Expression of vasoactive intestinal peptide (VIP) receptors in human uterus
Peptides, 2000We show the existence of functional vasoactive intestinal peptide (VIP) receptors in normal human female genital tract (endometrium, myometrium, ovary and Fallopian tube) as well as in leiomyoma (a frequent uterine pathology). The correlation between VIP binding and stimulation of adenylyl cyclase activity for all studied tissues was linear (r = 0.86 ...
A M, Bajo +5 more
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Receptors for vasoactive intestinal peptide and secretin on rat pancreatic acini
American Journal of Physiology-Gastrointestinal and Liver Physiology, 1984In dispersed acini from rat pancreas, binding of 125I-labeled vasoactive intestinal peptide and 125I-labeled secretin was relatively rapid, reversible, saturable, and temperature dependent. The rate of dissociation of bound 125I-labeled peptide was not a function of the concentration of free vasoactive intestinal peptide or secretin, indicating that ...
B M, Bissonnette +4 more
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Characterization and Localization of Vasoactive Intestinal Peptide Receptors in the Rat Lung
Endocrinology, 1984Experiments were performed to characterize vasoactive intestinal peptide (VIP) receptors in rat lung and to study their localization by means of light and electron microscope autoradiography. [125I]Iodo-VIP binding to lung homogenate was inhibited by synthetic VIP, [Val5]secretin, secretin, and 7-27 secretin with half-maximal inhibition (ID50) values ...
P, Leroux +4 more
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Characterization of vasoactive intestinal peptide receptors in canine liver membranes
Biochemical Pharmacology, 1994The binding characteristics of vasoactive intestinal peptide (VIP) in the liver membranes of the dog were examined using radioligand binding assay with 125I-VIP and unlabelled peptides and results were compared with those from the rat. The binding of VIP to canine liver membranes occurred in a reversible, saturable, specific and temperature-dependent ...
T, Kiso +4 more
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Vasoactive intestinal peptide receptor expression in chronic periapical lesions
International Endodontic Journal, 2007AbstractAim To use radioreceptor analysis for evaluating whether vasoactive intestinal peptide (VIP) receptors are present in chronic periapical lesions and to determine whether differences in its expression are found according to the size of the lesions.Methodology Twelve periapical lesions were obtained from teeth diagnosed with chronic apical ...
J, Caviedes-Bucheli +6 more
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Receptors for vasoactive intestinal peptide on isolated human sweat glands
Peptides, 1986Human sweat gland function is predominantly under cholinergic control. Sweat secretion may also be regulated by Vasoactive Intestinal Peptide (VIP), which coexists with acetylcholine in nerves to sweat gland acini and ducts. We have examined the expression of VIP receptors on isolated human eccrine sweat glands.
P, Heinz-Erian, S, Paul, S I, Said
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Vasoactive intestinal peptide receptor scintigraphy.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1995This study presents the biodistribution, safety and absorbed dose of 123I-VIP administered to 18 patients with intestinal adenocarcinomas or endocrine tumors.To achieve high-specific activity, 123I-VIP was purified by HPLC. Following intravenous administration of 123I-VIP (172 +/- 17 MBq (4.65 +/- 0.5 mCi); < 300 pmole ( < 1 microgram)/patient ...
I, Virgolini +9 more
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Characterization of Vasoactive Intestinal Peptide (VIP) receptors in mammalian lung
Peptides, 1986125I-VIP bound specifically to sites on human, rat, guinea pig, and rabbit lung membranes with a dissociation constant (KD) of 60-200 pM and binding site maxima of 200-800 fmol/mg of protein. The presence of a second lower affinity site was detected but not investigated further.
K E, Dickinson +4 more
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Role of phospholipids in the binding activity of vasoactive intestinal peptide receptors
Experientia, 1985Phospholipase digestion of rat intestinal epithelial cell membranes was performed in order to study the influence of membrane phospholipids on the binding activity of VIP receptors. Phospholipases A2 and C strongly (ED50 congruent to 4 X 10(-2) and 4 X 10(-1) micrograms/ml, respectively) and rapidly reduced 125I-VIP binding to membranes whereas ...
A, Sarrieau, N, Boige, M, Laburthe
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Characterization of vasoactive intestinal peptide receptors in rat seminal vesicle
American Journal of Physiology-Endocrinology and Metabolism, 1991Receptors for vasoactive intestinal peptide (VIP) in membranes from rat seminal vesicle were examined using 125I-labeled VIP as ligand. The receptor binding was rapid, reversible, saturable, specific, and dependent on temperature and membrane concentration.
L G, Guijarro +2 more
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