain, but few actions of the peptide have been reported as yet. Because VIP might interact with classical neurotransmitter systems in the central nervous system as
WH Rostene, BS McEwen, CT Fischette
core   +1 more source

Development by Genetic Immunization of Monovalent Antibodies Against Human Vasoactive Intestinal Peptide Receptor 1 (VPAC1), New Innovative, and Versatile Tools to Study VPAC1 Receptor Function

Frontiers in Endocrinology, 2018
Multi-membrane spanning proteins, such as G protein-coupled receptors (GPCRs) and ion channels, are extremely difficult to purify as native proteins. Consequently, the generation of antibodies that recognize the native conformation can be challenging. By
Xavier Peyrassol, Toon Laeremans, Toon Laeremans, Toon Laeremans, Vannessa Lahura, Maja Debulpaep, Maja Debulpaep, Maja Debulpaep, Hassan El Hassan, Hassan El Hassan, Hassan El Hassan, Jan Steyaert, Jan Steyaert, Marc Parmentier, Marc Parmentier, Ingrid Langer   +15 more
doaj   +1 more source

Interaction of a bovine thymic peptide extract with vasoactive intestinal peptide (VIP) receptors

Bioscience Reports, 1986
Bovine t hymic peptide extract (1–100 μg/ml) is shown to completely inhibit the binding of [125I]VIP to rat blood mononuclear cells, lymphoid cells of spleen, and liver plasma membranes. In the three models, the bovine thymic peptide extract inhibits [125I]VIP binding with a potency that is 4000–7000 times lower than that of the native VIP, on a weight
J M, Guerrero, R, Goberna, P, Molinero, J, Jimenez, J R, Calvo   +4 more
openaire   +2 more sources

Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions

MedComm, Volume 7, Issue 7, July 2026.
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An, Yi An, Mengwei Chen, Longlong Wu, Rong Wang   +4 more
wiley   +1 more source

Vasoactive intestinal peptide receptor-based imaging and treatment of tumors

International Journal of Oncology, 2014
Vasoactive intestinal peptide receptors (VIPRs) are members of the G-protein-coupled receptor superfamily. These receptors are overexpressed in many common malignant tumors and play a major role in the progression and angiogenesis of a number of malignancies.
Bo, Tang, Xin, Yong, Rui, Xie, Qian-Wei, Li, Shi-Ming, Yang   +4 more
openaire   +3 more sources

Fecal Proteomics Suggest Potential Biomarkers for Non‐Alcoholic Fatty Liver Disease and Steatohepatitis

PROTEOMICS – Clinical Applications, Volume 20, Issue 4, July 2026.
ABSTRACT Background and aims Non‐alcoholic Fatty Liver Disease (NAFLD) affects about a quarter of the world's population. Liver biopsy remains the gold standard for diagnosing the progressive form of NAFLD called Non‐alcoholic Steatohepatitis (NASH) but it is invasive, prone to sampling errors and observer variability, and impractical for widespread ...
Anna Negroni, Luisa Pieroni, Noemi Fiaschini, Francesca Palone, Mariateresa Mancuso, Roberta Vitali   +5 more
wiley   +1 more source

Vasoactive Intestinal Peptide Changes the Frequency and Force of Myocardial Contraction in Rats

, 2020
© 2020, Springer Science+Business Media, LLC, part of Springer Nature. We studied the effect of non-selective agonist of VIP receptors of vasoactive intestinal polypeptide in different concentrations on the frequency, force, and duration of isometric ...
Аnikina, Zefirov L., Leonov N.V., Zverev A.   +3 more
core  

Endothelial Netrin‐4 regulates oligodendrocyte precursor cell proliferation and differentiation via ET‐1 signaling in preterm white matter injury

Brain Pathology, Volume 36, Issue 4, July 2026.
Our findings show early increased Netrin‐4 in mice with PWMI boosts angiogenesis and OPCs proliferation. Later, high levels hinder OPCs differentiation into mature cells, impairing myelination. It may act by stimulating ET‐1 secretion. Abstract Perinatal hypoxia–ischemia is a leading cause of preterm white matter injury (PWMI), yet mechanisms ...
Fuxing Dong, Weixing Yan, Qiqi Meng, Xueli Song, Bing Cheng, Yaping Liu, Yanan Liu, Chao Ren, Ruiqin Yao   +8 more
wiley   +1 more source

Prejunctional inhibition of vasoactive intestinal peptide release

, 1987
The role of vasoactive intestinal peptide (VIP) and its homologue, peptide histidine isoleucine (PHI), as neurotransmitters of inhibitory motor nerves of the gut, were examined in strips of guinea pig taenia coli and gastric fundic muscle.
J. R. Grider, G. M. Makhlouf
core   +1 more source