Results 21 to 30 of about 397,393 (265)

Essential roles for soluble virion-associated heparan sulfonated proteoglycans and growth factors in human papillomavirus infections. [PDF]

PLoS Pathogens, 2012
A subset of human papillomavirus (HPV) infections is causally related to the development of human epithelial tumors and cancers. Like a number of pathogens, HPV entry into target cells is initiated by first binding to heparan sulfonated proteoglycan ...
Zurab Surviladze, Agnieszka Dziduszko, Michelle A Ozbun   +2 more
doaj   +1 more source

GateView: A Multi-Omics Platform for Gene Feature Analysis of Virus Receptors within Human Normal Tissues and Tumors

Biomolecules
Viruses are obligate intracellular parasites that rely on cell surface receptor molecules to complete the first step of invading host cells. The experimental method for virus receptor screening is time-consuming, and receptor molecules have been ...
Yang Sun, Zi-Liang Huang, Wen-Xin Chen, Yi-Feng Zhang, Hao-Tian Lei, Qiao-Juan Huang, Zhao-Rong Lun, Liang-Hu Qu, Ling-Ling Zheng   +8 more
doaj   +1 more source

Comparative distribution of human and avian type sialic acid influenza receptors in the pig

BMC Veterinary Research, 2010
Background A major determinant of influenza infection is the presence of virus receptors on susceptible host cells to which the viral haemagglutinin is able to bind.
Perez Belinda, White Gavin A, Kuchipudi Suresh V, Nelli Rahul K, Dunham Stephen P, Chang Kin-Chow   +5 more
doaj   +1 more source

Receptors for Hepatitis C Virus

Journal of Virology, 2000
The nature of the receptors enabling hepatitis C virus (HCV) entry into cells has been the subject of debate. On one hand, ligand panning with recombinant HCV envelope protein has identified CD81, a member of the tetraspanin superfamily of proteins, as a direct ligand for the E2 glycoprotein (7) but fails to explain virus tropism.
I M, Jones, C, Chan-Fook, W R, Jiang, B E, Clarke   +3 more
openaire   +3 more sources

Impact of Mutations in the Hemagglutinin of H10N7 Viruses Isolated from Seals on Virus Replication in Avian and Human Cells

Viruses, 2018
Wild birds are the reservoir for low-pathogenic avian influenza viruses, which are frequently transmitted to domestic birds and occasionally to mammals. In 2014, an H10N7 virus caused severe mortality in harbor seals in northeastern Europe.
Anne Dittrich, David Scheibner, Ahmed H. Salaheldin, Jutta Veits, Marcel Gischke, Thomas C. Mettenleiter, Elsayed M. Abdelwhab   +6 more
doaj   +1 more source

GRP78 promotes rabies virus entry through interacting with viral receptors

Journal of Virology
The rabies virus (RABV) is known to have four potential receptors, including the nicotinic acetylcholine receptor (nAChR), neural cell adhesion molecule (NCAM), low-affinity nerve growth factor receptor (NGFR), and metabolic glutamate receptor 2 (mGluR2).
Chong Wang, Zhiyuan Wen, Chen Wang, Qilong Liu, Hailin Zhang, Lei Shuai, Xijun Wang, Jinying Ge, Jinliang Wang, Zhigao Bu   +9 more
doaj   +1 more source

TAM Receptors Are Not Required for Zika Virus Infection in Mice

Cell Reports, 2017
Summary: Tyro3, Axl, and Mertk (TAM) receptors are candidate entry receptors for infection with the Zika virus (ZIKV), an emerging flavivirus of global public health concern.
Andrew K. Hastings, Laura J. Yockey, Brett W. Jagger, Jesse Hwang, Ryuta Uraki, Hallie F. Gaitsch, Lindsay A. Parnell, Bin Cao, Indira U. Mysorekar, Carla V. Rothlin, Erol Fikrig, Michael S. Diamond, Akiko Iwasaki   +12 more
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Virus-Receptor Interactions and Receptor-Mediated Virus Entry into Host Cells [PDF]

, 2013
The virus particles described in the previous chapters of this book are vehicles that transmit the viral genome and the infection from cell to cell. To initiate the infective cycle, the viral genome must therefore translocate from the viral particle to the cell cytoplasm. Via distinct proteins or motifs in their outermost shell, the particles of animal
openaire   +3 more sources

Virus recognition of glycan receptors

Current Opinion in Virology, 2019
Attachment of viruses to cell-surface receptors is the initial step in infection. Many mammalian viruses have evolved to recognize receptors that are glycans on cell-surface glycoproteins or glycolipids. Although glycans are a ubiquitous component of mammalian cells, the types of terminal structures expressed vary among different cell-types and tissues,
Andrew J Thompson, Robert P de Vries, James C Paulson   +2 more
openaire   +3 more sources