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Characterization of vasoactive intestinal peptide receptors in human liver

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1994
The stoichiometric, pharmacological and molecular properties of vasoactive intestinal peptide (VIP) receptors have been analyzed in human liver membranes and compared in parallel with those in rat liver membranes. The binding of [125I]VIP was rapid, saturable and specific.
N, Rodríguez-Henche   +3 more
openaire   +2 more sources

Vasoactive Intestinal Peptide Receptor Expression on Human Lymphoblasts

Journal of Pediatric Hematology/Oncology, 1992
This study was designed to determine which (if any) subtypes of leukemic blasts express a functional receptor for vasoactive intestinal peptide (VIP). Blasts harvested from bone marrow of 38 newly diagnosed patients were classified as acute lymphocytic leukemia (CALLA + pre-B-cell leukemia, CALLA-, pre-B-cell leukemia, T-cell leukemia) or acute myeloid
M S, O'Dorisio   +5 more
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Presence of Vasoactive Intestinal Peptide Receptors in Nasal Mucosa

Skin Pharmacology, 2009
In recent years several tachykinins have been identified in the airway sensory nerves. Since the physiological and pathophysiological effects of neuropeptides depend on their functionally relevant concentrations and presence of specific receptors in the target tissue, specimens of enlarged turbinates and nasal polyps were removed in 11 patients and ...
S, Agha-Mir-Salim   +4 more
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Autoradiographic visualization of CNS receptors for vasoactive intestinal peptide

Peptides, 1986
Receptors for VIP were characterized in the rat CNS. 125I-VIP bound with high affinity to rat brain slices. Binding was time dependent and specific. Pharmacology studies indicated that specific 125I-VIP binding was inhibited with high affinity by VIP and low affinity by secretin and PHI.
M M, Shaffer, T W, Moody
openaire   +2 more sources

Receptors for vasoactive intestinal peptide and secretin on small intestinal epithelial cells

American Journal of Physiology-Gastrointestinal and Liver Physiology, 1980
Binding of 125I-labeled vasoactive intestinal peptide (VIP) to dispersed enterocytes prepared from guinea pig small intestine was saturable, temperature dependent, and reversible, and reflected interaction of the labeled peptide with a single class of binding sites. Each enterocyte possessed approximately 60,000 binding sites and binding of the tracer
H J, Binder, G F, Lemp, J D, Gardner
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Assays for Vasoactive Intestinal Peptide Receptor

1991
Publisher Summary This chapter discusses the methods for characterization of the number and affinity of vasoactive intestinal peptide (VIP) receptor sites on intact cells, in membrane preparations, and in solubilized membranes. The chapter also describes experiments for determining the pharmacologic specificity of peptide receptors, and for using ...
Gail D. Wenger   +2 more
openaire   +1 more source

Vasoactive intestinal peptide (VIP) receptors in the canine gastrointestinal tract

Peptides, 1988
Vasoactive intestinal peptide (VIP) is a putative neurotransmitter in both the brain and peripheral tissues. To define possible target tissues of VIP we have used quantitative receptor autoradiography to localize and quantify the distribution of 125I-VIP receptor binding sites in the canine gastrointestinal tract.
R P, Zimmerman   +5 more
openaire   +2 more sources

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