Since early 2024, highly pathogenic avian influenza H5N1 viruses have been causing outbreaks in dairy cattle in the United States. Here, we compared the replicative capacity of A/dairy cattle/Texas/24-008749-001/2024 (H5N1; Cow-H5N1) isolated from a ...
Masaki Imai +11 more
doaj +1 more source
The Na+-K+-ATPase alpha subunit is an entry receptor for white spot syndrome virus
White spot syndrome virus (WSSV) is a debilitating viral pathogen that poses a significant threat to the global crustacean farming industry. It has a wide host tropism because it uses several receptors to facilitate its attachment and entry.
Junyi Zhou +8 more
doaj +1 more source
Co-Evolution of quasispecies: B-cell mutation rates maximize viral error catastrophes
Co-evolution of two coupled quasispecies is studied, motivated by the competition between viral evolution and adapting immune response. In this co-adaptive model, besides the classical error catastrophe for high virus mutation rates, a second ...
A. Aigner +29 more
core +1 more source
Technology and Biological Weapons: Future Threats [PDF]
Ye
Davison, N., Millett, P., Nixdorff, K.
core
5-HT6R Viral Vector-Mediated Indirect Pathway Activation in the Dorsolateral Striatum: A Discussion on Basal Ganglia Habitual and Goal-Directed Circuits [PDF]
Altering maladaptive behavioral tendencies is relevant for clinical interventions, making research on underlying mechanisms of habit essential. Mechanisms of habit are explored here with differential activation of the indirect pathway in the basal ...
Winn, Caleb S
core +1 more source
Transition between immune and disease states in a cellular automaton model of clonal immune response
In this paper we extend the Celada-Seiden (CS) model of the humoral immune response to include infectious virus and cytotoxic T lymphocytes (cellular response).
Abbas +26 more
core +2 more sources
Insights into mosquito-borne arbovirus receptors
The increasing global prevalence of mosquito-borne viruses has emerged as a significant threat to human health and life. Identifying receptors for these viruses is crucial for improving our knowledge of viral pathogenesis and developing effective ...
Jianying Liu +6 more
doaj +1 more source
APRIL:TACI axis is dispensable for the immune response to rabies vaccination. [PDF]
There is significant need to develop a single-dose rabies vaccine to replace the current multi-dose rabies vaccine regimen and eliminate the requirement for rabies immune globulin in post-exposure settings.
Alugupalli, Kishore R. +5 more
core +1 more source
Differences in virus receptor for type I and type II feline infectious peritonitis virus. [PDF]
Feline infectious peritonitis viruses (FIPVs) are classified into type I and type II serogroups. Here, we report that feline aminopeptidase N (APN), a cell-surface metalloprotease on the intestinal, lung and kidney epithelial cells, is a receptor for ...
Hohdatsu, T +4 more
core
Evolution of H7N9 highly pathogenic avian influenza virus in the context of vaccination
Human infections with the H7N9 influenza virus have been eliminated in China through vaccination of poultry; however, the H7N9 virus has not yet been eradicated from poultry.
Yujie Hou +18 more
doaj +1 more source

