Results 91 to 100 of about 1,341,673 (341)
A New Lower Bound for the Distinct Distance Constant
, 2015 The reciprocal sum of Zhang sequence is not equal to the Distinct Distance Constant. This note introduces a $B_2$-sequence with larger reciprocal sum, and provides a more precise estimation of the reciprocal sums of Mian-Chowla sequence and Zhang ...
Salvia, Raffaele
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo +11 more
wiley +1 more source
Selcuk Dental Journal, 2018 Amaç: Bu çalışmanın amacı resiprokal ve dönme hareketi yapan eğe sistemlerinin preparasyon sonrası dentin çatlağı oluşumuna etkilerinin kıyaslanmasıdır.
Hale Arı Aydınbelge +1 more
doaj +1 more source
Inter-organisational learning in project based organisations: Perspectives on reciprocity [PDF]
, 2013 This developmental paper discusses early research findings on the role that reciprocity plays in fostering or hindering inter-organisational learning in networks.
Abualqumboz, Moheeb, Chan, Paul
core
A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms
FEBS Open Bio, EarlyView.We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley +1 more source
Reciprocal classes of random walks on graphs
, 2016 The reciprocal class of a Markov path measure is the set of all mixtures of its bridges. We give characterizations of the reciprocal class of a continuous-time Markov random walk on a graph.
Conforti, Giovanni, Léonard, Christian
core
PERBEDAAN PENERAPAN METODE PEMBELAJARAN RECIPROCAL TEACHING DAN TUTOR SEBAYA TERHADAPMOTIVASI DAN PRESTASI BELAJAR KIMIA PESERTA DIDIK KELAS X SEMESTER 2 MADRASAH ALIYAH ALI MAKSUM YOGYAKARTA TAHUN AJARAN 2011/2012 [PDF]
, 2012 Tujuan penelitian ini adalah untuk mengetahui ada tidaknya perbedaan yang positif dan signifikan dalam motivasi dan prestasi belajar kimia peserta didik kelas X Semester 2 MA Ali Maksum Yogyakarta Tahun Ajaran 2011/2012 setelah mengikuti pembelajaran ...
IKA , RATNAWATI
core
Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, EarlyView.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source