Results 61 to 70 of about 235,128 (161)
Receptor specificity and transmission of H2N2 subtype viruses isolated from the pandemic of 1957. [PDF]
PLoS ONE, 2010 Influenza viruses of the H2N2 subtype have not circulated among humans in over 40 years. The occasional isolation of avian H2 strains from swine and avian species coupled with waning population immunity to H2 hemagglutinin (HA) warrants investigation of ...
Claudia Pappas +6 more
doaj +1 more source
Cellular receptors for mammalian viruses.
PLoS PathogensThe interaction of viral surface components with cellular receptors and other entry factors determines key features of viral infection such as host range, tropism and virulence.
Ana Valero-Rello +3 more
doaj +1 more source
RNA Viruses, Toll-Like Receptors, and Cytokines: The Perfect Storm?
Journal of Innate ImmunityBackground: The interactions between viruses and the host immune response are nuanced and intricate. The cytokine response arguably plays a central role in dictating the outcome of virus infection, balancing inflammation, and healing, which is
Sophia K. Stegeman +7 more
doaj +1 more source
CD155 on HIV-infected cells is not modulated by HIV-1 Vpu and Nef but synergizes with NKG2D ligands to trigger NK cell lysis of autologous primary HIV-infected cells [PDF]
, 2017 Activation of primary CD4(+) T cells induces the CD155, but not the CD112 ligands for the natural killer (NK) cell activation receptor (aNKR) CD226 [DNAX accessory molecule-1 (DNAM-1)].
Barker, Edward +5 more
core +2 more sources
Zika Virus Structure, Maturation, and Receptors [PDF]
The Journal of Infectious Diseases, 2017 The emergence of Zika virus (ZIKV) as a major public health threat has focused research on understanding virus biology and developing a suite of strategies for disease intervention. Recent advances in cryoelectron microscopy have accelerated structure-function studies of flaviviruses and of ZIKV in particular. Structures of the mature and immature ZIKV
Devika, Sirohi, Richard J, Kuhn
openaire +2 more sources
Cell Reports, 2019 Summary: JC polyomavirus (JCPyV) is a ubiquitous human pathogen that causes progressive multifocal leukoencephalopathy (PML). The entry receptors for JCPyV belong to the 5-hydroxytryptamine 2 receptor (5-HT2R) family, but how individual members of the ...
Benedetta Assetta +7 more
doaj +1 more source
SIMMUNE, a tool for simulating and analyzing immune system behavior
, 1999 We present a new approach to the simulation and analysis of immune system behavior. The simulations that can be done with our software package called SIMMUNE are based on immunological data that describe the behavior of immune system agents (cells ...
Mack, G., Meier-Schellersheim, M.
core +1 more source
TurboID-mediated proximity labeling technologies to identify virus co-receptors
Frontiers in Cellular and Infection MicrobiologyVirus receptors determine the tissue tropism of viruses and have a certain relationship with the clinical outcomes caused by viral infection, which is of great importance for the identification of virus receptors to understand the infection mechanism of ...
Bo Wang +5 more
doaj +1 more source
Distinct Roles for Sialoside and Protein Receptors in Coronavirus Infection
mBio, 2020 Coronaviruses (CoVs) are common human and animal pathogens that can transmit zoonotically and cause severe respiratory disease syndromes. CoV infection requires spike proteins, which bind viruses to host cell receptors and catalyze virus-cell membrane ...
Enya Qing +3 more
doaj +1 more source
Oligosaccharides as Receptors for JC Virus [PDF]
Journal of Virology, 2002 ABSTRACT JC virus (JCV) belongs to the polyomavirus family of double-stranded DNA viruses and in humans causes a demyelinating disease of the central nervous system, progressive multifocal leukoencephalopathy. Its hemagglutination activity and entry into host cells have been reported to depend on an N-linked glycoprotein containing sialic ...
Rika, Komagome +6 more
openaire +2 more sources