Characterization of vasoactive intestinal peptide receptors in rat seminal vesicle
American Journal of Physiology-Endocrinology and Metabolism, 1991Receptors for vasoactive intestinal peptide (VIP) in membranes from rat seminal vesicle were examined using 125I-labeled VIP as ligand. The receptor binding was rapid, reversible, saturable, specific, and dependent on temperature and membrane concentration.
L G, Guijarro +2 more
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Vasoactive Intestinal Peptide in Thymus: Synthesis, Receptors and Biological Actions
Neuroimmunomodulation, 1999Evidence summarized in this report indicates that thymocytes produce and secrete VIP. Moreover, different stimuli such as Con A, LPS and anti-TCR antibody induce a significant increase in VIP production by thymocytes. In addition, proinflammatory cytokines such as IL-1, IL-6 and TNF-α, but not IL-2, stimulate in a similar time-dependent manner VIP ...
M, Delgado +3 more
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Vasoactive intestinal peptide and its receptors in fetuses with cystic fibrosis
American Journal of Physiology-Gastrointestinal and Liver Physiology, 1989Fetuses were investigated to establish whether vasoactive intestinal peptide (VIP) and its receptors are involved in the basic biochemical defect causing cystic fibrosis (CF). The intestine was used as a target for the disease and the liver as control.
E, Chastre +6 more
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Receptors for vasoactive intestinal peptide on isolated human sweat glands
Peptides, 1986Human sweat gland function is predominantly under cholinergic control. Sweat secretion may also be regulated by Vasoactive Intestinal Peptide (VIP), which coexists with acetylcholine in nerves to sweat gland acini and ducts. We have examined the expression of VIP receptors on isolated human eccrine sweat glands.
P, Heinz-Erian, S, Paul, S I, Said
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The Airway and Vasoactive Intestinal Peptide Autoantibodies and Receptors
2020This chapter outlines observations on human autoantibodies directed against vasoactive intestinal peptide (VIP), the functional properties of these autoantibodies, and their relevance to disease; and characteristics, regulatory features, and signal-transducing pathways utilized by the VIP receptor in guinea pig lung.
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Characterization of Vasoactive Intestinal Peptide (VIP) receptors in mammalian lung
Peptides, 1986125I-VIP bound specifically to sites on human, rat, guinea pig, and rabbit lung membranes with a dissociation constant (KD) of 60-200 pM and binding site maxima of 200-800 fmol/mg of protein. The presence of a second lower affinity site was detected but not investigated further.
K E, Dickinson +4 more
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The vasoactive intestinal peptide (VIP) receptor: recent data and hypothesis
Biochimie, 1988Vasoactive intestinal peptide (VIP) is a neuropeptide with a broad range of biological activities in various tissues. After interaction with its membrane receptor, VIP generally induces a very large increase in the intracellular cyclic AMP level. Receptors for VIP have been described in numerous tissues and cell lines. The first results on VIP receptor
J, Luis +4 more
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Vasoactive intestinal peptide receptor localization in rat forebrain by autoradiography
Neuroscience Letters, 1985Vasoactive intestinal peptide (VIP) receptors were localized in rat forebrain by in vitro labeling light microscopic autoradiography with 125I-labeled VIP. Binding sites for VIP were found in discrete areas of rat forebrain including lamina I of the neocortex and pyriform cortex, caudate-putamen, the hippocampus and molecular layer of the dentate gyrus,
E B, De Souza, H, Seifert, M J, Kuhar
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Ontogeny of vasoactive intestinal peptide receptors in rat ventral prostate
General Pharmacology: The Vascular System, 19941. The stimulatory effect of VIP on rat prostatic adenylyl cyclase changes during postnatal development. It peaks at 2 months (peripubertal period), remains in a plateau between 3 and 12 months (adult period), and decreases at 24 months (old period). 2.
M G, Juarranz +4 more
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Receptors for vasoactive intestinal peptide and secretin on rat pancreatic acini
American Journal of Physiology-Gastrointestinal and Liver Physiology, 1984In dispersed acini from rat pancreas, binding of 125I-labeled vasoactive intestinal peptide and 125I-labeled secretin was relatively rapid, reversible, saturable, and temperature dependent. The rate of dissociation of bound 125I-labeled peptide was not a function of the concentration of free vasoactive intestinal peptide or secretin, indicating that ...
B M, Bissonnette +4 more
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