Results 41 to 50 of about 609,928 (307)

High affinity allele for the gene of FCGR3A is risk factor for HIV infection and progression. [PDF]

PLoS ONE, 2010
We investigated the genetics of Fc receptors, which function as activating receptors on immune cells and help to control HIV through antibody-mediated cellular cytotoxicity.
Bhawna Poonia, Gustavo H Kijak, C David Pauza   +2 more
doaj   +1 more source

Tolerance to mutations in the foot-and-mouth disease virus integrin-binding RGD region is different in cultured cells and in vivo and depends on the capsid sequence context. [PDF]

, 2008
Engineered RNAs carrying substitutions in the integrin receptor-binding Arg-Gly-Asp (RGD) region of foot-and-mouth disease virus (FMDV) were constructed (aa 141-147 of VP1 capsid protein) and their infectivity was assayed in cultured cells and suckling
Baranowski, Eric, Gutiérrez-Rivas, Monica, Pulido, Miguel R, Sobrino, Francisco, Sáiz, Margarita   +4 more
core   +3 more sources

Virus-Receptor Interactions and Receptor-Mediated Virus Entry into Host Cells [PDF]

, 2013
The virus particles described in the previous chapters of this book are vehicles that transmit the viral genome and the infection from cell to cell. To initiate the infective cycle, the viral genome must therefore translocate from the viral particle to the cell cytoplasm. Via distinct proteins or motifs in their outermost shell, the particles of animal
openaire   +3 more sources

Sequencing of rabies binding region on nicotinic acteylcholine receptor alpha subunits in four host species [PDF]

, 2013
• Rabies virus is known to bind to nicotinic acetylcholine receptors (nAchR) • The virus is known to bind to alpha 1 subunits nAchR • The virus binding region has been characterized in alpha 1 subunits of these receptors • Little research has been ...
Barnard, Karen
core  

The role of cellular adhesion molecules in virus attachment and entry [PDF]

, 2015
As obligate intracellular parasites, viruses must traverse the host-cell plasma membrane to initiate infection. This presents a formidable barrier, which they have evolved diverse strategies to overcome.
Bhella, David
core   +1 more source

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

A human coronavirus responsible for the common cold massively kills dendritic cells but not monocytes [PDF]

, 2012
Copyright @ 2012, American Society for Microbiology.Human coronaviruses are associated with upper respiratory tract infections that occasionally spread to the lungs and other organs.
A. Vabret, Abt, Arbour, Arbour, B. Nal, Bonavia, Caignard, Caignard, Callendret, Callow, Caux, Chapuis, Collins, de Swart, de Witte, Desforges, Desforges, Engelmayer, Esposito, F. Tangy, Ferlazzo, Gagneur, Geijtenbeek, Glew, H. Law, Hahm, Hamdorf, Herbst, Hoarau, J. Millet, Kramer, Kärber, Law, Legge, M. L. Albert, M. Mesel-Lemoine, MacDonald, Mahanty, Movassagh, Muller, N. Escriou, Nogueira, O'Doherty, Olweus, P.-O. Vidalain, Pacanowski, Piqueras, Rosenzwajg, Sallusto, Servet-Delprat, Servet-Delprat, Servet-Delprat, Sizun, Spearman, Spiegel, Thitithanyanont, Thornberry, V. Lorin, Vabret, Wang, Yang, Yeager   +61 more
core   +3 more sources

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan, Lydie Da Costa, Ludivine David Nguyen, Heloise Chosseler, Audrey Riquet, Benedicte Bruno, Melissa Barbati   +6 more
wiley   +1 more source

Respiratory virus infection up-regulates TRPV1, TRPA1 and ASICS3 receptors on airway cells.

PLoS ONE, 2017
Receptors implicated in cough hypersensitivity are transient receptor potential vanilloid 1 (TRPV1), transient receptor potential cation channel, Subfamily A, Member 1 (TRPA1) and acid sensing ion channel receptor 3 (ASIC3).
Shadia Omar, Rebecca Clarke, Haniah Abdullah, Clare Brady, John Corry, Hanagh Winter, Olivier Touzelet, Ultan F Power, Fionnuala Lundy, Lorcan P A McGarvey, S Louise Cosby   +10 more
doaj   +1 more source

Measles Virus Receptors and Tropism

Japanese Journal of Infectious Diseases, 2006
Measles virus (MV) is a member of the Morbillivirus genus in the Paramyxoviridae family. Human signaling lymphocyte activation molecule (SLAM) acts as a cellular receptor for MV. SLAM is expressed on immature thymocytes, activated lymphocytes, macrophages and mature dendritic cells.
Yusuke, Yanagi, Makoto, Takeda, Shinji, Ohno, Fumio, Seki   +3 more
openaire   +2 more sources