Results 131 to 140 of about 53,933 (291)
Tolvaptan and its potential in the treatment of hyponatremia
Therapeutics and Clinical Risk Management, 2008 Megan B Dixon, Y Howard LienDepartment of Medicine, University of Arizona, Arizona Kidney Disease and Hypertension Center, Tucson, Arizona, USAAbstract: Tolvaptan is a selective arginine vasopressin (AVP) V2 receptor blocker used to induce free water ...
Y Howard Lien, Megan B Dixon
doaj
Ouabain‐induced hypertension in rats: Mechanisms, variability and translational implications
Experimental Physiology, EarlyView.Abstract Ouabain‐induced hypertension is a multifactorial and condition‐dependent phenomenon involving coordinated actions across vascular, renal and central nervous system pathways. At the vascular level, ouabain inhibits Na⁺/K⁺‐ATPase, particularly the α2‐isoform, leading to elevated intracellular Ca2⁺, enhanced vasoconstriction and structural ...
Priscilla Rodrigues O. Feijó +1 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract Menopause increases the risk of hypertension in women, yet the factors contributing to this important change remain unclear. Because early life stress has persistent and sex‐specific consequences on health, we hypothesized that ageing reveals the latent effects of neonatal maternal separation (NMS) on cardiovascular homeostasis in female rats.
Danuzia Ambrozio‐Marques +6 more
wiley +1 more source
Mechanisms of haemoglobin mass expansion following heat stress
The Journal of Physiology, EarlyView.Abstract figure legend Theorised mechanisms of heat stress‐induced erythropoiesis which may facilitate the expansion of haemoglobin mass. A, acute: heat stress‐induced renal ischaemia. Redistribution of blood flow away from the kidneys to facilitate thermoregulation during heat stress could reduce renal oxygen delivery, subsequently lowering renal PO2${
Elliott J. Jenkins +4 more
wiley +1 more source
Pharmacological and neurophysiological aspects of space/motion sickness [PDF]
A motorized motion testing device modeled after a Ferris wheel was constructed to perform motion sickness tests on cats. Details of the testing are presented, and some of the topics covered include the following: xylazine-induced emesis; analysis of the ...
Crampton, George H., Lucot, James B.
core +1 more source
Management Strategies for Refractory Esophageal Varices
DEN Open, Volume 6, Issue 1, April 2026.ABSTRACT Refractory esophageal varices that are difficult to control or unresponsive to endoscopic treatment remain a major clinical challenge in the management of portal hypertension. This review provides a comprehensive overview of treatment strategies for these cases, along with a comparative analysis of the American Association for the Study of ...
Keita Maki, Hiroaki Haga, Yoshiyuki Ueno
wiley +1 more source
Developmental Psychobiology, Volume 68, Issue 2, March 2026.ABSTRACT Weaning is a stressful stage in the lives of young mammals. Early weaning, in particular, can lead to long‐lasting physiological and psychological changes. We investigated the effects of precocial weaning on anxiety, social behavior, cognition, and maternal behavior in adult African four‐striped mice (Rhabdomys dilectus chakae). Mice weaned at
Maria K Oosthuizen, Neville Pillay
wiley +1 more source
Food Frontiers, Volume 7, Issue 2, March 2026.Engineered probiotics secretes fusion proteins which potentially neutralized the toxins secreted by other microbial communities. ABSTRACT On a global scale, the escalating burden of infectious diseases, predominantly attributed to bacterial pathogens, especially drug‐resistant strains, has progressed into a critical concern for clinical management and ...
Indu Singh +11 more
wiley +1 more source
Tocolytic agents and the failure to improve neonatal outcomes
Pregnancy, Volume 2, Issue 2, March 2026.Abstract Premature delivery has long been a major problem in obstetrics. Increased perinatal morbidity and mortality as well as substantial health care costs, both short and long term, have driven the efforts to combat this complication. While multiple agents have been studied over the last 70 years leading to hundreds of publications and involving ...
Jack FitzSimmons, Emily Oliver
wiley +1 more source