Results 241 to 250 of about 5,994,707 (387)

The influence of ROS1 fusion partners and resistance mechanisms in ROS1‐TKI‐treated non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga, Christa Dijkhuizen, Patrick Korthuis, Wim Timens, Harry Groen, Jeroen Hiltermann, Anke van den Berg, Lyndsay Drayer, Anthonie van der Wekken   +8 more
wiley   +1 more source

Molecular targets of cannabinoids and their derivatives in epilepsy - a review with focus on CBD. [PDF]

Acta Biochim Pol
Marciniak S, Wasyluk W, Wojtak A.
europepmc   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

The science of minerality. [PDF]

RSC Adv
Tai HC, Kostaki E.
europepmc   +1 more source

Reflex Cardiac Acceleration by the Stimulating of the Receptor Area of the Pulmonary Veins and their Vicinity in the Left Atrium

, 1951
Masuichi Takino
openalex   +2 more sources

Approaches to quantitative analysis of information uptake and processing in biological receptors [PDF]

, 1966
E. Zerbst, Karl-Heinz Dittberner, Erich William   +2 more
openalex   +1 more source

Peroxisome proliferator-activated receptors: nuclear control of metabolism.

Endocrine reviews, 1999
B. Desvergne, W. Wahli
semanticscholar   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source

Magnesium and Zinc in Schizophrenia. [PDF]

Biomedicines
Nechifor M.
europepmc   +1 more source

Adiponectin and adiponectin receptors.

Endocrine reviews, 2005
T. Kadowaki, T. Yamauchi
semanticscholar   +1 more source