Results 31 to 40 of about 399,510 (314)

Comparative distribution of human and avian type sialic acid influenza receptors in the pig

BMC Veterinary Research, 2010
Background A major determinant of influenza infection is the presence of virus receptors on susceptible host cells to which the viral haemagglutinin is able to bind.
Perez Belinda, White Gavin A, Kuchipudi Suresh V, Nelli Rahul K, Dunham Stephen P, Chang Kin-Chow   +5 more
doaj   +1 more source

GateView: A Multi-Omics Platform for Gene Feature Analysis of Virus Receptors within Human Normal Tissues and Tumors

Biomolecules
Viruses are obligate intracellular parasites that rely on cell surface receptor molecules to complete the first step of invading host cells. The experimental method for virus receptor screening is time-consuming, and receptor molecules have been ...
Yang Sun, Zi-Liang Huang, Wen-Xin Chen, Yi-Feng Zhang, Hao-Tian Lei, Qiao-Juan Huang, Zhao-Rong Lun, Liang-Hu Qu, Ling-Ling Zheng   +8 more
doaj   +1 more source

Impact of Mutations in the Hemagglutinin of H10N7 Viruses Isolated from Seals on Virus Replication in Avian and Human Cells

Viruses, 2018
Wild birds are the reservoir for low-pathogenic avian influenza viruses, which are frequently transmitted to domestic birds and occasionally to mammals. In 2014, an H10N7 virus caused severe mortality in harbor seals in northeastern Europe.
Anne Dittrich, David Scheibner, Ahmed H. Salaheldin, Jutta Veits, Marcel Gischke, Thomas C. Mettenleiter, Elsayed M. Abdelwhab   +6 more
doaj   +1 more source

Receptors for Hepatitis C Virus

Journal of Virology, 2000
The nature of the receptors enabling hepatitis C virus (HCV) entry into cells has been the subject of debate. On one hand, ligand panning with recombinant HCV envelope protein has identified CD81, a member of the tetraspanin superfamily of proteins, as a direct ligand for the E2 glycoprotein (7) but fails to explain virus tropism.
I M, Jones, C, Chan-Fook, W R, Jiang, B E, Clarke   +3 more
openaire   +3 more sources

Blockade of attachment and fusion receptors inhibits HIV-1 infection of human cervical tissue

, 2004
Identification of cellular factors involved in HIV-1 entry and transmission at mucosal surfaces is critical for understanding viral pathogenesis and development of effective prevention strategies. Here we describe the evaluation of HIV-1 entry inhibitors
Ines Frank, Griffin, GE, Griffin, George E., George E. Griffin, Santos, John J., John P. Moore, Robin J. Shattock, Shattock, Robin J., Watts, Patricia, John J. Santos, Patricia Watts, Santos, JJ, Shattock, RJ, Vennansha Williams, Williams, V, Moore, JP, Williams, Vennansha G., Robbiani, Melissa, Hu, Qinxue, Qinxue Hu, Pope, M, Melissa Pope, Moore, John P., Frank, Ines, Hu, Q, Frank, I, Watts, P   +26 more
core   +1 more source

HCMV spread and cell tropism are determined by distinct virus populations. [PDF]

, 2011
Human cytomegalovirus (HCMV) can infect many different cell types in vivo. Two gH/gL complexes are used for entry into cells. gH/gL/pUL(128,130,131A) shows no selectivity for its host cell, whereas formation of a gH/gL/gO complex only restricts the ...
Ulrich H Koszinowski, Koszinowski, Ulrich H., Scrivano, Laura, Adler, Barbara, Laura Scrivano, Hans Nitschko, Christian Sinzger, Barbara Adler, Sinzger, Christian, Nitschko, Hans, Ulrich H. Koszinowski   +10 more
core   +1 more source

TAM Receptors Are Not Required for Zika Virus Infection in Mice

Cell Reports, 2017
Summary: Tyro3, Axl, and Mertk (TAM) receptors are candidate entry receptors for infection with the Zika virus (ZIKV), an emerging flavivirus of global public health concern.
Andrew K. Hastings, Laura J. Yockey, Brett W. Jagger, Jesse Hwang, Ryuta Uraki, Hallie F. Gaitsch, Lindsay A. Parnell, Bin Cao, Indira U. Mysorekar, Carla V. Rothlin, Erol Fikrig, Michael S. Diamond, Akiko Iwasaki   +12 more
doaj   +1 more source

Modulation of the virus-receptor interaction by mutations in the V5 loop of feline immunodeficiency virus (FIV) following in vivo escape from neutralising antibody [PDF]

, 2010
<b>BACKGROUND:</b> In the acute phase of infection with feline immunodeficiency virus (FIV), the virus targets activated CD4+ T cells by utilising CD134 (OX40) as a primary attachment receptor and CXCR4 as a co-receptor.
Brian J Willett, Margaret J Hosie, Ayman Samman, McMonagle, Elizabeth L., Logan, Nicola, Nicola Logan, Hosie, Margaret J., Samman, Ayman, Willett, Brian J., Kraase, Martin, Martin Kraase, Elizabeth L McMonagle   +11 more
core   +1 more source

Virus-Receptor Interactions and Receptor-Mediated Virus Entry into Host Cells [PDF]

, 2013
The virus particles described in the previous chapters of this book are vehicles that transmit the viral genome and the infection from cell to cell. To initiate the infective cycle, the viral genome must therefore translocate from the viral particle to the cell cytoplasm. Via distinct proteins or motifs in their outermost shell, the particles of animal
openaire   +3 more sources

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source