Results 21 to 30 of about 3,147,852 (168)

Toll-like receptors as adjuvant receptors

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2002
The mammalian Toll-like receptors (TLRs) are expressed on macrophages and dendritic cells, which are primarily involved in innate immunity. At present, ligands for several of the TLRs, such as TLR2, TLR3, TLR4, TLR5, TLR6, and TLR9, have been identified.
Shizuo Akira, Tsuneyasu Kaisho
openaire   +3 more sources

Peroxisome proliferator-activated receptors: nuclear control of metabolism.

open access: yesEndocrine reviews, 1999
I. Introduction II. Molecular Aspects A. PPAR isotypes: identity, genomic organization and chromosomal localization B. DNA binding properties C. PPAR ligand-binding properties D. Alternative pathways for PPAR activation E.
B. Desvergne, W. Wahli
semanticscholar   +1 more source

Adiponectin and adiponectin receptors.

open access: yesEndocrine reviews, 2005
Metabolic syndrome is thought to result from obesity and obesity-linked insulin resistance. Obesity in adulthood is characterized by adipocyte hypertrophy.
T. Kadowaki, T. Yamauchi
semanticscholar   +1 more source

Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome.

open access: yesJournal of Clinical Investigation, 2006
Adiponectin is an adipokine that is specifically and abundantly expressed in adipose tissue and directly sensitizes the body to insulin. Hypoadiponectinemia, caused by interactions of genetic factors such as SNPs in the Adiponectin gene and environmental
T. Kadowaki   +5 more
semanticscholar   +1 more source

Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression1

open access: yesJournal of Immunology, 2009
The IL-1 family cytokines are regulated on transcriptional and posttranscriptional levels. Pattern recognition and cytokine receptors control pro-IL-1β transcription whereas inflammasomes regulate the proteolytic processing of pro-IL-1β.
F. Bauernfeind   +11 more
semanticscholar   +1 more source

Pharmacology of Adenosine Receptors: The State of the Art.

open access: yesPhysiological Reviews, 2018
Adenosine is a ubiquitous endogenous autacoid whose effects are triggered through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Due to the rapid generation of adenosine from cellular metabolism, and the widespread distribution
P. Borea   +4 more
semanticscholar   +1 more source

Beyond the Receptor [PDF]

open access: yesMolecular Plant, 2008
Had this Special Issue on plant hormones been published 5 years ago, it is likely that details about biosynthetic pathways would have taken center stage. As articles in this issue show, however, the field of plant hormone research has progressed rapidly and is now moving beyond the search for receptors.
openaire   +3 more sources

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