Results 181 to 190 of about 15,888 (236)

Receptors for vasoactive intestinal peptide and secretin on rat pancreatic acini

open access: yesAmerican Journal of Physiology-Gastrointestinal and Liver Physiology, 1984
In dispersed acini from rat pancreas, binding of 125I-labeled vasoactive intestinal peptide and 125I-labeled secretin was relatively rapid, reversible, saturable, and temperature dependent. The rate of dissociation of bound 125I-labeled peptide was not a function of the concentration of free vasoactive intestinal peptide or secretin, indicating that ...
B M, Bissonnette   +4 more
openaire   +3 more sources

Characterization of vasoactive intestinal peptide receptors in rat seminal vesicle

open access: yesAmerican Journal of Physiology-Endocrinology and Metabolism, 1991
Receptors for vasoactive intestinal peptide (VIP) in membranes from rat seminal vesicle were examined using 125I-labeled VIP as ligand. The receptor binding was rapid, reversible, saturable, specific, and dependent on temperature and membrane concentration.
L G, Guijarro   +2 more
openaire   +3 more sources

Characterization of vasoactive intestinal peptide receptors on rat alveolar macrophages

open access: yesAmerican Journal of Physiology-Lung Cellular and Molecular Physiology, 1994
In view of the evidence that vasoactive intestinal peptide (VIP) may modulate acute inflammatory injury in the lung, we investigated the presence and characteristics of VIP receptors on alveolar macrophages (AMs). We examined the binding of monoiodinated [Tyr(125I)10]-labeled VIP (125I-VIP) to rat AMs (> 96% pure), obtained from Sprague-Dawley rats
H, Sakakibara, K, Shima, S I, Said
openaire   +3 more sources

Vasoactive intestinal peptide and its receptors in fetuses with cystic fibrosis

open access: yesAmerican Journal of Physiology-Gastrointestinal and Liver Physiology, 1989
Fetuses were investigated to establish whether vasoactive intestinal peptide (VIP) and its receptors are involved in the basic biochemical defect causing cystic fibrosis (CF). The intestine was used as a target for the disease and the liver as control.
E, Chastre   +6 more
openaire   +3 more sources

Distribution of vasoactive intestinal peptide and its receptors in the arteries of the rabbit

open access: yesJournal of Surgical Research, 1989
Vasoactive intestinal peptide (VIP) is a widely distributed neurotransmitter whose dilatory effects on vascular smooth muscle are believed to be mediated via specific receptors. To determine the possible role of VIP in regulating specific vascular beds, we examined the relationship between arterial wall VIP content as determined by radioimmunoassay and
A N, Sidawy   +6 more
openaire   +3 more sources

Autoradiographic mapping of [mono[125I]iodo-Tyr10, MetO17]vasoactive intestinal peptide binding sites in the rat brain

open access: yesNeuroscience, 1987
The distribution of vasoactive intestinal peptide binding sites in the rat brain was examined by in vitro autoradiography on slide-mounted sections. A fully characterized monoiodinated form of vasoactive intestinal peptide (M-[125I]VIP) previously shown ...
P R Hof   +2 more
exaly   +3 more sources

Characterization of vasoactive intestinal peptide receptors in human liver

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1994
The stoichiometric, pharmacological and molecular properties of vasoactive intestinal peptide (VIP) receptors have been analyzed in human liver membranes and compared in parallel with those in rat liver membranes. The binding of [125I]VIP was rapid, saturable and specific.
N, Rodríguez-Henche   +3 more
openaire   +2 more sources

Vasoactive Intestinal Peptide Receptor Expression on Human Lymphoblasts

Journal of Pediatric Hematology/Oncology, 1992
This study was designed to determine which (if any) subtypes of leukemic blasts express a functional receptor for vasoactive intestinal peptide (VIP). Blasts harvested from bone marrow of 38 newly diagnosed patients were classified as acute lymphocytic leukemia (CALLA + pre-B-cell leukemia, CALLA-, pre-B-cell leukemia, T-cell leukemia) or acute myeloid
M S, O'Dorisio   +5 more
openaire   +2 more sources

Presence of Vasoactive Intestinal Peptide Receptors in Nasal Mucosa

Skin Pharmacology, 2009
In recent years several tachykinins have been identified in the airway sensory nerves. Since the physiological and pathophysiological effects of neuropeptides depend on their functionally relevant concentrations and presence of specific receptors in the target tissue, specimens of enlarged turbinates and nasal polyps were removed in 11 patients and ...
S, Agha-Mir-Salim   +4 more
openaire   +2 more sources

Autoradiographic visualization of CNS receptors for vasoactive intestinal peptide

Peptides, 1986
Receptors for VIP were characterized in the rat CNS. 125I-VIP bound with high affinity to rat brain slices. Binding was time dependent and specific. Pharmacology studies indicated that specific 125I-VIP binding was inhibited with high affinity by VIP and low affinity by secretin and PHI.
M M, Shaffer, T W, Moody
openaire   +2 more sources

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